Cognitive Remediation in Supported Employment at Human Service Center (HSC)

NCT00138021 | Unknown

• 1 other identifier: 05 -132
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

This project seeks to evaluate the feasibility and effectiveness of combining cognitive remediation and Supported Employment Program (SEP) services to improve work outcomes in people with a serious mental illness who have been unable to benefit from vocational services (i.e., acquire or maintain a job). Cognitive remediation involves treating and improving cognitive impairments, such as memory (e.g., short-term and working memory), attention span, or problem solving skills. It is hypothesized that cognitive remediation will significantly improve peoples' employment outcomes in a supported employment program.

Conditions

Vocational Rehabilitation; Schizophrenia; Mental Disorders; Cognitive Symptoms

Keywords

Serious mental illness; Supported Employment; Cognitive remediation; Cognitive impairments

Outcome Measures

Primary Outcomes (3)

• competitive employment status at 12, 18, and 24 months

  12, 18, and 24 months

• number of days employed in a competitive job at 12, 18, and 24 months

  at 12, 18, and 24 months

• number of jobs acquired and lost at 12, 18, and 24 months

  at 12, 18, and 24 months

Secondary Outcomes (3)

• improvement in cognitive functioning (various measures of cognitive functioning) at 3, 12, 18, and 24 months

  3, 12, 18, and 24 months

• retention in either research condition

  3 & 12 months

• clinical status at 3, 12, 18, and 24 months

  3, 12, 18, and 24 months

Interventions

Computerized cognitive training program DEVICE

The cognitive training model used in the McGurk et al. (2005) study is referred to as the "Thinking Skills for Work" program. The program is a manualized, remediative and compensatory training intervention that is integrated with SE services. The program includes a cognitive trainer, a structured training manual (McGurk \& Mueser, unpublished training manual) and a computer-based cognitive training program (described below).

Also known as: The computerized cognitive training program using the Cogpack Software, version 7.4 (Marker Software, 2005).

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Enrolled in a Supported Employment Program
• Has acquired and lost at least one job while in the Supported Employment Program
• Presently unemployed

You may not qualify if:

• Has not acquired at least one job while in the Supported Employment Program
• Presently employed

Sponsors & Collaborators

• Human Service Center, Illinois: lead

Study Sites (1)

Human Service Center (HSC)

Peoria, Illinois, 61654-1346, United States

Location

Related Publications (1)

• McGurk SR, Mueser KT, Pascaris A. Cognitive training and supported employment for persons with severe mental illness: one-year results from a randomized controlled trial. Schizophr Bull. 2005 Oct;31(4):898-909. doi: 10.1093/schbul/sbi037. Epub 2005 Aug 3.

  PMID: 16079391 BACKGROUND

MeSH Terms

Conditions

Schizophrenia; Mental Disorders; Neurobehavioral Manifestations; Cognitive Dysfunction

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Cognition Disorders; Neurocognitive Disorders

Study Officials

• David Loveland, Ph.D.

  Fayette Companies

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: August 29, 2005
• First Posted: August 30, 2005
• Study Start: July 1, 2005
• Study Completion: May 1, 2008
• Last Updated: November 2, 2007

Record last verified: 2007-10

Locations

US (1)