NCT00121004

Brief Summary

In this study, hospitalized patients will first be surveyed regarding their interest in a traditional advanced directive (AD) and then in a modified AD.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jul 2005

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2005

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

July 11, 2005

Completed
8 days until next milestone

First Posted

Study publicly available on registry

July 19, 2005

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2005

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2005

Completed
Last Updated

September 5, 2013

Status Verified

September 1, 2013

Enrollment Period

2 months

First QC Date

July 11, 2005

Last Update Submit

September 4, 2013

Conditions

DementiaPersistent Vegetative StateTerminally Ill

Keywords

Advance DirectiveLiving WillTerminal Illness

Interventions

Advance Directive SelectionBEHAVIORAL

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Hospitalized patients admitted to the general medical service at the University of Chicago

You may qualify if:

  • Hospitalized patients admitted to the general medical service at the University of Chicago
  • Previously enrolled in a study of hospitalized general medicine patients at the University of Chicago

You may not qualify if:

  • Patients who score less than 17 out of 30 on the Folstein Mini-Mental Status Examination or who have a proxy decision-maker
  • Patients who are medically unstable based on two or more abnormal vital signs
  • Patients who face a possible new diagnosis of cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The University of Chicago

Chicago, Illinois, 60637, United States

Location

Related Publications (25)

  • A controlled trial to improve care for seriously ill hospitalized patients. The study to understand prognoses and preferences for outcomes and risks of treatments (SUPPORT). The SUPPORT Principal Investigators. JAMA. 1995 Nov 22-29;274(20):1591-8.

    PMID: 7474243BACKGROUND

  • Teno JM, Licks S, Lynn J, Wenger N, Connors AF Jr, Phillips RS, O'Connor MA, Murphy DP, Fulkerson WJ, Desbiens N, Knaus WA. Do advance directives provide instructions that direct care? SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment. J Am Geriatr Soc. 1997 Apr;45(4):508-12. doi: 10.1111/j.1532-5415.1997.tb05179.x.

    PMID: 9100722BACKGROUND

  • Teno JM, Lynn J, Phillips RS, Murphy D, Youngner SJ, Bellamy P, Connors AF Jr, Desbiens NA, Fulkerson W, Knaus WA. Do formal advance directives affect resuscitation decisions and the use of resources for seriously ill patients? SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. J Clin Ethics. 1994 Spring;5(1):23-30. No abstract available.

    PMID: 8003719BACKGROUND

  • Danis M, Southerland LI, Garrett JM, Smith JL, Hielema F, Pickard CG, Egner DM, Patrick DL. A prospective study of advance directives for life-sustaining care. N Engl J Med. 1991 Mar 28;324(13):882-8. doi: 10.1056/NEJM199103283241304.

    PMID: 2000110BACKGROUND

  • Schneiderman LJ, Kronick R, Kaplan RM, Anderson JP, Langer RD. Effects of offering advance directives on medical treatments and costs. Ann Intern Med. 1992 Oct 1;117(7):599-606. doi: 10.7326/0003-4819-117-7-599.

    PMID: 1524334BACKGROUND

  • Ditto PH, Danks JH, Smucker WD, Bookwala J, Coppola KM, Dresser R, Fagerlin A, Gready RM, Houts RM, Lockhart LK, Zyzanski S. Advance directives as acts of communication: a randomized controlled trial. Arch Intern Med. 2001 Feb 12;161(3):421-30. doi: 10.1001/archinte.161.3.421.

    PMID: 11176768BACKGROUND

  • Fagerlin A, Schneider CE. Enough. The failure of the living will. Hastings Cent Rep. 2004 Mar-Apr;34(2):30-42.

    PMID: 15156835BACKGROUND

  • Miles SH, Koepp R, Weber EP. Advance end-of-life treatment planning. A research review. Arch Intern Med. 1996 May 27;156(10):1062-8.

    PMID: 8638992BACKGROUND

  • Teno JM. Advance directives: time to move on. Ann Intern Med. 2004 Jul 20;141(2):159-60. doi: 10.7326/0003-4819-141-2-200407200-00017. No abstract available.

    PMID: 15262674BACKGROUND

  • Lunney JR, Lynn J, Hogan C. Profiles of older medicare decedents. J Am Geriatr Soc. 2002 Jun;50(6):1108-12. doi: 10.1046/j.1532-5415.2002.50268.x.

    PMID: 12110073BACKGROUND

  • Fried TR, Bradley EH, Towle VR, Allore H. Understanding the treatment preferences of seriously ill patients. N Engl J Med. 2002 Apr 4;346(14):1061-6. doi: 10.1056/NEJMsa012528.

    PMID: 11932474BACKGROUND

  • Danis M, Patrick DL, Southerland LI, Green ML. Patients' and families' preferences for medical intensive care. JAMA. 1988 Aug 12;260(6):797-802.

    PMID: 3392810BACKGROUND

  • Starr TJ, Pearlman RA, Uhlmann RF. Quality of life and resuscitation decisions in elderly patients. J Gen Intern Med. 1986 Nov-Dec;1(6):373-9. doi: 10.1007/BF02596420.

    PMID: 3794836BACKGROUND

  • Silverstein MD, Stocking CB, Antel JP, Beckwith J, Roos RP, Siegler M. Amyotrophic lateral sclerosis and life-sustaining therapy: patients' desires for information, participation in decision making, and life-sustaining therapy. Mayo Clin Proc. 1991 Sep;66(9):906-13. doi: 10.1016/s0025-6196(12)61577-8.

    PMID: 1921500BACKGROUND

  • Murphy DJ, Santilli S. Elderly patients' preferences for long-term life support. Arch Fam Med. 1998 Sep-Oct;7(5):484-8. doi: 10.1001/archfami.7.5.484.

    PMID: 9755744BACKGROUND

  • Blackhall LJ, Frank G, Murphy ST, Michel V, Palmer JM, Azen SP. Ethnicity and attitudes towards life sustaining technology. Soc Sci Med. 1999 Jun;48(12):1779-89. doi: 10.1016/s0277-9536(99)00077-5.

    PMID: 10405016BACKGROUND

  • Gjerdingen DK, Neff JA, Wang M, Chaloner K. Older persons' opinions about life-sustaining procedures in the face of dementia. Arch Fam Med. 1999 Sep-Oct;8(5):421-5. doi: 10.1001/archfami.8.5.421.

    PMID: 10500515BACKGROUND

  • Robertson GS. Resuscitation and senility: a study of patients' opinions. J Med Ethics. 1993 Jun;19(2):104-7. doi: 10.1136/jme.19.2.104.

    PMID: 8080470BACKGROUND

  • Emanuel LL, Barry MJ, Stoeckle JD, Ettelson LM, Emanuel EJ. Advance directives for medical care--a case for greater use. N Engl J Med. 1991 Mar 28;324(13):889-95. doi: 10.1056/NEJM199103283241305.

    PMID: 2000111BACKGROUND

  • Lo B, McLeod GA, Saika G. Patient attitudes to discussing life-sustaining treatment. Arch Intern Med. 1986 Aug;146(8):1613-5. No abstract available.

    PMID: 3729645BACKGROUND

  • Singer PA, Thiel EC, Salit I, Flanagan W, Naylor CD. The HIV-specific advance directive. J Gen Intern Med. 1997 Dec;12(12):729-35. doi: 10.1046/j.1525-1497.1997.07157.x.

    PMID: 9436891BACKGROUND

  • Griffith CH 3rd, Wilson JF, Emmett KR, Ramsbottom-Lucier M, Rich EC. Knowledge and experience with Alzheimer's disease. Relationship to resuscitation preference. Arch Fam Med. 1995 Sep;4(9):780-4. doi: 10.1001/archfami.4.9.780.

    PMID: 7647944BACKGROUND

  • Everhart MA, Pearlman RA. Stability of patient preferences regarding life-sustaining treatments. Chest. 1990 Jan;97(1):159-64. doi: 10.1378/chest.97.1.159.

    PMID: 2104791BACKGROUND

  • Berger JT, Majerovitz D. Stability of preferences for treatment among nursing home residents. Gerontologist. 1998 Apr;38(2):217-23. doi: 10.1093/geront/38.2.217.

    PMID: 9573666BACKGROUND

  • Mitchell SL, Kiely DK, Hamel MB. Dying with advanced dementia in the nursing home. Arch Intern Med. 2004 Feb 9;164(3):321-6. doi: 10.1001/archinte.164.3.321.

    PMID: 14769629BACKGROUND

MeSH Terms

Conditions

DementiaPersistent Vegetative State

Condition Hierarchy (Ancestors)

Brain DiseasesCentral Nervous System DiseasesNervous System DiseasesNeurocognitive DisordersMental DisordersBrain Damage, ChronicUnconsciousnessConsciousness DisordersNeurobehavioral ManifestationsNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Elmer Abbo, M.D., Ph.D.

    University of Chicago

    PRINCIPAL INVESTIGATOR

  • David Meltzer, M.D., Ph.D.

    University of Chicago

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 11, 2005

First Posted

July 19, 2005

Study Start

July 1, 2005

Primary Completion

September 1, 2005

Study Completion

September 1, 2005

Last Updated

September 5, 2013

Record last verified: 2013-09

Locations

US(1)