Sponsor study identifier
interventional
16
1 country
1
Study Start
April 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
May 2008
Actual (reported)Study Completion
May 2008
Actual (reported)This study uses a computerized method of musical instrument digital interface (MIDI) quantification of performance before and after treatment with botulinum toxin type B (Myobloc ®, Solstice Neurosciences). Myobloc is a purified and diluted form of botulinum toxin used medically to relax unwanted muscle spasms and movements. The aim of the study is to determine the feasibility of quantifying change in performance following treatment.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
May 2008
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 2003
Date type not reportedThis date has not been verified as actual or estimated.
September 13, 2005
Actual (reported)September 21, 2005
Actual (reported)May 2008
Actual (reported)May 2008
Actual (reported)May 9, 2014
Actual (reported)Note Errors (Related to Errors in Duration)
Note errors (related to errors in duration in msec) were obtained as measures of difference between the affected and unaffected hands--taking the musical instrument digital interface (MIDI) note output from four musical sequences of 8 to 16 notes played. It was calculated by averaging the sequences for each hand, and deriving the square root of the mean of the square of the differences (root mean square error, in msec) in MIDI.
Baseline and 6 weeks post-injection
Note Errors (Related to Errors in Loudness)
Note errors (related to errors in loudness) were obtained as a measure of difference between the affected and unaffected hands--taking the musical instrument digital interface (MIDI) note loudness data (decibels) from four musical sequences of 8 to 16 notes. It was calculated by averaging sequences for each hand and taking the square root of the mean of the square of the differences (root mean square error, in decibels) in MIDI notes.
Baseline and 6 weeks post-injection
Subjective Assessment Ratings of Change
Baseline to 6 weeks after injection
Diluted botulinum toxin (500 Units/0.1 ml) is injected to the affected muscle(s) through a hollow core needle using electromyographic guidance. Dosage according to muscle(s) and symptom severity. Injection occurs at first visit only, after neurological evaluation.
Diluted botulinum toxin (500 Units/0.1 ml) is injected to the affected muscle(s) through a hollow core needle using electromyographic guidance. Dosage according to muscle(s) and symptom severity. Injection occurs at first visit only, after neurological evaluation.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Neurological Institute, 710 W. 168th Street, NI-1112
New York, New York, 10032, United States
Seth Pullman, MD
Columbia University Medical Center, Department of Neurology
16 participants (actual enrollment reported by the registry).
First Submitted
September 13, 2005
First Posted
September 21, 2005
Study Start
April 2003
Date type not reportedThis date has not been verified as actual or estimated.
Motor Training to Treat Hand Dystonia
Contact the study team to confirm eligibility.
Primary Completion
May 2008
Actual (reported)Study Completion
May 2008
Actual (reported)Last Updated
May 9, 2014
Results First Posted
May 9, 2014
Record last verified: 2014-04
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
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