Success Metrics

Clinical Success Rate
78.7%

Based on 505 completed trials

Completion Rate
79%(505/642)
Active Trials
272(23%)
Results Posted
53%(270 trials)
Terminated
137(11%)

Phase Distribution

Ph early_phase_1
7
1%
Ph phase_1
286
24%
Ph phase_4
11
1%
Ph phase_2
665
55%
Ph phase_3
198
16%
Ph not_applicable
22
2%

Phase Distribution

293

Early Stage

665

Mid Stage

209

Late Stage

Phase Distribution1189 total trials
Early Phase 1First-in-human
7(0.6%)
Phase 1Safety & dosage
286(24.1%)
Phase 2Efficacy & side effects
665(55.9%)
Phase 3Large-scale testing
198(16.7%)
Phase 4Post-market surveillance
11(0.9%)
N/ANon-phased studies
22(1.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.7%

505 of 676 finished

Non-Completion Rate

25.3%

171 ended early

Currently Active

272

trials recruiting

Total Trials

1,203

all time

Status Distribution
Active(343)
Completed(505)
Terminated(171)
Other(184)

Detailed Status

Completed505
unknown182
Recruiting174
Terminated137
Active, not recruiting98
Not yet recruiting69

Development Timeline

Analytics

Development Status

Total Trials
1203
Active
272
Success Rate
78.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 17 (0.6%)
Phase 1286 (24.1%)
Phase 2665 (55.9%)
Phase 3198 (16.7%)
Phase 411 (0.9%)
N/A22 (1.9%)

Trials by Status

withdrawn343%
not_yet_recruiting696%
completed50542%
terminated13711%
enrolling_by_invitation20%
recruiting17414%
active_not_recruiting988%
suspended20%
unknown18215%

Recent Activity

Clinical Trials (1,203)

Showing 20 of 1,203 trialsScroll for more
NCT05564403Phase 2

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Active Not Recruiting
NCT06901531Phase 3

A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT05355701Phase 1

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT02912559Phase 3

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Active Not Recruiting
NCT06662786Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Recruiting
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting
NCT05067283Phase 1

A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001)

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT05139017Phase 2

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Recruiting
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting
NCT07737600Phase 1

A Study of MRG007 Combination Therapy for Advanced Colorectal Cancer

Not Yet Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT07733180Phase 2

A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC

Not Yet Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT07580339Phase 2

Combining DCSZ11 With Radiation and Chemotherapy as Neoadjuvant Treatment for pMMR Locally Advanced Rectal Cancer

Not Yet Recruiting
NCT07490301Phase 2

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT06835387Phase 2

Study of NALIRIFOX in Advanced Unresectable Small Bowel Tumors

Recruiting
NCT04847063Phase 1

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,203