NCT00046605

Brief Summary

To examine the associations of common variation in inflammation/thrombosis genes with intermediate quantitative phenotypes and subclinical coronary atherosclerosis in the Coronary Artery Risk Factor Development in Young Adults (CARDIA) Study, a large, bi-racial cohort study.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,600

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2002

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2002

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

September 30, 2002

Completed
1 day until next milestone

First Posted

Study publicly available on registry

October 1, 2002

Completed
5.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2008

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2008

Completed
Last Updated

November 7, 2017

Status Verified

November 1, 2017

Enrollment Period

5.9 years

First QC Date

September 30, 2002

Last Update Submit

November 3, 2017

Conditions

Cardiovascular DiseasesAtherosclerosisCoronary ArteriosclerosisInflammationHeart DiseasesThrombosis

Eligibility Criteria

Age18 Years - 55 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Same as eligibility criteria

Cardiac cohort participants with DNA

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (1)

  • Carlson CS, Aldred SF, Lee PK, Tracy RP, Schwartz SM, Rieder M, Liu K, Williams OD, Iribarren C, Lewis EC, Fornage M, Boerwinkle E, Gross M, Jaquish C, Nickerson DA, Myers RM, Siscovick DS, Reiner AP. Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels. Am J Hum Genet. 2005 Jul;77(1):64-77. doi: 10.1086/431366. Epub 2005 May 16.

    PMID: 15897982BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesAtherosclerosisCoronary Artery DiseaseInflammationHeart DiseasesThrombosis

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCoronary DiseaseMyocardial IschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsEmbolism and Thrombosis

Study Officials

  • David Siscovick

    University of Washington

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, Medicine

Study Record Dates

First Submitted

September 30, 2002

First Posted

October 1, 2002

Study Start

August 1, 2002

Primary Completion

July 1, 2008

Study Completion

July 1, 2008

Last Updated

November 7, 2017

Record last verified: 2017-11