Monitoring of Intubation and Ventilation During Resuscitation

NCT00204217 | Completed Phase 2

• 1 other identifier: 313-04124
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

Airway control and ventilation is vital during cardiopulmonary resuscitation (CPR) in cardiac arrest. Endotracheal intubation is the gold standard for airway control, but several studies have shown high rates of unrecognized placements of the tube in the esophagus instead of in the airway out-of-hospital. This is lethal. There are no failproof technique for recognising such mistakes clinically in the cardiac arrest situation. Changes on the air volume in the lungs with ventilation changes the impedance (resistance to alternating current) through the thorax. This impedance is already measured routinely by the defibrillators used during CPR. We propose that we can measure ventilation volumes and also discover failed intubations by monitoring this impedance during CPR with the possibility of giving feedback on both to the rescuers.

Conditions

Cardiac Arrest

Keywords

cardiac arrest; resuscitation; ventilation; impedance

Outcome Measures

Primary Outcomes (2)

• sensitivity/specificity for lung ventilation detection

• correlation ventilation volume - impedance change

Interventions

endotracheal intubation DEVICE

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Cardiac arrest

You may not qualify if:

• \<18 years old trauma pregnancy

Sponsors & Collaborators

• University of Oslo: lead
• Laerdal Medical: collaborator
• Ullevaal University Hospital: collaborator
• Health Region East, Norway: collaborator
• Norwegian Air Ambulance Foundation: collaborator
• University of Stavanger: collaborator

Study Sites (1)

Ulleval University Hospital

Oslo, N-0407, Norway

Location

MeSH Terms

Conditions

Heart Arrest; Respiratory Aspiration

Interventions

Intubation, Intratracheal

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases; Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Airway Management; Therapeutics; Intubation; Investigative Techniques

Study Officials

• Elizabeth Dorph

  Ulleval University Hospital, University of Oslo

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 2
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: September 12, 2005
• First Posted: September 20, 2005
• Study Start: September 1, 2004
• Study Completion: April 1, 2007
• Last Updated: August 27, 2007

Record last verified: 2007-08

Locations

NO (1)