Success Metrics

Clinical Success Rate
78.6%

Based on 512 completed trials

Completion Rate
79%(512/651)
Active Trials
281(23%)
Results Posted
54%(274 trials)
Terminated
139(11%)

Phase Distribution

Ph early_phase_1
7
1%
Ph phase_2
674
55%
Ph not_applicable
23
2%
Ph phase_4
14
1%
Ph phase_1
292
24%
Ph phase_3
200
16%

Phase Distribution

299

Early Stage

674

Mid Stage

214

Late Stage

Phase Distribution1210 total trials
Early Phase 1First-in-human
7(0.6%)
Phase 1Safety & dosage
292(24.1%)
Phase 2Efficacy & side effects
674(55.7%)
Phase 3Large-scale testing
200(16.5%)
Phase 4Post-market surveillance
14(1.2%)
N/ANon-phased studies
23(1.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.7%

512 of 685 finished

Non-Completion Rate

25.3%

173 ended early

Currently Active

281

trials recruiting

Total Trials

1,224

all time

Status Distribution
Active(357)
Completed(512)
Terminated(173)
Other(182)

Detailed Status

Completed512
Recruiting180
unknown179
Terminated139
Active, not recruiting101
Not yet recruiting74

Development Timeline

Analytics

Development Status

Total Trials
1224
Active
281
Success Rate
78.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (0.6%)
Phase 1292 (24.1%)
Phase 2674 (55.7%)
Phase 3200 (16.5%)
Phase 414 (1.2%)
N/A23 (1.9%)

Trials by Status

completed51242%
not_yet_recruiting746%
terminated13911%
withdrawn343%
unknown17915%
enrolling_by_invitation20%
suspended30%
active_not_recruiting1018%
recruiting18015%

Recent Activity

Clinical Trials (1,224)

Showing 20 of 1,224 trialsScroll for more
NCT04847063Phase 1

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Recruiting
NCT07854964Not Applicable

A Prospective, Single-center, Phase II Study of Neoadjuvant Serplulimab Plus XELOX and Bevacizumab in Locally Advanced Rectal Cancer

Not Yet Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT07283939Not Applicable

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

Recruiting
NCT04408638Phase 3

A Phase III Study Evaluating Glofitamab in Combination With Gemcitabine + Oxaliplatin vs Rituximab in Combination With Gemcitabine + Oxaliplatin in Participants With Relapsed/Refractory Diffuse Large B-Cell Lymphoma

Active Not Recruiting
NCT06780111Phase 1

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Recruiting
NCT07490301Phase 2

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT05677490Phase 3

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Recruiting
NCT05203172Phase 4

The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials

Recruiting
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting
NCT02912559Phase 3

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Active Not Recruiting
NCT06788171Phase 2

PULSAR Combined With PD-1 Ab and Chemotherapy Plus Bev. for CRLM

Recruiting
NCT06078709Phase 2

Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma

Recruiting
NCT07469306Phase 2

Short-Course RT Plus CAPOX and Tislelizumab vs Long-Course CRT Plus Tislelizumab for Locally Advanced Rectal Cancer

Recruiting
NCT06997497Phase 3

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT03448835Phase 2

Neoadjuvant Capecitabine, Oxaliplatin, Docetaxel and Atezolizumab in Resectable Gastric and GE-junction Cancer (PANDA)

Active Not Recruiting
NCT07847229Phase 2

A Prospective, Biomarker-Stratified Phase 2 Study: β-Hydroxybutyrate as a Predictive Biomarker for Short-Course Radiotherapy Followed by Chemotherapy Plus PD-1 Inhibitor Versus Chemotherapy Alone in Locally Advanced Rectal Cancer

Not Yet Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,224