Success Metrics

Clinical Success Rate
78.9%

Based on 500 completed trials

Completion Rate
79%(500/634)
Active Trials
268(23%)
Results Posted
53%(266 trials)
Terminated
134(11%)

Phase Distribution

Ph phase_1
280
24%
Ph phase_3
195
16%
Ph phase_4
11
1%
Ph early_phase_1
7
1%
Ph phase_2
659
55%
Ph not_applicable
22
2%

Phase Distribution

287

Early Stage

659

Mid Stage

206

Late Stage

Phase Distribution1174 total trials
Early Phase 1First-in-human
7(0.6%)
Phase 1Safety & dosage
280(23.9%)
Phase 2Efficacy & side effects
659(56.1%)
Phase 3Large-scale testing
195(16.6%)
Phase 4Post-market surveillance
11(0.9%)
N/ANon-phased studies
22(1.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.9%

500 of 668 finished

Non-Completion Rate

25.1%

168 ended early

Currently Active

268

trials recruiting

Total Trials

1,188

all time

Status Distribution
Active(335)
Completed(500)
Terminated(168)
Other(185)

Detailed Status

Completed500
unknown183
Recruiting173
Terminated134
Active, not recruiting95
Not yet recruiting65

Development Timeline

Analytics

Development Status

Total Trials
1188
Active
268
Success Rate
78.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (0.6%)
Phase 1280 (23.9%)
Phase 2659 (56.1%)
Phase 3195 (16.6%)
Phase 411 (0.9%)
N/A22 (1.9%)

Trials by Status

terminated13411%
completed50042%
enrolling_by_invitation20%
recruiting17315%
not_yet_recruiting655%
suspended20%
withdrawn343%
active_not_recruiting958%
unknown18315%

Recent Activity

Clinical Trials (1,188)

Showing 20 of 1,188 trialsScroll for more
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT06820463Phase 2

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Recruiting
NCT07490301Phase 2

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT06109467Phase 2

Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer

Active Not Recruiting
NCT06780111Phase 1

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Recruiting
NCT04379596Phase 2

Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)

Recruiting
NCT05235542Phase 1

A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors

Completed
NCT03321643Phase 1

Testing the Addition of an Immunotherapy Agent, Atezolizumab, When Given With the Usual Chemo-Immunotherapy Drug Combination (Rituximab Plus Gemcitabine and Oxaliplatin) for Relapsed/Refractory (That Has Come Back or Not Responded to Treatment) Transformed Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT04607421Phase 3

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Active Not Recruiting
NCT05083481Phase 1

A Study of ASP1570 Taken by Itself, or ASP1570 Taken Together With Either Pembrolizumab, Standard Therapies, or Both, in Adults With Solid Tumors

Terminated
NCT05365581Phase 1

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Recruiting
NCT06884670Phase 2

Assessment of Efficacy and Safety of PD-1 Monoclonal Antibody Combined With IL-2 and CapeOX in Neoadjuvant Therapy for Locally Advanced Rectal Cancer Prior to Surgery: A Prospective, Multi-center, Randomized Controlled Study

Completed
NCT06205485Phase 3

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

Recruiting
NCT06997497Phase 3

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Recruiting
NCT07214298Phase 1

Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT05379595Phase 1

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Recruiting
NCT06662786Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Recruiting
NCT07059611Phase 2

Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma

Not Yet Recruiting
NCT05355701Phase 1

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Recruiting
NCT06901531Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,188