NCT00143767

Brief Summary

The primary purpose of this study is to investigate brain whether ADHD represents a disruption or a delay of brain development. Children and adolescents both with and without ADHD are asked to participate in several MRI sessions, two years apart. This will allow us to chart brain development over time, both in typical development and ADHD, and therefore to address whether ADHD represents a disruption or a delay of typical brain development.

Trial Health

55
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
400

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2005

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

August 31, 2005

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 2, 2005

Completed
Last Updated

March 20, 2007

Status Verified

March 1, 2007

First QC Date

August 31, 2005

Last Update Submit

March 18, 2007

Conditions

Attention Deficit Hyperactivity Disorder

Keywords

Magnetic Resonance Imaging

Eligibility Criteria

Age6 Years - 20 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Aged 6 - 18 years at initial MRI
  • DSM-IV (APA, 1994) diagnosis of ADHD, according to DISC interview
  • Scores in the clinical range on the Child Behavior Checklist (CBCL) and Teacher Rating Form(TRF)
  • No DSM-IV (APA, 1994) diagnosis, according to DISC interview
  • No scores in the clinical range on the Child Behavior Checklist (CBCL) and Teacher Rating Form (TRF)

You may not qualify if:

  • IQ \< 70
  • Major illness of the cardiovascular, the endocrine, the pulmonal or the gastrointestinal system
  • Presence of metal objects in or around the body (pacemaker, dental braces)
  • History of or present neurological disorder
  • For individuals over 12 years of age: legal incompetence, defined as the obvious inability to comprehend the information that is presented by the investigator and is outlined in the Information letter and on which the decision to participate in the study is to be based

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept. of Child and Adolescent Psychiatry, UMC Utrecht

Utrecht, Netherlands

RECRUITING

Related Links

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersMental Disorders

Study Officials

  • Sarah Durston, Ph.D.

    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht

    PRINCIPAL INVESTIGATOR

  • Herman van Engeland, M.D. Ph.D.

    Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht

    STUDY CHAIR

Central Study Contacts

Sarah Durston, Ph.D.

CONTACT

+31 30 250 8161S.Durston@umcutrecht.nl

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER

Study Record Dates

First Submitted

August 31, 2005

First Posted

September 2, 2005

Study Start

August 1, 2005

Last Updated

March 20, 2007

Record last verified: 2007-03

Locations

NL(1)