NCT00083863

Brief Summary

To investigate the contribution of genetic and environmental factors to vascular inflammation, and to define the extent to which inflammatory phenotypes and genotypes predict subclinical and clinical cardiovascular disease (CVD).

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
7,374

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2004

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2004

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

June 2, 2004

Completed
2 days until next milestone

First Posted

Study publicly available on registry

June 4, 2004

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2009

Completed
Last Updated

August 12, 2013

Status Verified

August 1, 2013

Enrollment Period

4.9 years

First QC Date

June 2, 2004

Last Update Submit

August 8, 2013

Conditions

AtherosclerosisCardiovascular DiseasesHeart DiseasesInflammation

Outcome Measures

Primary Outcomes (1)

  • Cardiovascular diseases

    The FHS study is longitudinal so events will accrue over decades of follow up.

Study Arms (2)

Framingham Heart Study Offspring

FHS Gen 3

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Observational Cohort Study

Offspring \& Generation 3

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

MeSH Terms

Conditions

AtherosclerosisCardiovascular DiseasesHeart DiseasesInflammation

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Emelia Benjamin

    Boston University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principle Investigator

Study Record Dates

First Submitted

June 2, 2004

First Posted

June 4, 2004

Study Start

June 1, 2004

Primary Completion

May 1, 2009

Study Completion

May 1, 2009

Last Updated

August 12, 2013

Record last verified: 2013-08