Comparison of Combination Chemotherapy Regimens With or Without Cetuximab in Treating Patients Who Have Undergone Surgery For Stage III Colon Cancer
A Randomized Phase III Trial of Oxaliplatin (OXAL) Plus 5-Fluorouracil (5-FU)/Leucovorin (CF) With or Without Cetuximab (C225) After Curative Resection for Patients With Stage III Colon Cancer
4 other identifiers
interventional
3,397
3 countries
894
Brief Summary
This randomized phase III trial was originally designed to compare three different combination chemotherapy regimens to see how well they work. As of September 1, 2004, the study was expanded to a total of 6 arms (the original 3 arms (A, B, C) and 3 additional arms which were the same as the first 3 but with cetuximab) in treating patients who have undergone surgery for stage III colon cancer. Drugs used in chemotherapy, such as irinotecan hydrochloride, fluorouracil, leucovorin calcium, and oxaliplatin, work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as cetuximab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Combining more than one chemotherapy drug with monoclonal antibody therapy and giving them after surgery may kill any remaining tumor cells. It was not known at the time this study was developed which combination chemotherapy regimen is more effective after surgery in treating colon cancer. This study had several key changes, based on the results of other phase III trials. As of 6/1/2005, patients no longer received irinotecan on this study and treatment arms B, C, E, and F were discontinued. Patients on arms B and C crossed to arm A. Patients on arms E and F crossed to arm D. Patients on arms C and F who had not gotten to irinotecan continued on arms A and D, respectively. As of 8/18/2008, pre-screening for Kirsten rat sarcoma (KRAS) status was added with mutant KRAS (or KRAS not evaluable) patients put on arm G and wild-type KRAS patients randomized between arm A and arm D. Patients on arm G were treated per physician discretion and followed for disease and survival status. KRAS was determined in a central laboratory and was process for all patients on this study. The primary endpoint of this study was modified on 8/18/2008 to focus on patients having wild-type KRAS tumors. All modifications were approved by the Central Institution Review Board, local Institutional Review Boards, NCI, and the NCCTG Data Safety Monitoring Board.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for phase_3
Started Feb 2004
Longer than P75 for phase_3
894 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2004
CompletedFirst Submitted
Initial submission to the registry
March 8, 2004
CompletedFirst Posted
Study publicly available on registry
March 10, 2004
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2012
CompletedResults Posted
Study results publicly available
February 9, 2015
CompletedMay 13, 2020
April 1, 2020
8.8 years
March 8, 2004
December 5, 2013
April 28, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
Disease-free Survival (Arms A and D: Wild-type KRAS Patients)
The primary endpoint for this study was to compare the disease-free survival (DFS) in patients with stage III colon cancer who are KRAS wild-type randomized to one of two treatment regimens: 1) oxaliplatin, leucovorin calcium, and fluorouracil (Arm A) or 2) oxaliplatin, leucovorin calcium, fluorouracil and cetuximab (Arm D). Participants treated according to Arms B, C, E, and F treatment schedules received treatment which included irinotecan hydrochloride and therefore were not analyzed for this endpoint. Disease-free survival is defined as the time from randomization until tumor recurrence or death, whichever is first. Estimated by the method of Kaplan and Meier.
At 3 years
Secondary Outcomes (5)
Disease-free Survival (Arms A and D: Mutant KRAS Patients)
At 3 years
Overall Survival as Measured by the 3-year Event-free Rate (Arms A and D: Wild-type KRAS Patients)
Up to 3 years
Overall Survival as Measured by the 3-year Event-free Rate (Arms A and D: Mutant KRAS Patients)
Up to 3 years
Toxicity, Assessed Using National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) Version 3.0 (v3) (Arms A and D: Wild-type KRAS Patients)
Assessed up to 8 years
Toxicity, Assessed Using National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) Version 3.0 (v3) (Arms A and D: Mutant KRAS Patients)
Assessed up to 8 years
Study Arms (7)
Arm A (combination chemotherapy)
EXPERIMENTALPatients received oxaliplatin IV over 2 hours, leucovorin calcium IV over 2 hours, and fluorouracil IV continuously over 46-48 hours on days 1. Treatment repeated every 14 days for up to 12 courses in the absence of unacceptable toxicity or recurrent disease.
Arm B (combination chemotherapy)
EXPERIMENTALPatients received irinotecan IV over 2 hours on day 1 and leucovorin calcium and fluorouracil as in arm A. Treatment repeated every 14 days for up to 12 courses in the absence of unacceptable toxicity or recurrent disease.
Arm C (combination chemotherapy)
EXPERIMENTALPatients received the same treatment as in arm A for 6 courses followed by the same treatment as in arm B for 6 courses (total of 12 courses). Treatment continues in the absence of unacceptable toxicity or recurrent disease.
Arm D (combination chemotherapy, monoclonal antibody)
EXPERIMENTALPatients received cetuximab IV over 1 hour on days 1 and 8 and oxaliplatin, leucovorin calcium, and fluorouracil as in arm A. Treatment repeated every 14 days for up to 12 courses in the absence of unacceptable toxicity or recurrent disease.
Arm E (combination chemotherapy, monoclonal antibody)
EXPERIMENTALPatients received cetuximab as in arm D and irinotecan, leucovorin calcium, and fluorouracil as in arm B. Treatment repeated every 14 days for up to 12 courses in the absence of unacceptable toxicity or recurrent disease.
Arm F (combination chemotherapy, monoclonal antibody)
EXPERIMENTALPatients received cetuximab as in arm D and chemotherapy as in arm C.
Arm G (Locally directed therapy)
OTHERPatients determined to have mutated KRAS (or KRAS not evaluable) were assigned to an event monitoring arm in which adjuvant therapy was determined and assigned by the treating oncologist. The determination of the type of therapy, duration of treatment, and dose modification was the responsibility of the treating oncologists.
Interventions
Given IV
Given IV
Given IV
Given IV
Given IV
Patients determined to have mutated KRAS (or KRAS not evaluable) will be assigned to an event monitoring arm in which adjuvant therapy will be determined and assigned by the treating oncologist. The determination of the type of therapy, duration of treatment, and dose modification will be the responsibility of the treating oncologists.
Eligibility Criteria
You may qualify if:
- Histologically confirmed adenocarcinoma of the colon
- Stage III disease
- No resected stage IV disease
- No rectal cancer
- Gross inferior (caudad) margin of the primary tumor must be ≥ 12 cm from the anal verge by rigid proctoscopy
- Stage III tumor must have been completely resected within the past 56 days
- Must have documented en bloc resection in patients with tumor adherence to adjacent structures
- Tumor-related obstructions and colonic perforation are allowed
- Tumor samples must be available
- At least 1 pathologically confirmed positive lymph node
- No evidence of residual involved lymph node disease
- Synchronous primary colon cancer allowed
- No distant metastatic disease
- Performance status - Eastern Cooperative Oncology Group (ECOG) 0-2
- Absolute neutrophil count ≥ 1,500/mm\^3
- +31 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (894)
Northeast Alabama Regional Medical Center
Anniston, Alabama, 36202, United States
Clearview Cancer Institute
Huntsville, Alabama, 35805, United States
Mobile Infirmary Medical Center
Mobile, Alabama, 36607, United States
Providence Hospital
Mobile, Alabama, 36608, United States
Providence Alaska Medical Center
Anchorage, Alaska, 99508, United States
Banner Thunderbird Medical Center
Glendale, Arizona, 85306, United States
Banner Desert Medical Center
Mesa, Arizona, 85202, United States
Banner Baywood Medical Center
Mesa, Arizona, 85206, United States
Banner Good Samaritan Medical Center
Phoenix, Arizona, 85006, United States
Western Regional CCOP
Phoenix, Arizona, 85006, United States
Phoenix Indian Medical Center
Phoenix, Arizona, 85016, United States
Scottsdale Healthcare
Scottsdale, Arizona, 85251, United States
Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
Highlands Oncology Group-Bentonville
Bentonville, Arkansas, 72712, United States
Saint Edward Mercy Medical Center
Fort Smith, Arkansas, 72903, United States
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205, United States
Veteran's Administration Medical Center
Little Rock, Arkansas, 72205, United States
Alta Bates Medical Center-Herrick Campus
Berkeley, California, 94704, United States
Providence Saint Joseph Medical Center
Burbank, California, 91505, United States
Mills - Peninsula Hospitals
Burlingame, California, 94010, United States
East Bay Radiation Oncology Center
Castro Valley, California, 94546, United States
Eden Hospital Medical Center
Castro Valley, California, 94546, United States
Valley Medical Oncology Consultants-Castro Valley
Castro Valley, California, 94546, United States
City of Hope
Duarte, California, 91010, United States
Northbay Cancer Center
Fairfield, California, 94533, United States
Kaiser Permanente, Fremont
Fremont, California, 94538, United States
Valley Medical Oncology Consultants-Fremont
Fremont, California, 94538, United States
California Cancer Center - North Fresno
Fresno, California, 93720, United States
Cancer Care Associates
Fresno, California, 93720, United States
California Cancer Care - Greenbrae
Greenbrae, California, 94904, United States
Sutter Health Western Division Cancer Research Group
Greenbrae, California, 94904, United States
Kaiser Permanente, Hayward
Hayward, California, 94545, United States
Saint Rose Hospital
Hayward, California, 94545, United States
Loma Linda University Medical Center
Loma Linda, California, 92354, United States
University of Southern California
Los Angeles, California, 90033-0804, United States
Contra Costa Regional Medical Center
Martinez, California, 94553-3156, United States
Fremont - Rideout Cancer Center
Marysville, California, 95901, United States
Memorial Medical Center
Modesto, California, 95355, United States
Community Hospital of Monterey Peninsula
Monterey, California, 93940, United States
El Camino Hospital
Mountain View, California, 94040, United States
Palo Alto Medical Foundation-Camino Division
Mountain View, California, 94040, United States
Highland General Hospital
Oakland, California, 94602, United States
Alta Bates Summit Medical Center - Summit Campus
Oakland, California, 94609, United States
Bay Area Breast Surgeons Inc
Oakland, California, 94609, United States
Bay Area Tumor Institution CCOP
Oakland, California, 94609, United States
Larry G Strieff MD Medical Corporation
Oakland, California, 94609, United States
Tom K Lee Inc
Oakland, California, 94609, United States
Kaiser Permanente-Oakland
Oakland, California, 94611, United States
Saint Joseph Hospital
Orange, California, 92868, United States
Desert Regional Medical Center
Palm Springs, California, 92262, United States
Palo Alto Medical Foundation Heath Care
Palo Alto, California, 94301, United States
Valley Care Health System - Pleasanton
Pleasanton, California, 94588, United States
Valley Medical Oncology Consultants
Pleasanton, California, 94588, United States
Shasta Regional Medical Center
Redding, California, 96001, United States
Kaiser Permanente-Redwood City
Redwood City, California, 94063, United States
Kaiser Permanente-Richmond
Richmond, California, 94801, United States
Kaiser Permanente-Roseville
Roseville, California, 95661, United States
Sutter Roseville Medical Center
Roseville, California, 95661, United States
Sutter General Hospital
Sacramento, California, 95816, United States
UC Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
Kaiser Permanente-South Sacramento
Sacramento, California, 95823, United States
Kaiser Permanente - Sacramento
Sacramento, California, 95825, United States
Kaiser Permanente
San Diego, California, 92120, United States
Naval Medical Center -San Diego
San Diego, California, 92134, United States
University of California San Diego - Veterans Administration
San Diego, California, 92161, United States
Kaiser Permanente-San Francisco
San Francisco, California, 94115, United States
University of California San Francisco Medical Center-Mount Zion
San Francisco, California, 94115, United States
California Pacific Medical Center
San Francisco, California, 94118, United States
Kaiser Permanente-Santa Teresa-San Jose
San Jose, California, 95119, United States
Doctors Medical Center- JC Robinson Regional Cancer Center
San Pablo, California, 94806, United States
Kaiser Permanente-San Rafael
San Rafael, California, 94903, United States
Kaiser Permanente Medical Center - Santa Clara
Santa Clara, California, 95051, United States
Kaiser Permanente-Santa Rosa
Santa Rosa, California, 95403, United States
Santa Rosa Memorial Hospital
Santa Rosa, California, 95405, United States
Kaiser Permanente-South San Francisco
South San Francisco, California, 94080, United States
Kaiser Permanente-Stockton
Stockton, California, 95210, United States
Tahoe Forest Cancer Center
Truckee, California, 96161, United States
Kaiser Permanente-Vallejo
Vallejo, California, 94589, United States
Sutter Solano Medical Center
Vallejo, California, 94589, United States
Kaiser Permanente-Walnut Creek
Walnut Creek, California, 94596, United States
The Medical Center of Aurora
Aurora, Colorado, 80012, United States
Boulder Community Hospital
Boulder, Colorado, 80301, United States
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, 80907, United States
Memorial Hospital Colorado Springs
Colorado Springs, Colorado, 80909, United States
Saint Anthony Central Hospital
Denver, Colorado, 80204, United States
Porter Adventist Hospital
Denver, Colorado, 80210, United States
Exempla Saint Joseph Hospital
Denver, Colorado, 80218, United States
Presbyterian - Saint Lukes Medical Center - Health One
Denver, Colorado, 80218, United States
Rose Medical Center
Denver, Colorado, 80220, United States
Colorado Cancer Research Program CCOP
Denver, Colorado, 80224-2522, United States
Swedish Medical Center
Englewood, Colorado, 80110, United States
Poudre Valley Hospital
Fort Collins, Colorado, 80524, United States
Front Range Cancer Specialists
Fort Collins, Colorado, 80528, United States
Saint Mary's Hospital and Regional Medical Center
Grand Junction, Colorado, 81502, United States
North Colorado Medical Center
Greeley, Colorado, 80631, United States
Sky Ridge Medical Center
Lone Tree, Colorado, 80124, United States
Longmont United Hospital
Longmont, Colorado, 80501, United States
McKee Medical Center
Loveland, Colorado, 80539, United States
Saint Mary Corwin Medical Center
Pueblo, Colorado, 81004, United States
North Suburban Medical Center
Thornton, Colorado, 80229, United States
Exempla Lutheran Medical Center
Wheat Ridge, Colorado, 80033, United States
Bridgeport Hospital
Bridgeport, Connecticut, 06610, United States
Danbury Hospital
Danbury, Connecticut, 06810, United States
Hartford Hospital
Hartford, Connecticut, 06102, United States
Saint Francis Hospital and Medical Center
Hartford, Connecticut, 06105, United States
Manchester Memorial Hospital
Manchester, Connecticut, 06040, United States
Middlesex Hospital
Middletown, Connecticut, 06457, United States
The Hospital of Central Connecticut
New Britain, Connecticut, 06050, United States
Eastern Connecticut Hematology and Oncology Associates
Norwich, Connecticut, 06360, United States
Stamford Hospital
Stamford, Connecticut, 06904, United States
Bayhealth Medical Center at Kent General
Dover, Delaware, 19901, United States
Beebe Medical Center
Lewes, Delaware, 19958, United States
Washington Hospital Center
Washington D.C., District of Columbia, 20010, United States
Lombardi Comprehensive Cancer Center at Georgetown University
Washington D.C., District of Columbia, 20057, United States
Howard University Hospital
Washington D.C., District of Columbia, 20060, United States
Halifax Medical Center-Centers for Oncology
Daytona Beach, Florida, 32114, United States
North Broward Medical Center
Deerfield Beach, Florida, 33064, United States
Broward General Medical Center
Fort Lauderdale, Florida, 33316, United States
University of Florida
Gainesville, Florida, 32610, United States
Edna Williams Cancer Center at the Baptist Cancer Institute
Jacksonville, Florida, 32207, United States
Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
The Watson Clinic
Lakeland, Florida, 33805, United States
Cancer Centers of Central Florida PA
Leesburg, Florida, 34788, United States
Baptist Hospital of Miami
Miami, Florida, 33176, United States
Integrated Community Oncology Network - Orange Park Cancer Center
Orange Park, Florida, 32073, United States
Florida Hospital
Orlando, Florida, 32803, United States
M D Anderson Cancer Center- Orlando
Orlando, Florida, 32806, United States
Sacred Heart Hospital
Pensacola, Florida, 32504, United States
Sacred Heart Medical Oncology Group - Davis Highway
Pensacola, Florida, 32514, United States
Montgomery and Associates MD PA
Saint Augustine, Florida, 32086, United States
Florida Cancer Specialists - Sarasota Downtown
Sarasota, Florida, 34236, United States
Martin Memorial Cancer Center
Stuart, Florida, 34994, United States
Martin Memorial Medical Center - North
Stuart, Florida, 34994, United States
Martin Memorial Hospital - South
Stuart, Florida, 34997, United States
Palm Beach Cancer Institute-Main Office
West Palm Beach, Florida, 33401, United States
Phoebe Putney Memorial Hospital
Albany, Georgia, 31703, United States
Piedmont Hospital
Atlanta, Georgia, 30309, United States
Atlanta Regional CCOP
Atlanta, Georgia, 30342, United States
Northside Hospital
Atlanta, Georgia, 30342, United States
Saint Joseph's Hospital of Atlanta
Atlanta, Georgia, 30342, United States
Augusta Oncology Associates PC
Augusta, Georgia, 30901, United States
Well Star Cobb Hospital
Austell, Georgia, 30106, United States
John B Amos Cancer Center
Columbus, Georgia, 31904, United States
Dekalb Medical Center
Decatur, Georgia, 30033, United States
Veterans Administration Medical Center
Decatur, Georgia, 30033, United States
Northeast Georgia Medical Center
Gainesville, Georgia, 30501, United States
Gwinnett Medical Center
Lawrenceville, Georgia, 30045, United States
Wellstar Kennestone Hospital
Marietta, Georgia, 30060, United States
Southern Regional Medical Center
Riverdale, Georgia, 30274, United States
Memorial Health University Medical Center
Savannah, Georgia, 31403, United States
Saint Joseph's-Candler Health System
Savannah, Georgia, 31405, United States
South Georgia Medical Center
Valdosta, Georgia, 31603, United States
Oncare Hawaii Inc-POB II
Honolulu, Hawaii, 96813, United States
Queen's Medical Center
Honolulu, Hawaii, 96813, United States
Straub Clinic and Hospital
Honolulu, Hawaii, 96813, United States
University of Hawaii
Honolulu, Hawaii, 96813, United States
Hawaii Medical Center East
Honolulu, Hawaii, 96817, United States
Oncare Hawaii Inc-Kuakini
Honolulu, Hawaii, 96817, United States
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96826, United States
Tripler Army Medical Center
Honolulu, Hawaii, 96859, United States
Maui Memorial Medical Center
Wailuku, Hawaii, 96793, United States
Pacific Cancer Institute of Maui
Wailuku, Hawaii, 96793, United States
Kapiolani Medical Center at Pali Momi
‘Aiea, Hawaii, 96701, United States
Saint Alphonsus Regional Medical Center
Boise, Idaho, 83706, United States
Saint Luke's Mountain States Tumor Institute
Boise, Idaho, 83712, United States
Saint Anthony's Health
Alton, Illinois, 62002, United States
Rush - Copley Medical Center
Aurora, Illinois, 60504, United States
Saint Joseph Medical Center
Bloomington, Illinois, 61701, United States
Graham Hospital Association
Canton, Illinois, 61520, United States
Memorial Hospital
Carthage, Illinois, 62321, United States
Mount Sinai Hospital Medical Center
Chicago, Illinois, 60608, United States
Hematology and Oncology Associates
Chicago, Illinois, 60611, United States
Northwestern University
Chicago, Illinois, 60611, United States
John H Stroger Jr Hospital of Cook County
Chicago, Illinois, 60612-3785, United States
Mercy Hospital and Medical Center
Chicago, Illinois, 60616, United States
Swedish Covenant Hospital
Chicago, Illinois, 60625, United States
Resurrection Healthcare
Chicago, Illinois, 60631, United States
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637-1470, United States
Weiss Memorial Hospital
Chicago, Illinois, 60640, United States
Illinois Masonic Medical Center
Chicago, Illinois, 60657, United States
Decatur Memorial Hospital
Decatur, Illinois, 62526, United States
Saint Anthony Memorial Hospital
Effingham, Illinois, 62401, United States
Sherman Hospital
Elgin, Illinois, 60123, United States
Cancer Institute at Alexian Brothers
Elk Grove Village, Illinois, 60007, United States
Eureka Hospital
Eureka, Illinois, 61530, United States
Evanston CCOP-NorthShore University HealthSystem
Evanston, Illinois, 60201, United States
Saint Francis Hospital
Evanston, Illinois, 60202, United States
Galesburg Clinic
Galesburg, Illinois, 61401, United States
Galesburg Cottage Hospital
Galesburg, Illinois, 61401, United States
Intercommunity Cancer Center
Galesburg, Illinois, 61401, United States
Ingalls Memorial Hospital
Harvey, Illinois, 60426, United States
Mason District Hospital
Havana, Illinois, 62644, United States
Hopedale Medical Complex - Hospital
Hopedale, Illinois, 61747, United States
Midwest Center for Hematology Oncology
Joliet, Illinois, 60432, United States
Joliet Oncology-Hematology Associates Limited
Joliet, Illinois, 60435, United States
Provena Saint Mary's Hospital
Kankakee, Illinois, 60901, United States
Kewanee Hospital
Kewanee, Illinois, 61443, United States
La Grange Memorial Hospital
La Grange, Illinois, 60525, United States
Deerpath Medical Associates
Lake Forest, Illinois, 60045, United States
North Shore Hematology Oncology
Libertyville, Illinois, 60048, United States
Mcdonough District Hospital
Macomb, Illinois, 61455, United States
Loyola University Medical Center
Maywood, Illinois, 60153, United States
Garneau, Stewart C MD (UIA Investigator)
Moline, Illinois, 61265, United States
Porubcin, Michael MD (UIA Investigator)
Moline, Illinois, 61265, United States
Sharis, Christine M MD (UIA Investigator)
Moline, Illinois, 61265, United States
Stoffel, Thomas J MD (UIA Investigator)
Moline, Illinois, 61265, United States
Trinity Medical Center
Moline, Illinois, 61265, United States
Vigliotti, Antonio, P.G. M.D. (UIA Investigator)
Moline, Illinois, 61265, United States
Good Samaritan Regional Medical Center
Mount Vernon, Illinois, 62864, United States
Hematology Oncology Consultants Limited
Naperville, Illinois, 60540, United States
Edward Hospital
Naperville, Illinois, 60566, United States
Cancer Care and Hematology Specialists of Chicagoland PC
Niles, Illinois, 60714, United States
Bromenn Regional Medical Center
Normal, Illinois, 61761, United States
Community Cancer Center Foundation
Normal, Illinois, 61761, United States
Advocate Christ Medical Center
Oak Lawn, Illinois, 60453-2699, United States
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, 61350, United States
Ottawa Regional Hospital and Healthcare Center
Ottawa, Illinois, 61350, United States
Pekin Cancer Treatment Center
Pekin, Illinois, 61554, United States
Pekin Hospital
Pekin, Illinois, 61554, United States
Methodist Medical Center of Illinois
Peoria, Illinois, 61603, United States
Proctor Hospital
Peoria, Illinois, 61614, United States
Illinois CancerCare-Peoria
Peoria, Illinois, 61615, United States
Illinois Oncology Research Association CCOP
Peoria, Illinois, 61615, United States
OSF Saint Francis Medical Center
Peoria, Illinois, 61637, United States
Illinois Valley Hospital
Peru, Illinois, 61354, United States
Perry Memorial Hospital
Princeton, Illinois, 61356, United States
West Suburban Cancer Center
River Forest, Illinois, 60305, United States
Swedish American Hospital
Rockford, Illinois, 61104, United States
Sarah Culbertson Memorial Hospital
Rushville, Illinois, 62681, United States
Edward H Kaplan MD and Associates
Skokie, Illinois, 60076, United States
Hematology Oncology Associates of Illinois - Skokie
Skokie, Illinois, 60076, United States
Midwest Cancer Research Group Incorporated
Skokie, Illinois, 60077, United States
Saint Margaret's Hospital
Spring Valley, Illinois, 61362, United States
Valley Cancer Center
Spring Valley, Illinois, 61362, United States
Memorial Medical Center
Springfield, Illinois, 62781-0001, United States
Carle Clinic-Urbana Main
Urbana, Illinois, 61801, United States
Carle Foundation dba Carle Cancer Center
Urbana, Illinois, 61801, United States
Saint Francis Hospital and Health Centers
Beech Grove, Indiana, 46107, United States
Elkhart General Hospital
Elkhart, Indiana, 46515, United States
Fort Wayne Medical Oncology and Hematology Inc - State Boulevard
Fort Wayne, Indiana, 46845, United States
Indiana University Medical Center
Indianapolis, Indiana, 46202, United States
Richard L. Roudebush Veterans Affairs Medical Center
Indianapolis, Indiana, 46202, United States
Wishard Hospital
Indianapolis, Indiana, 46202, United States
Saint Vincent Hospital and Health Services
Indianapolis, Indiana, 46260, United States
Howard Regional Healthcare System
Kokomo, Indiana, 46904, United States
Laporte Hospital
La Porte, Indiana, 46350, United States
Clarian Arnett Cancer Care
Lafayette, Indiana, 47904, United States
Premier Oncology Hematology Associates
Merrillville, Indiana, 46410, United States
Saint Anthony Memorial Health Center
Michigan City, Indiana, 46360, United States
Ball Memorial Hospital
Muncie, Indiana, 47303, United States
The Community Hospital
Munster, Indiana, 46321, United States
Reid Hospital and Health Care Services
Richmond, Indiana, 47374, United States
Memorial Hospital of South Bend
South Bend, Indiana, 46601, United States
Northern Indiana Cancer Research Consortium
South Bend, Indiana, 46601, United States
Saint Joseph's Medical Center
South Bend, Indiana, 46617, United States
South Bend Clinic
South Bend, Indiana, 46617, United States
McFarland Clinic
Ames, Iowa, 50010, United States
Constantinou, Costas L MD (UIA Investigator)
Bettendorf, Iowa, 52722, United States
Hematology Oncology Associates-Quad Cities
Bettendorf, Iowa, 52722, United States
Saint Anthony Regional Hospital
Carroll, Iowa, 51401, United States
Iowa Blood and Cancer Care PLC
Cedar Rapids, Iowa, 52402, United States
Saint Luke's Hospital
Cedar Rapids, Iowa, 52402, United States
Cedar Rapids Oncology Association
Cedar Rapids, Iowa, 52403, United States
Mercy Hospital
Cedar Rapids, Iowa, 52403, United States
Oncology Associates
Cedar Rapids, Iowa, 52403, United States
Medical Oncology and Hematology Associates-West Des Moines
Clive, Iowa, 50325, United States
Alegent Health Mercy Hospital
Council Bluffs, Iowa, 51503, United States
Genesis Medical Center - East Campus
Davenport, Iowa, 52803, United States
Genesis Medical Center - West Campus
Davenport, Iowa, 52804, United States
Mercy Capitol
Des Moines, Iowa, 50307, United States
Iowa Methodist Medical Center
Des Moines, Iowa, 50309, United States
Iowa Oncology Research Association CCOP
Des Moines, Iowa, 50309, United States
Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa, 50309, United States
Medical Oncology and Hematology Associates
Des Moines, Iowa, 50314, United States
Mercy Medical Center - Des Moines
Des Moines, Iowa, 50314, United States
Iowa Lutheran Hospital
Des Moines, Iowa, 50316, United States
Finley Hospital
Dubuque, Iowa, 52001, United States
University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242, United States
Mercy Medical Center - North Iowa
Mason City, Iowa, 50401, United States
Community Memorial Hospital
Missouri Valley, Iowa, 51555, United States
Burgess Memorial Hospital
Onawa, Iowa, 51040, United States
Siouxland Regional Cancer Center
Sioux City, Iowa, 51101-1733, United States
Siouxland Hematology - Oncology Associates
Sioux City, Iowa, 51101, United States
Mercy Medical Center-Sioux City
Sioux City, Iowa, 51104, United States
Saint Luke's Regional Medical Center
Sioux City, Iowa, 51104, United States
Covenant Medical Center
Waterloo, Iowa, 50702, United States
Memorial Hospital of Arkansas City
Arkansas City, Kansas, 67005, United States
Cancer Center of Kansas - Chanute
Chanute, Kansas, 66720, United States
Cancer Center of Kansas - Dodge City
Dodge City, Kansas, 67801, United States
Cancer Center of Kansas - El Dorado
El Dorado, Kansas, 67042, United States
Cancer Center of Kansas-Independence
Independence, Kansas, 67301, United States
Providence Medical Center
Kansas City, Kansas, 66112, United States
University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
Cancer Center of Kansas-Kingman
Kingman, Kansas, 67068, United States
Lawrence Memorial Hospital
Lawrence, Kansas, 66044, United States
Cancer Center of Kansas - McPherson
McPherson, Kansas, 67460, United States
Cancer Center of Kansas - Newton
Newton, Kansas, 67114, United States
Olathe Medical Center
Olathe, Kansas, 66061, United States
Cancer Center of Kansas - Ottawa
Ottawa, Kansas, 66067, United States
Menorah Medical Center
Overland Park, Kansas, 66209, United States
Radiation Oncology Practice Corporation Southwest
Overland Park, Kansas, 66210, United States
Cancer Center of Kansas - Parsons
Parsons, Kansas, 67357, United States
Mount Carmel Regional Cancer Center
Pittsburg, Kansas, 66762, United States
Cancer Center of Kansas - Pratt
Pratt, Kansas, 67124, United States
Cancer Center of Kansas - Salina
Salina, Kansas, 67401, United States
Shawnee Mission Medical Center
Shawnee Mission, Kansas, 66204, United States
Stormont-Vail Regional Health Center
Topeka, Kansas, 66604, United States
Saint Francis Hospital and Medical Center - Topeka
Topeka, Kansas, 66606, United States
Cancer Center of Kansas - Wellington
Wellington, Kansas, 67152, United States
Associates In Womens Health
Wichita, Kansas, 67208, United States
Cancer Center of Kansas-Wichita Medical Arts Tower
Wichita, Kansas, 67208, United States
Cancer Center of Kansas - Main Office
Wichita, Kansas, 67214, United States
Via Christi Regional Medical Center
Wichita, Kansas, 67214, United States
Wichita CCOP
Wichita, Kansas, 67214, United States
Cancer Center of Kansas - Winfield
Winfield, Kansas, 67156, United States
Our Lady Bellefonte Hospital
Ashland, Kentucky, 41101, United States
Central Baptist Hospital
Lexington, Kentucky, 40503, United States
University of Louisville
Louisville, Kentucky, 40292, United States
Merle Mahr Cancer Center
Madisonville, Kentucky, 42431, United States
Baton Rouge General Medical Center
Baton Rouge, Louisiana, 70806, United States
Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana, 70809, United States
Ochsner Clinic Foundation-Baton Rouge
Baton Rouge, Louisiana, 70809, United States
DeSoto Regional Health System
Mansfield, Louisiana, 71052, United States
Metairie Oncologists
Metairie, Louisiana, 70006, United States
Louisiana State University Sciences Center- Monroe
Monroe, Louisiana, 71210, United States
Louisiana State University Health Science Center
New Orleans, Louisiana, 70112, United States
Medical Center of Louisiana
New Orleans, Louisiana, 70112, United States
Ochsner Clinic CCOP
New Orleans, Louisiana, 70121, United States
Ochsner Clinic Foundation
New Orleans, Louisiana, 70121, United States
Highland Clinic
Shreveport, Louisiana, 71105, United States
Louisiana State University
Shreveport, Louisiana, 71130, United States
Eastern Maine Medical Center
Bangor, Maine, 04401, United States
Anne Arundel Medical Center
Annapolis, Maryland, 21401, United States
Greater Baltimore Medical Center
Baltimore, Maryland, 21204, United States
The Union Memorial Hospital
Baltimore, Maryland, 21218, United States
Franklin Square Hospital Center
Baltimore, Maryland, 21237, United States
Good Samaritan Hospital of Maryland
Baltimore, Maryland, 21239, United States
Johns Hopkins University
Baltimore, Maryland, 21287-8936, United States
Union Hospital of Cecil County
Elkton, Maryland, 21921, United States
Frederick Memorial Hospital
Frederick, Maryland, 21701, United States
Washington County Hospital
Hagerstown, Maryland, 21740, United States
Associates in Oncology Hematology PC -Kensington
Kensington, Maryland, 20895, United States
Associates In Oncology Hematology PC-Rockville
Rockville, Maryland, 20878, United States
Beverly Hospital
Beverly, Massachusetts, 01915, United States
Massachusetts General Hospital Cancer Center
Boston, Massachusetts, 02114, United States
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
Dana-Farber Cancer Institute
Boston, Massachusetts, 02115, United States
Boston Medical Center
Boston, Massachusetts, 02118, United States
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
Caritas Saint Elizabeth's Medical Center
Brighton, Massachusetts, 02135-2997, United States
Addison Gilbert Hospital
Gloucester, Massachusetts, 01930, United States
Franklin Medical Center
Greenfield, Massachusetts, 01301, United States
Holyoke Medical Center
Holyoke, Massachusetts, 01040, United States
Lowell General Hospital
Lowell, Massachusetts, 01854, United States
Lawrence Memorial
Medford, Massachusetts, 02155, United States
Holy Family Hospital
Methuen, Massachusetts, 01844, United States
Metrowest Medical Center Incorporated
Natick, Massachusetts, 01760, United States
Norwood Hospital
Norwood, Massachusetts, 02062, United States
North Shore Medical Center Cancer Center
Peabody, Massachusetts, 01960, United States
Berkshire Hematology Oncology PC
Pittsfield, Massachusetts, 01201, United States
Commonwealth Hematology Oncology PC-Quincy
Quincy, Massachusetts, 02169, United States
South Shore Hospital
South Weymouth, Massachusetts, 02190, United States
Baystate Medical Center
Springfield, Massachusetts, 01199, United States
Morton Hospital and Medical Center
Taunton, Massachusetts, 02780, United States
Noble Hospital
Westfield, Massachusetts, 01085, United States
Bixby Medical Center
Adrian, Michigan, 49221, United States
Hickman Cancer Center
Adrian, Michigan, 49221, United States
Saint Joseph Mercy Hospital
Ann Arbor, Michigan, 48106-0995, United States
Michigan Cancer Research Consortium Community Clinical Oncology Program
Ann Arbor, Michigan, 48106, United States
Battle Creek Health System
Battle Creek, Michigan, 49017, United States
Bay Regional Medical Center
Bay City, Michigan, 48708, United States
Mecosta County Medical Center
Big Rapids, Michigan, 49307, United States
Oakwood Hospital
Dearborn, Michigan, 48123, United States
Wayne State University
Detroit, Michigan, 48202, United States
Saint John Hospital and Medical Center
Detroit, Michigan, 48236, United States
Michigan State University - Breslin Cancer Center
East Lansing, Michigan, 48824-1313, United States
Green Bay Oncology - Escanaba
Escanaba, Michigan, 49431, United States
Hurley Medical Center
Flint, Michigan, 48502, United States
Genesys Regional Medical Center
Flint, Michigan, 48532, United States
McLaren Regional Medical Center
Flint, Michigan, 48532, United States
Grand Rapids Clinical Oncology Program
Grand Rapids, Michigan, 49503, United States
Saint Mary's Health Care
Grand Rapids, Michigan, 49503, United States
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan, 49503, United States
Spectrum Health-Blodgett Campus
Grand Rapids, Michigan, 49506, United States
Holland Community Hospital
Holland, Michigan, 49423, United States
Green Bay Oncology - Iron Mountain
Iron Mountain, Michigan, 49801, United States
Allegiance Health
Jackson, Michigan, 49201, United States
Borgess Medical Center
Kalamazoo, Michigan, 49001, United States
Bronson Methodist Hospital
Kalamazoo, Michigan, 49007, United States
West Michigan Cancer Center
Kalamazoo, Michigan, 49007, United States
Kalamazoo Center for Medical Studies
Kalamazoo, Michigan, 49008, United States
Ingham Regional Medical Center
Lansing, Michigan, 48910, United States
Sparrow Hospital
Lansing, Michigan, 48912, United States
Lapeer Regional Hospital
Lapeer, Michigan, 48446, United States
Saint Mary Mercy Hospital
Livonia, Michigan, 48154, United States
Mid-Michigan Medical Center - Midland
Midland, Michigan, 48670, United States
Community Cancer Center of Monroe
Monroe, Michigan, 48162, United States
Mercy Memorial Hospital
Monroe, Michigan, 48162, United States
Mercy Health Partners-Hackley Campus
Muskegon, Michigan, 49442, United States
Mercy Health Partners-Mercy Campus
Muskegon, Michigan, 49443, United States
Northern Michigan Regional Hospital
Petoskey, Michigan, 49770, United States
Saint Joseph Mercy Oakland
Pontiac, Michigan, 48341-2985, United States
Saint Joseph Mercy Port Huron
Port Huron, Michigan, 48060, United States
William Beaumont Hospital
Royal Oak, Michigan, 48073, United States
Saint Mary's of Michigan
Saginaw, Michigan, 48601, United States
Lakeland Hospital
Saint Joseph, Michigan, 49085, United States
Providence Hospital
Southfield, Michigan, 48075, United States
Munson Medical Center
Traverse City, Michigan, 49684, United States
Saint John Macomb-Oakland Hospital
Warren, Michigan, 48093, United States
Metro Health Hospital
Wyoming, Michigan, 49519, United States
Harris, John Gilbert MD (UIA Investigator)
Alexandria, Minnesota, 56308, United States
Medini, Eitan MD (UIA Investigator)
Alexandria, Minnesota, 56308, United States
Merit Care Clinic Bemidji
Bemidji, Minnesota, 56601, United States
Brainerd Medical Center Inc
Brainerd, Minnesota, 56401, United States
Saint Joseph's Medical Center
Brainerd, Minnesota, 56401, United States
Fairview Ridges Hospital
Burnsville, Minnesota, 55337, United States
Mercy Hospital
Coon Rapids, Minnesota, 55433, United States
Duluth Clinic CCOP
Duluth, Minnesota, 55805, United States
Miller-Dwan Hospital
Duluth, Minnesota, 55805, United States
Saint Luke's Hospital of Duluth
Duluth, Minnesota, 55805, United States
Saint Mary's Medical Center
Duluth, Minnesota, 55805, United States
Fairview-Southdale Hospital
Edina, Minnesota, 55435, United States
Etzell, Paul S MD (UIA Investigator)
Fergus Falls, Minnesota, 56537, United States
Swenson, Wade II, MD (UIA Investigator)
Fergus Falls, Minnesota, 56537, United States
Unity Hospital
Fridley, Minnesota, 55432, United States
Hutchinson Area Health Care
Hutchinson, Minnesota, 55350, United States
Meeker County Memorial Hospital
Litchfield, Minnesota, 55355, United States
Immanuel-Saint Joseph Hospital-Mayo Health System
Mankato, Minnesota, 56002, United States
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, 55109, United States
Saint John's Hospital - Healtheast
Maplewood, Minnesota, 55109, United States
Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407, United States
Virginia Piper Cancer Institute
Minneapolis, Minnesota, 55407, United States
Hennepin County Medical Center
Minneapolis, Minnesota, 55415, United States
Minneapolis Veterans Medical Center
Minneapolis, Minnesota, 55417, United States
Chippewa County - Montevideo Hospital
Montevideo, Minnesota, 56265, United States
North Memorial Medical Health Center
Robbinsdale, Minnesota, 55422, United States
Mayo Clinic
Rochester, Minnesota, 55905, United States
CentraCare Clinic
Saint Cloud, Minnesota, 56303, United States
Saint Cloud Hospital
Saint Cloud, Minnesota, 56303, United States
Metro-Minnesota CCOP
Saint Louis Park, Minnesota, 55416, United States
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, 55416, United States
Regions Hospital
Saint Paul, Minnesota, 55101, United States
Saint Joseph's Hospital - Healtheast
Saint Paul, Minnesota, 55102, United States
United Hospital
Saint Paul, Minnesota, 55102, United States
Adult and Pediatric Urology PLLP
Sartell, Minnesota, 56377, United States
Saint Francis Regional Medical Center
Shakopee, Minnesota, 55379, United States
Ridgeview Medical Center
Waconia, Minnesota, 55387, United States
Rice Memorial Hospital
Willmar, Minnesota, 56201, United States
Minnesota Oncology and Hematology PA-Woodbury
Woodbury, Minnesota, 55125, United States
Woodwinds Health Campus
Woodbury, Minnesota, 55125, United States
Veterans Affairs Medical Center
Jackson, Mississippi, 39216, United States
Keesler Medical Center
Keesler Air Force Base, Mississippi, 39534, United States
Singing River Hospital
Pascagoula, Mississippi, 39581, United States
Southeast Missouri Hospital
Cape Girardeau, Missouri, 63701, United States
Saint Francis Medical Center
Cape Girardeau, Missouri, 63703, United States
Missouri Cancer Associates
Columbia, Missouri, 65201, United States
Independence Regional Health Center
Independence, Missouri, 64050, United States
Freeman Health System
Joplin, Missouri, 64804, United States
Saint John's Regional Medical Center
Joplin, Missouri, 64804, United States
Truman Medical Center
Kansas City, Missouri, 64108, United States
Saint Luke's Cancer Institute
Kansas City, Missouri, 64111, United States
Saint Luke's Hospital of Kansas City
Kansas City, Missouri, 64111, United States
Radiation Oncology Practice Corporation South
Kansas City, Missouri, 64114, United States
Saint Joseph Health Center
Kansas City, Missouri, 64114, United States
Liberty Radiation Oncology Clinic
Kansas City, Missouri, 64116, United States
North Kansas City Hospital
Kansas City, Missouri, 64116, United States
Kansas City Veterans Affairs Medical Center
Kansas City, Missouri, 64128, United States
Research Medical Center
Kansas City, Missouri, 64132, United States
Radiation Oncology Practice Corporation - North
Kansas City, Missouri, 64154, United States
Liberty Hospital
Liberty, Missouri, 64068, United States
Missouri Cancer Care PC - Saint Charles
Saint Charles, Missouri, 63301, United States
Heartland Regional Medical Center
Saint Joseph, Missouri, 64506, United States
Ozark Health Ventures LLC dba Cancer Research for The Ozarks Springfield
Springfield, Missouri, 65802, United States
Saint John's Hospital
Springfield, Missouri, 65804, United States
Cox Medical Center
Springfield, Missouri, 65807, United States
Saint Louis Cancer and Breast Institute
St Louis, Missouri, 63109, United States
Saint Louis University Hospital
St Louis, Missouri, 63110, United States
Washington University School of Medicine
St Louis, Missouri, 63110, United States
Saint Anthony's Medical Center
St Louis, Missouri, 63128, United States
Missouri Baptist Medical Center
St Louis, Missouri, 63131, United States
Christian Hospital Northeast - Northwest
St Louis, Missouri, 63136, United States
Center for Cancer Care and Research
St Louis, Missouri, 63141, United States
Saint John's Mercy Medical Center
St Louis, Missouri, 63141, United States
Saint Louis-Cape Girardeau CCOP
St Louis, Missouri, 63141, United States
Hematology-Oncology Centers of the Northern Rockies PC
Billings, Montana, 59101, United States
Montana Cancer Consortium CCOP
Billings, Montana, 59101, United States
Northern Rockies Radiation Oncology Center
Billings, Montana, 59101, United States
Saint Vincent Healthcare
Billings, Montana, 59101, United States
Billings Clinic
Billings, Montana, 59107-7000, United States
Deaconess Medical Center
Billings, Montana, 59107, United States
Bozeman Deaconess Cancer Center
Bozeman, Montana, 59715, United States
Bozeman Deaconess Hospital
Bozeman, Montana, 59715, United States
Internal Medicine of Bozeman
Bozeman, Montana, 59715, United States
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana, 59701, United States
Benefis Healthcare- Sletten Cancer Institute
Great Falls, Montana, 59405, United States
Berdeaux, Donald MD (UIA Investigator)
Great Falls, Montana, 59405, United States
Big Sky Oncology
Great Falls, Montana, 59405, United States
Great Falls Clinic
Great Falls, Montana, 59405, United States
Saint Peter's Community Hospital
Helena, Montana, 59601, United States
Glacier Oncology PLLC
Kalispell, Montana, 59901, United States
Kalispell Medical Oncology
Kalispell, Montana, 59901, United States
Kalispell Regional Medical Center
Kalispell, Montana, 59901, United States
Eastern Montana Cancer Center
Miles City, Montana, 59301, United States
Community Medical Hospital
Missoula, Montana, 59801, United States
Montana Cancer Specialists
Missoula, Montana, 59802, United States
Saint Patrick Hospital - Community Hospital
Missoula, Montana, 59802, United States
Fremont Area Medical Center
Fremont, Nebraska, 68025, United States
Saint Francis Medical Center
Grand Island, Nebraska, 68803, United States
Good Samaritan Hospital
Kearney, Nebraska, 68847, United States
Bryan LGH Medical Center West
Lincoln, Nebraska, 68502, United States
Bryan LGH Medical Center East
Lincoln, Nebraska, 68506, United States
Lincoln Medical Education Foundation Cancer Resource Center
Lincoln, Nebraska, 68510, United States
Saint Elizabeth Regional Medical Center
Lincoln, Nebraska, 68510, United States
Great Plains Regional Medical Center
North Platte, Nebraska, 69101, United States
Missouri Valley Cancer Consortium CCOP
Omaha, Nebraska, 68106, United States
Methodist Estabrook Cancer Center
Omaha, Nebraska, 68114, United States
Alegent Health Immanuel Medical Center
Omaha, Nebraska, 68122, United States
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, 68124, United States
Creighton University Medical Center
Omaha, Nebraska, 68131, United States
University of Nebraska Medical Center
Omaha, Nebraska, 68198-7830, United States
Midlands Community Hospital
Papillion, Nebraska, 68046, United States
University Medical Center of Southern Nevada
Las Vegas, Nevada, 89102, United States
Nevada Cancer Research Foundation CCOP
Las Vegas, Nevada, 89106, United States
Nevada Cancer Institute
Las Vegas, Nevada, 89135, United States
New Hampshire Oncology-Hematology PA
Concord, New Hampshire, 03301, United States
Columbia Parkland Medical Center
Derry, New Hampshire, 03038, United States
Exeter Hospital
Exeter, New Hampshire, 03833, United States
New Hampshire Oncology Hematology Associates
Hooksett, New Hampshire, 03106, United States
Cheshire Medical Center-Dartmouth-Hitchcock Keene
Keene, New Hampshire, 03431, United States
LRGHealthcare-Lakes Region General Hospital
Laconia, New Hampshire, 03246, United States
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, 03756, United States
Elliot Hospital
Manchester, New Hampshire, 03103, United States
Portsmouth Regional Hospital
Portsmouth, New Hampshire, 03802, United States
Ocean Medical Center
Brick, New Jersey, 08724, United States
Cooper Hospital University Medical Center
Camden, New Jersey, 08103, United States
Veterans Adminstration New Jersey Health Care System
East Orange, New Jersey, 07018-1095, United States
Englewood Hospital and Medical Center
Englewood, New Jersey, 07631, United States
Hunterdon Medical Center
Flemington, New Jersey, 08822, United States
CentraState Medical Center
Freehold, New Jersey, 07728, United States
Cancer Institute of New Jersey At Hamilton
Hamilton, New Jersey, 08690, United States
Saint Barnabas Medical Center
Livingston, New Jersey, 07039, United States
Monmouth Medical Center
Long Branch, New Jersey, 07740, United States
Mountainside Hospital
Montclair, New Jersey, 07042, United States
Morristown Memorial Hospital
Morristown, New Jersey, 07962, United States
Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County
Mount Holly, New Jersey, 08060, United States
Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903, United States
Warren Hospital
Phillipsburg, New Jersey, 08865, United States
Booker Cancer Center at Riverview Medical Center
Red Bank, New Jersey, 07701, United States
Somerset Medical Center
Somerville, New Jersey, 08876, United States
Sparta Cancer Treatment Center
Sparta, New Jersey, 07871, United States
Overlook Hospital
Summit, New Jersey, 07902, United States
South Jersey Healthcare
Vineland, New Jersey, 08360, United States
Virtua West Jersey Hospital Voorhees
Voorhees Township, New Jersey, 08043, United States
University of New Mexico at Lovelace Medical Center
Albuquerque, New Mexico, 87102, United States
Hematology Oncology Associates
Albuquerque, New Mexico, 87106, United States
University of New Mexico
Albuquerque, New Mexico, 87106, United States
New Mexico Oncology Hematology Consultants
Albuquerque, New Mexico, 87109, United States
Presbyterian Kaseman Hospital
Albuquerque, New Mexico, 87110, United States
Memorial Medical Center - Las Cruces
Las Cruces, New Mexico, 88011, United States
New Mexico Cancer Care Associates
Santa Fe, New Mexico, 87505, United States
Long Island College Hospital
Brooklyn, New York, 11201, United States
Veterans Affairs Western New York Health Care System-Buffalo
Buffalo, New York, 14215, United States
Roswell Park Cancer Institute
Buffalo, New York, 14263, United States
Mary Imogene Bassett Hospital
Cooperstown, New York, 13326, United States
Hematology Oncology Associates of Central New York
East Syracuse, New York, 13057, United States
Adirondack Cancer Center
Glens Falls, New York, 12801, United States
Catskill Regional Medical Center
Harris, New York, 12742, United States
Orange Regional Medical Center
Middletown, New York, 10940, United States
Winthrop University Hospital
Mineola, New York, 11501, United States
Beth Israel Medical Center
New York, New York, 10003, United States
New York University Langone Medical Center
New York, New York, 10016, United States
Saint Luke's Roosevelt Hospital Center - Saint Luke's Division
New York, New York, 10025, United States
Columbia University Medical Center
New York, New York, 10032, United States
Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
Nyack Hospital
Nyack, New York, 10960, United States
Highland Hospital
Rochester, New York, 14620, United States
Interlakes Foundation Inc-Rochester
Rochester, New York, 14623, United States
University of Rochester
Rochester, New York, 14642, United States
State University of New York Upstate Medical University
Syracuse, New York, 13210, United States
Albert Einstein College of Medicine
The Bronx, New York, 10461, United States
The North Division of Montefiore Medical Center
The Bronx, New York, 10466, United States
Montefiore Medical Center
The Bronx, New York, 10467-2490, United States
Faxton-Saint Luke's Healthcare
Utica, New York, 13502, United States
Dickstein Cancer Treatment Center
White Plains, New York, 10601, United States
Mission Hospitals Inc
Asheville, North Carolina, 28801, United States
Alamance Regional Medical Center
Burlington, North Carolina, 27216, United States
University of North Carolina
Chapel Hill, North Carolina, 27599, United States
Carolinas Medical Center
Charlotte, North Carolina, 28203, United States
Gaston Memorial Hospital
Gastonia, North Carolina, 28054, United States
Southeastern Medical Oncology Center
Goldsboro, North Carolina, 27534, United States
Wayne Memorial Hospital
Goldsboro, North Carolina, 27534, United States
Wayne Radiation Oncology
Goldsboro, North Carolina, 27534, United States
Margaret R Pardee Memorial Hospital
Hendersonville, North Carolina, 28791, United States
Kinston Medical Specialists PA
Kinston, North Carolina, 28501, United States
Rutherford Hospital
Rutherfordton, North Carolina, 28139, United States
Iredell Memorial Hospital
Statesville, North Carolina, 28677, United States
Marion L Shepard Cancer Center
Washington, North Carolina, 27889, United States
New Hanover Regional Medical Center
Wilmington, North Carolina, 28401, United States
Wilson Medical Center
Wilson, North Carolina, 27893, United States
Bismarck Cancer Center
Bismarck, North Dakota, 58501, United States
Medcenter One Health Systems
Bismarck, North Dakota, 58501, United States
Mid Dakota Clinic
Bismarck, North Dakota, 58501, United States
Saint Alexius Medical Center
Bismarck, North Dakota, 58501, United States
Veterans Administration Medical Center
Fargo, North Dakota, 58102, United States
Innovis Health South University
Fargo, North Dakota, 58103, United States
Meritcare Hospital
Fargo, North Dakota, 58122, United States
MeritCare Medical Group
Fargo, North Dakota, 58122, United States
Altru Cancer Center
Grand Forks, North Dakota, 58201, United States
Trinity Cancer Care Center
Minot, North Dakota, 58701, United States
Akron City Hospital
Akron, Ohio, 44304, United States
Akron General Medical Center
Akron, Ohio, 44307, United States
Summa Barberton Hospital
Barberton, Ohio, 44203, United States
Mary Rutan Hospital
Bellefontaine, Ohio, 43311, United States
The Boardman Cancer Center
Boardman, Ohio, 44512, United States
Wood County Oncology Center
Bowling Green, Ohio, 43402, United States
Mercy Medical Center
Canton, Ohio, 44708, United States
Aultman Health Foundation
Canton, Ohio, 44710, United States
Adena Regional Medical Center
Chillicothe, Ohio, 54601, United States
Case Western Reserve University
Cleveland, Ohio, 44106, United States
MetroHealth Medical Center
Cleveland, Ohio, 44109, United States
Cleveland Clinic Foundation
Cleveland, Ohio, 44195, United States
Ohio State University Medical Center
Columbus, Ohio, 43210, United States
Riverside Methodist Hospital
Columbus, Ohio, 43214, United States
Columbus CCOP
Columbus, Ohio, 43215, United States
Grant Medical Center
Columbus, Ohio, 43215, United States
Mount Carmel Health Center West
Columbus, Ohio, 43222, United States
Doctors Hospital
Columbus, Ohio, 43228, United States
Grandview Hospital
Dayton, Ohio, 45405, United States
Good Samaritan Hospital - Dayton
Dayton, Ohio, 45406, United States
Miami Valley Hospital
Dayton, Ohio, 45409, United States
Samaritan North Health Center
Dayton, Ohio, 45415, United States
Veteran Affairs Medical Center
Dayton, Ohio, 45428, United States
Dayton CCOP
Dayton, Ohio, 45429, United States
Grady Memorial Hospital
Delaware, Ohio, 43015, United States
Hematology Oncology Center Incorporated
Elyria, Ohio, 44035, United States
Blanchard Valley Hospital
Findlay, Ohio, 45840, United States
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, 45005-1066, United States
Fremont Memorial Hospital
Fremont, Ohio, 43420, United States
Wayne Hospital
Greenville, Ohio, 45331, United States
Cleveland Clinic Cancer Center Independence
Independence, Ohio, 44131, United States
Cole, Sharon, K. M.D. (UIA Investigator)
Kenton, Ohio, 43326, United States
Kettering Medical Center
Kettering, Ohio, 45429, United States
Fairfield Medical Center
Lancaster, Ohio, 43130, United States
Saint Rita's Medical Center
Lima, Ohio, 45801, United States
Lima Memorial Hospital
Lima, Ohio, 45804, United States
Mansfield General Hospital-MedCentral Health System
Mansfield, Ohio, 44903, United States
Marietta Memorial Hospital
Marietta, Ohio, 45750, United States
Northwest Ohio Oncology Center
Maumee, Ohio, 43537-1839, United States
Saint Luke's Hospital
Maumee, Ohio, 43537, United States
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
Maumee, Ohio, 43537, United States
Licking Memorial Hospital
Newark, Ohio, 43055, United States
Bayview Oncology Associates
Oregon, Ohio, 43616, United States
Saint Charles Hospital
Oregon, Ohio, 43616, United States
Cancer Care Center, Incorporated
Salem, Ohio, 44460, United States
Firelands Regional Medical Center
Sandusky, Ohio, 44870, United States
North Coast Cancer Care
Sandusky, Ohio, 44870, United States
Community Hospital Springfield
Springfield, Ohio, 45505, United States
Flower Memorial Hospital
Sylvania, Ohio, 43560, United States
Mercy Hospital of Tiffin
Tiffin, Ohio, 44883, United States
The Toledo Hospital
Toledo, Ohio, 43606, United States
Saint Vincent Mercy Medical Center
Toledo, Ohio, 43608, United States
University of Toledo
Toledo, Ohio, 43614, United States
Toledo Community Hospital Oncology Program CCOP
Toledo, Ohio, 43617, United States
Mercy Cancer Center at Saint Anne Mercy Hospital
Toledo, Ohio, 43623, United States
Toledo Clinic
Toledo, Ohio, 43623, United States
Upper Valley Medical Center
Troy, Ohio, 45373, United States
Saint Joseph Cancer Center
Warren, Ohio, 44484, United States
Fulton County Health Center
Wauseon, Ohio, 43567, United States
Saint Ann's Hospital
Westerville, Ohio, 43081, United States
Clinton Memorial Hospital
Wilmington, Ohio, 45177, United States
Cancer Treatment Center
Wooster, Ohio, 44691, United States
Cleveland Clinic Wooster Specialty Center
Wooster, Ohio, 44691, United States
Wright-Patterson Medical Center
Wright-Patterson Air Force Base, Ohio, 45433-5529, United States
Greene Memorial Hospital
Xenia, Ohio, 45385, United States
Saint Elizabeth Hospital Medical Center
Youngstown, Ohio, 44501, United States
Genesis HealthCare System
Zanesville, Ohio, 43701, United States
Cancer Centers of Southwest Oklahoma Research - Lawton
Lawton, Oklahoma, 73505, United States
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
Cancer Care Associates
Oklahoma City, Oklahoma, 73120, United States
Natalie W Bryant Cancer Center
Tulsa, Oklahoma, 74136, United States
Bay Area Hospital
Coos Bay, Oregon, 97420, United States
Legacy Mount Hood Medical Center
Gresham, Oregon, 97030, United States
Providence Milwaukie Hospital
Milwaukie, Oregon, 97222, United States
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, 97210, United States
Providence Portland Medical Center
Portland, Oregon, 97213, United States
Adventist Medical Center
Portland, Oregon, 97216, United States
Columbia River Oncology Program
Portland, Oregon, 97225, United States
Providence Saint Vincent Medical Center
Portland, Oregon, 97225, United States
Legacy Emanuel Hospital and Health Center
Portland, Oregon, 97227, United States
Northwest Cancer Specialists-Rose Quarter Cancer Center
Portland, Oregon, 97227, United States
Kaiser Permanente
Portland, Oregon, 97232, United States
Oregon Health and Science University
Portland, Oregon, 97239, United States
Salem Hospital
Salem, Oregon, 97309, United States
Legacy Meridian Park Hospital
Tualatin, Oregon, 97062, United States
Abington Memorial Hospital
Abington, Pennsylvania, 19001, United States
Lehigh Valley Hospital
Allentown, Pennsylvania, 18105, United States
Saint Luke's Hospital
Bethlehem, Pennsylvania, 18015, United States
Bryn Mawr Hospital
Bryn Mawr, Pennsylvania, 19010, United States
Marion Community Hospital
Carbondale, Pennsylvania, 18407, United States
Geisinger Medical Center
Danville, Pennsylvania, 17822-2001, United States
Mercy Fitzgerald Hospital
Darby, Pennsylvania, 19023-1291, United States
Doylestown Hospital
Doylestown, Pennsylvania, 18901, United States
Delaware County Memorial Hospital
Drexel Hill, Pennsylvania, 19026, United States
Pocono Medical Center
East Stroudsburg, Pennsylvania, 18301, United States
Easton Hospital
Easton, Pennsylvania, 18042, United States
Ephrata Cancer Center
Ephrata, Pennsylvania, 17522, United States
PinnacleHealth Regional Cancer Center at Polyclinic Hospital
Harrisburg, Pennsylvania, 17110, United States
Geisinger South Wilkes Barre-Hazelton Cancer Center
Hazleton, Pennsylvania, 18201, United States
Lancaster General Hospital
Lancaster, Pennsylvania, 17604, United States
Central PA Hematology-Medical Oncology Associates PC
Lemoyne, Pennsylvania, 17043, United States
Riddle Hospital
Media, Pennsylvania, 19063, United States
Paoli Memorial Hospital
Paoli, Pennsylvania, 19301, United States
Abramson Cancer Center of The University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
Pennsylvania Hospital
Philadelphia, Pennsylvania, 19107, United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111-2497, United States
Aria Health-Torresdale Campus
Philadelphia, Pennsylvania, 19114, United States
Albert Einstein Medical Center
Philadelphia, Pennsylvania, 19141, United States
Allegheny Cancer Center at Allegheny General Hospital
Pittsburgh, Pennsylvania, 15212, United States
University of Pittsburgh
Pittsburgh, Pennsylvania, 15213, United States
Western Pennsylvania Hospital
Pittsburgh, Pennsylvania, 15224-1791, United States
Pottstown Memorial Medical Center
Pottstown, Pennsylvania, 19464, United States
Saint Joseph Medical Center
Reading, Pennsylvania, 19605, United States
Guthrie Clinic - Sayre
Sayre, Pennsylvania, 18840, United States
Mercy Hospital
Scranton, Pennsylvania, 18501, United States
Hematology and Oncology Associates of North East Pennsylvania
Scranton, Pennsylvania, 18508, United States
Community Medical Center
Scranton, Pennsylvania, 18510, United States
Moses Taylor Hospital
Scranton, Pennsylvania, 18510, United States
Scranton Hematology Oncology
Scranton, Pennsylvania, 18510, United States
Grand View Hospital
Sellersville, Pennsylvania, 18960, United States
Geisinger Medical Group
State College, Pennsylvania, 16801, United States
Mount Nittany Medical Center
State College, Pennsylvania, 16803, United States
Associates In Hematology Oncology PC-Upland
Upland, Pennsylvania, 19013, United States
Jennersville Regional Hospital
West Grove, Pennsylvania, 19390, United States
Reading Hospital and Medical Center
West Reading, Pennsylvania, 19612, United States
Geisinger Wyoming Valley
Wilkes-Barre, Pennsylvania, 18711, United States
Lankenau Hospital
Wynnewood, Pennsylvania, 19096, United States
Mainline Health CCOP
Wynnewood, Pennsylvania, 19096, United States
Hematology and Oncology Associates of Rhode Island Inc
Cranston, Rhode Island, 02920, United States
Rhode Island Hospital
Providence, Rhode Island, 02903, United States
Miriam Hospital
Providence, Rhode Island, 02906, United States
Kent County Hospital
Warwick, Rhode Island, 02886, United States
AnMed Health Hospital
Anderson, South Carolina, 29621, United States
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
Greenville Memorial Hospital
Greenville, South Carolina, 29605, United States
Greenville CCOP
Greenville, South Carolina, 29615, United States
Spartanburg Regional Medical Center
Spartanburg, South Carolina, 29303, United States
Upstate Carolina CCOP
Spartanburg, South Carolina, 29303, United States
Conklin Regional Cancer Center
Aberdeen, South Dakota, 57401, United States
Rapid City Regional Hospital
Rapid City, South Dakota, 57701, United States
Sanford Cancer Center-Oncology Clinic
Sioux Falls, South Dakota, 57104, United States
Avera Cancer Institute
Sioux Falls, South Dakota, 57105, United States
Avera McKennan Hospital and University Health Center
Sioux Falls, South Dakota, 57105, United States
Medical X-Ray Center
Sioux Falls, South Dakota, 57105, United States
Sanford University of South Dakota Medical Center
Sioux Falls, South Dakota, 57117-5134, United States
Wellmont Holston Valley Hospital and Medical Center
Kingsport, Tennessee, 37660, United States
Thompson Cancer Survival Center
Knoxville, Tennessee, 37916, United States
Veterans Affairs Medical Center - Memphis
Memphis, Tennessee, 38104, United States
Tennessee Oncology PLLC- Centennial Medical Center
Nashville, Tennessee, 37203, United States
Meharry Medical College
Nashville, Tennessee, 37208-3599, United States
Vanderbilt University
Nashville, Tennessee, 37232, United States
The Don and Sybil Harrington Cancer Center
Amarillo, Texas, 79106, United States
Texas Health Presbyterian Hospital Dallas
Dallas, Texas, 75231, United States
The Center for Integrative Cancer Medicine
El Paso, Texas, 79902, United States
Brooke Army Medical Center
Fort Sam Houston, Texas, 78234, United States
University of Texas Medical Branch
Galveston, Texas, 77555-0565, United States
Baylor College of Medicine
Houston, Texas, 77030, United States
Ben Taub General Hospital
Houston, Texas, 77030, United States
Methodist Hospital
Houston, Texas, 77030, United States
Saint Luke's Episcopal Hospital
Houston, Texas, 77030, United States
Veterans Administration Medical Center
Houston, Texas, 77030, United States
Wilford Hall Medical Center
Lackland Air Force Base, Texas, 78236, United States
Doctor's Hospital of Laredo
Laredo, Texas, 78041, United States
Audie L Murphy Veterans Affairs Hospital
San Antonio, Texas, 78209, United States
University of Texas Health Science Center
San Antonio, Texas, 78229-3900, United States
Cancer Therapy and Research Center at The UT Health Science Center at San Antonio
San Antonio, Texas, 78229, United States
South Texas Oncology and Hematology PA
San Antonio, Texas, 78229, United States
University Hospital
San Antonio, Texas, 78229, United States
Scott and White Memorial Hospital
Temple, Texas, 76508, United States
Southwestern Oncology Research Department
Bennington, Vermont, 05201, United States
University of Vermont
Burlington, Vermont, 05401, United States
Danville Regional Medical Center
Danville, Virginia, 24541, United States
Fredericksburg Oncology Inc
Fredericksburg, Virginia, 22401, United States
Riverside Middle Peninsula Cancer Center
Gloucester, Virginia, 23061, United States
Lynchburg Hematology-Oncology Clinic
Lynchburg, Virginia, 24501, United States
Peninsula Cancer Institute-Newport News
Newport News, Virginia, 23601, United States
Southwest VA Regional Cancer Center
Norton, Virginia, 24273, United States
Peninsula Cancer Institute
Williamsburg, Virginia, 23185, United States
Auburn Regional Medical Center
Auburn, Washington, 98002, United States
Saint Joseph Hospital
Bellingham, Washington, 98225, United States
Harrison Bremerton Hematology and Oncology
Bremerton, Washington, 98310, United States
Providence Centralia Hospital
Centralia, Washington, 98531, United States
Saint Francis Hospital
Federal Way, Washington, 98003, United States
Columbia Basin Hematology and Oncology PLLC
Kennewick, Washington, 99336, United States
Evergreen Hospital Medical Center
Kirkland, Washington, 98033, United States
Providence - Saint Peter Hospital
Olympia, Washington, 98506-5166, United States
Capital Medical Center
Olympia, Washington, 98507, United States
Olympic Medical Center
Port Angeles, Washington, 98362, United States
Good Samaritan Community Hospital
Puyallup, Washington, 98372, United States
Valley Medical Center
Renton, Washington, 98055, United States
Virginia Mason CCOP
Seattle, Washington, 98101, United States
Minor and James Medical PLLC
Seattle, Washington, 98104, United States
Puget Sound Oncology Consortium
Seattle, Washington, 98109, United States
Group Health Cooperative
Seattle, Washington, 98112, United States
Swedish Medical Center-First Hill
Seattle, Washington, 98122-4307, United States
The Polyclinic
Seattle, Washington, 98122, United States
University of Washington Medical Center
Seattle, Washington, 98195, United States
Cancer Care Northwest - Spokane South
Spokane, Washington, 99202, United States
Sacred Heart Medical Center
Spokane, Washington, 99204, United States
Holy Family Hospital
Spokane, Washington, 99207, United States
Allenmore Hospital
Tacoma, Washington, 98405, United States
Northwest CCOP
Tacoma, Washington, 98405, United States
Saint Joseph Medical Center
Tacoma, Washington, 98405, United States
Tacoma General Hospital
Tacoma, Washington, 98405, United States
Multicare Health System
Tacoma, Washington, 98415, United States
Saint Clare Hospital
Tacoma, Washington, 98499, United States
Southwest Washington Medical Center
Vancouver, Washington, 98668, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima, Washington, 98902, United States
Edwards Comprehensive Cancer Center
Huntington, West Virginia, 25701, United States
West Virginia University
Morgantown, West Virginia, 26506, United States
Camden-Clark Memorial Hospital
Parkersburg, West Virginia, 26101, United States
Princeton Community Hospital
Princeton, West Virginia, 24740, United States
Wheeling Hospital
Wheeling, West Virginia, 26003, United States
Langlade Hospital and Cancer Center
Antigo, Wisconsin, 54409, United States
Marshfield Clinic Cancer Care at Regional Cancer Center
Eau Claire, Wisconsin, 54701, United States
Sacred Heart Hospital
Eau Claire, Wisconsin, 54701, United States
Midelfort Clinic-Clairemont Campus
Eau Claire, Wisconsin, 54702, United States
Mayo Clinic Health System Eau Claire Hospital - Luther Campus
Eau Claire, Wisconsin, 54703, United States
Central Wisconsin Cancer Program
Fond du Lac, Wisconsin, 54935, United States
Green Bay Oncology at Saint Vincent Hospital
Green Bay, Wisconsin, 54301-3526, United States
Saint Vincent Hospital
Green Bay, Wisconsin, 54301, United States
Green Bay Oncology Limited at Saint Mary's Hospital
Green Bay, Wisconsin, 54303, United States
Saint Mary's Hospital
Green Bay, Wisconsin, 54303, United States
Aurora BayCare Medical Center
Green Bay, Wisconsin, 54311-6519, United States
Mercy Health System
Janesville, Wisconsin, 53547, United States
UW Cancer Center Johnson Creek
Johnson Creek, Wisconsin, 53038, United States
Franciscan Skemp Healthcare
La Crosse, Wisconsin, 54601, United States
UW Health Oncology - 1 South Park
Madison, Wisconsin, 53715, United States
Dean Hematology and Oncology Clinic
Madison, Wisconsin, 53717, United States
University of Wisconsin Hospital and Clinics
Madison, Wisconsin, 53792, United States
Bay Area Medical Center
Marinette, Wisconsin, 54143, United States
Vince Lombardi Cancer Clinic-Marinette
Marinette, Wisconsin, 54143, United States
Marshfield Clinic
Marshfield, Wisconsin, 54449, United States
Saint Joseph's Hospital
Marshfield, Wisconsin, 54449, United States
Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin, 54548, United States
Oconomowoc Memorial Hospital-ProHealth Care Inc
Oconomowoc, Wisconsin, 53066-3896, United States
Green Bay Oncology - Oconto Falls
Oconto Falls, Wisconsin, 54154, United States
Marshfield Clinic at James Beck Cancer Center
Rhinelander, Wisconsin, 54501, United States
Marshfield Clinic-Rice Lake Center
Rice Lake, Wisconsin, 54868, United States
Saint Michael's Hospital
Stevens Point, Wisconsin, 54481, United States
Green Bay Oncology - Sturgeon Bay
Sturgeon Bay, Wisconsin, 54235, United States
Waukesha Memorial Hospital
Waukesha, Wisconsin, 53188, United States
Aspirus Regional Cancer Center
Wausau, Wisconsin, 54401, United States
Marshfield Clinic-Wausau Center
Wausau, Wisconsin, 54401, United States
Diagnostic and Treatment Center
Weston, Wisconsin, 54476, United States
Marshfield Clinic - Weston Center
Weston, Wisconsin, 54476, United States
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin, 54494, United States
Welch Cancer Center
Sheridan, Wyoming, 82801, United States
Tom Baker Cancer Centre
Calgary, Alberta, T2N 4N2, Canada
Cross Cancer Institute
Edmonton, Alberta, T6G 1Z2, Canada
Lions Gate Hospital
North Vancouver, British Columbia, V7L 2L7, Canada
BCCA-Fraser Valley Cancer Centre
Surrey, British Columbia, V3V 1Z2, Canada
BCCA-Vancouver Cancer Centre
Vancouver, British Columbia, V5Z 4E6, Canada
CancerCare Manitoba
Winnipeg, Manitoba, R3E 0V9, Canada
The Moncton Hospital
Moncton, New Brunswick, E1C 6Z8, Canada
Atlantic Health Sciences Corporation-Saint John Regional Hospital
Saint John, New Brunswick, E2L 4L2, Canada
The Royal Victoria Hospital
Barrie, Ontario, L4M 6M2, Canada
Cambridge Memorial Hospital
Cambridge, Ontario, N1R 3G2, Canada
Regional Cancer Program of The Hopital Regional de Sudbury Regional Hopital
Greater Sudbury, Ontario, P3E 5J1, Canada
Juravinski Cancer Centre at Hamilton Health Sciences
Hamilton, Ontario, L8V 5C2, Canada
Cancer Centre of Southeastern Ontario at Kingston General Hospital
Kingston, Ontario, K7L 5P9, Canada
Grand River Regional Cancer Centre at Grand River Hospital
Kitchener, Ontario, N2G 1G3, Canada
London Regional Cancer Program
London, Ontario, N6A 4L6, Canada
Credit Valley Hospital
Mississauga, Ontario, L5M 2N1, Canada
Ottawa Health Research Institute-General Division
Ottawa, Ontario, K1H 1C4, Canada
Algoma District Cancer Program Sault Area Hospital
Sault Ste. Marie, Ontario, P6A 3C4, Canada
Niagara Health System-Saint Catharines General
St. Catharines, Ontario, L2R 2Z7, Canada
Thunder Bay Regional Health Science Centre
Thunder Bay, Ontario, P7B 6V4, Canada
Toronto East General Hospital
Toronto, Ontario, M4C 3E7, Canada
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5, Canada
Saint Michael's Hospital
Toronto, Ontario, M5B 1W8, Canada
Mount Sinai Hospital
Toronto, Ontario, M5G 1X5, Canada
University Health Network-Princess Margaret Hospital
Toronto, Ontario, M5G 2M9, Canada
Trillium Health Centre-West Toronto
Toronto, Ontario, M9C 1A5, Canada
Windsor Regional Cancer Centre
Windsor, Ontario, N8W 2X3, Canada
PEI Cancer Treatment Centre-Queen Elizabeth Hospital
Charlottetown, Prince Edward Island, C1A 8T5, Canada
McGill University Department of Oncology
Montreal, Quebec, H2W 1S6, Canada
Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1, Canada
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4, Canada
Andres Grillasca Hospital
Ponce, 00733, Puerto Rico
Hato Rey Hematology Oncology Group
San Juan, 00917, Puerto Rico
I Gonzales Martinez-Oncologic Hospital
San Juan, 00919, Puerto Rico
San Juan Veterans Affairs Medical Center
San Juan, 00921-3201, Puerto Rico
San Juan City Hospital
San Juan, 00928, Puerto Rico
Related Publications (12)
Gallois C, Shi Q, Meyers JP, Iveson T, Alberts SR, de Gramont A, Sobrero AF, Haller DG, Oki E, Shields AF, Goldberg RM, Kerr R, Lonardi S, Yothers G, Kelly C, Boukovinas I, Labianca R, Sinicrope FA, Souglakos I, Yoshino T, Meyerhardt JA, Andre T, Papamichael D, Taieb J. Prognostic Impact of Early Treatment and Oxaliplatin Discontinuation in Patients With Stage III Colon Cancer: An ACCENT/IDEA Pooled Analysis of 11 Adjuvant Trials. J Clin Oncol. 2023 Feb 1;41(4):803-815. doi: 10.1200/JCO.21.02726. Epub 2022 Oct 28.
PMID: 36306483DERIVEDSaberzadeh-Ardestani B, Foster NR, Lee HE, Shi Q, Alberts SR, Smyrk TC, Sinicrope FA. Association of tumor-infiltrating lymphocytes with survival depends on primary tumor sidedness in stage III colon cancers (NCCTG N0147) [Alliance]. Ann Oncol. 2022 Nov;33(11):1159-1167. doi: 10.1016/j.annonc.2022.07.1942. Epub 2022 Aug 10.
PMID: 35963480DERIVEDAzizi Z, Zheng C, Mosquera L, Pilote L, El Emam K; GOING-FWD Collaborators. Can synthetic data be a proxy for real clinical trial data? A validation study. BMJ Open. 2021 Apr 16;11(4):e043497. doi: 10.1136/bmjopen-2020-043497.
PMID: 33863713DERIVEDCohen R, Taieb J, Fiskum J, Yothers G, Goldberg R, Yoshino T, Alberts S, Allegra C, de Gramont A, Seitz JF, O'Connell M, Haller D, Wolmark N, Erlichman C, Zaniboni A, Lonardi S, Kerr R, Grothey A, Sinicrope FA, Andre T, Shi Q. Microsatellite Instability in Patients With Stage III Colon Cancer Receiving Fluoropyrimidine With or Without Oxaliplatin: An ACCENT Pooled Analysis of 12 Adjuvant Trials. J Clin Oncol. 2021 Feb 20;39(6):642-651. doi: 10.1200/JCO.20.01600. Epub 2020 Dec 23.
PMID: 33356421DERIVEDLabadie JD, Hua X, Harrison TA, Banbury BL, Huyghe JR, Sun W, Shi Q, Yothers G, Alberts SR, Sinicrope FA, Goldberg RM, George TJ, Penney KL, Phipps AI, Cohen SA, Peters U, Chan AT, Newcomb PA. Genetic Predictors of Severe Skin Toxicity in Patients with Stage III Colon Cancer Treated with Cetuximab: NCCTG N0147 (Alliance). Cancer Epidemiol Biomarkers Prev. 2021 Feb;30(2):404-411. doi: 10.1158/1055-9965.EPI-20-1274. Epub 2020 Nov 17.
PMID: 33203692DERIVEDLee H, Sha D, Foster NR, Shi Q, Alberts SR, Smyrk TC, Sinicrope FA. Analysis of tumor microenvironmental features to refine prognosis by T, N risk group in patients with stage III colon cancer (NCCTG N0147) (Alliance). Ann Oncol. 2020 Apr;31(4):487-494. doi: 10.1016/j.annonc.2020.01.011. Epub 2020 Jan 25.
PMID: 32165096DERIVEDPenney KL, Banbury BL, Bien S, Harrison TA, Hua X, Phipps AI, Sun W, Song M, Joshi AD, Alberts SR, Allegra CJ, Atkins J, Colangelo LH, George TJ, Goldberg RM, Lucas PC, Nair SG, Shi Q, Sinicrope FA, Wolmark N, Yothers G, Peters U, Newcomb PA, Chan AT. Genetic Variant Associated With Survival of Patients With Stage II-III Colon Cancer. Clin Gastroenterol Hepatol. 2020 Nov;18(12):2717-2723.e3. doi: 10.1016/j.cgh.2019.11.046. Epub 2019 Dec 4.
PMID: 31811950DERIVEDTaieb J, Shi Q, Pederson L, Alberts S, Wolmark N, Van Cutsem E, de Gramont A, Kerr R, Grothey A, Lonardi S, Yoshino T, Yothers G, Sinicrope FA, Zaanan A, Andre T. Prognosis of microsatellite instability and/or mismatch repair deficiency stage III colon cancer patients after disease recurrence following adjuvant treatment: results of an ACCENT pooled analysis of seven studies. Ann Oncol. 2019 Sep 1;30(9):1466-1471. doi: 10.1093/annonc/mdz208.
PMID: 31268130DERIVEDZaanan A, Shi Q, Taieb J, Alberts SR, Meyers JP, Smyrk TC, Julie C, Zawadi A, Tabernero J, Mini E, Goldberg RM, Folprecht G, Van Laethem JL, Le Malicot K, Sargent DJ, Laurent-Puig P, Sinicrope FA. Role of Deficient DNA Mismatch Repair Status in Patients With Stage III Colon Cancer Treated With FOLFOX Adjuvant Chemotherapy: A Pooled Analysis From 2 Randomized Clinical Trials. JAMA Oncol. 2018 Mar 1;4(3):379-383. doi: 10.1001/jamaoncol.2017.2899.
PMID: 28983557DERIVEDSinicrope FA, Shi Q, Allegra CJ, Smyrk TC, Thibodeau SN, Goldberg RM, Meyers JP, Pogue-Geile KL, Yothers G, Sargent DJ, Alberts SR. Association of DNA Mismatch Repair and Mutations in BRAF and KRAS With Survival After Recurrence in Stage III Colon Cancers : A Secondary Analysis of 2 Randomized Clinical Trials. JAMA Oncol. 2017 Apr 1;3(4):472-480. doi: 10.1001/jamaoncol.2016.5469.
PMID: 28006055DERIVEDSticca RP, Alberts SR, Mahoney MR, Sargent DJ, Finstuen LM, Nelson GD, Husted TM, Franko J, Goldman CD, Pockaj BA. Current use and surgical efficacy of laparoscopic colectomy in colon cancer. J Am Coll Surg. 2013 Jul;217(1):56-62; discussion 62-3. doi: 10.1016/j.jamcollsurg.2013.02.023. Epub 2013 Apr 24.
PMID: 23623224DERIVEDAlberts SR, Sargent DJ, Nair S, Mahoney MR, Mooney M, Thibodeau SN, Smyrk TC, Sinicrope FA, Chan E, Gill S, Kahlenberg MS, Shields AF, Quesenberry JT, Webb TA, Farr GH Jr, Pockaj BA, Grothey A, Goldberg RM. Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial. JAMA. 2012 Apr 4;307(13):1383-93. doi: 10.1001/jama.2012.385.
PMID: 22474202DERIVED
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Limitations and Caveats
Accrual to arms A and D terminated early based on the results of the planned 2nd interim analysis. Sample sizes limit statistical conclusions for data from the irinotecan treated patients as those treatment arms were discontinued early in the study.
Results Point of Contact
- Title
- Dr. Steven Alberts
- Organization
- North Central Cancer Treatment Group
Study Officials
- PRINCIPAL INVESTIGATOR
Steven A Alberts, MD
North Central Cancer Treatment Group
Publication Agreements
- PI is Sponsor Employee
- No
- Restriction Type
- LTE60
- Restrictive Agreement
- Yes
Study Design
- Study Type
- interventional
- Phase
- phase 3
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- NIH
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 8, 2004
First Posted
March 10, 2004
Study Start
February 1, 2004
Primary Completion
November 1, 2012
Study Completion
November 1, 2012
Last Updated
May 13, 2020
Results First Posted
February 9, 2015
Record last verified: 2020-04