Cognitive Remediation for Schizophrenia
1 other identifier
interventional
50
1 country
3
Brief Summary
The purpose of this study is to evaluate the efficacy of an innovative, computer driven cognitive rehabilitation program for individuals with schizophrenia and related disorders.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable schizophrenia
Started Nov 2004
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2004
CompletedFirst Submitted
Initial submission to the registry
February 19, 2006
CompletedFirst Posted
Study publicly available on registry
February 22, 2006
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
May 1, 2007
CompletedJuly 21, 2021
July 1, 2021
2.5 years
February 19, 2006
July 14, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
broad cognitive performance (as indexed by a composite of the neuropsychological measures) and on a composite of everyday problem solving
Secondary Outcomes (1)
individual cognitive domains and individual everyday problem solving domains, the interaction of treatment with various other variables
Interventions
Eligibility Criteria
You may qualify if:
- Diagnosis of either schizophrenia or schizoaffective disorder according to DSM-IV criteria
- Age 18 through 50
- Subjects will be clinically stable as judged by current outpatient or inpatient treatment staff
- Primary psychiatric medication is a new generation antipsychotic other than Clozapine and/or a dose of first generation antipsychotic equivalent to 10 mg. of less of haloperidol for one month prior to enrollment.
You may not qualify if:
- Documented history of organic brain disease
- Documented history of mental retardation
- Physical limitations (e.g., with hearing or vision) that would interfere substantially with use of computer-based exercises
- Diagnosis of current Substance Dependence according to DSM-IV criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (3)
University of Maryland - Walter P. Carter Center
Baltimore, Maryland, 21201, United States
VA Maryland Health Care Systen
Baltimore, Maryland, 21201, United States
MOSAIC Community Services
Catonsville, Maryland, 21228, United States
Related Publications (1)
Dickinson D, Tenhula W, Morris S, Brown C, Peer J, Spencer K, Li L, Gold JM, Bellack AS. A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia. Am J Psychiatry. 2010 Feb;167(2):170-80. doi: 10.1176/appi.ajp.2009.09020264. Epub 2009 Dec 15.
PMID: 20008941DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Dwight Dickinson, PhD
University of Maryland, College Park
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 19, 2006
First Posted
February 22, 2006
Study Start
November 1, 2004
Primary Completion
May 1, 2007
Study Completion
May 1, 2007
Last Updated
July 21, 2021
Record last verified: 2021-07