Effect of Public Sector Antiretroviral Treatment Programme on Tuberculosis and Immunization Care
Effect of the South African Public Sector Antiretroviral Treatment Programme on the Performance of Tuberculosis and Immunization Programmes - A Cluster Controlled (Non-Randomized) Trial
1 other identifier
interventional
39
1 country
1
Brief Summary
A scale-up of public sector antiretroviral treatment (ART) programmes may divert scarce resources from other priority primary care programmes like tuberculosis and childhood immunization. The purpose of this study is to compare the performance of tuberculosis (TB) and childhood immunization programmes in primary care facilities participating in the South African national antiretroviral treatment programme with those which have yet to be included in the ART programme.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started May 2003
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2003
CompletedFirst Submitted
Initial submission to the registry
September 12, 2005
CompletedFirst Posted
Study publicly available on registry
September 20, 2005
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2006
CompletedOctober 24, 2007
March 1, 2004
September 12, 2005
October 23, 2007
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
TB case detection
TB treatment completion
Measles immunization completed by 18 months
Secondary Outcomes (5)
TB cure rate
TB mortality rate
TB treatment failure rate
TB treatment interruption rate
Proportion of TB cases that smear positive
Interventions
Eligibility Criteria
You may qualify if:
- Clinics:
- Intervention: 15 primary care clinics participating in the first phases of the national antiretroviral treatment programme
- Control: 24 primary care clinics yet to be included in the national antiretroviral treatment programme randomly selected after stratification for health district and ranking of clinic size.
- Patients:
- All patients attending tuberculosis and childhood immunization programmes at the above 39 clinics one year before and one year after antiretroviral treatment services commenced in these facilities.
You may not qualify if:
- Clinics:
- Clinics earmarked for the second year of the rollout of the antiretroviral treatment programme.
- Patients:
- None.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Cape Townlead
- Free State Department of Healthcollaborator
- Medical Research Council, South Africacollaborator
- Knowledge Translation Programme, University of Torontocollaborator
- Institute for Clinical Evaluative Sciencescollaborator
- London School of Hygiene and Tropical Medicinecollaborator
- University of the Western Capecollaborator
Study Sites (1)
University of Cape Town Lung Institute
Cape Town, Western Cape, 7937, South Africa
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
L R Fairall, MBChB
University of Cape Town Lung Institute
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
September 12, 2005
First Posted
September 20, 2005
Study Start
May 1, 2003
Study Completion
December 1, 2006
Last Updated
October 24, 2007
Record last verified: 2004-03