Success Metrics

Clinical Success Rate
84.1%

Based on 369 completed trials

Completion Rate
84%(369/439)
Active Trials
123(18%)
Results Posted
37%(138 trials)
Terminated
70(10%)

Phase Distribution

Ph not_applicable
13
2%
Ph phase_2
323
46%
Ph phase_1
157
22%
Ph phase_3
195
28%
Ph early_phase_1
3
0%
Ph phase_4
2
0%

Phase Distribution

160

Early Stage

323

Mid Stage

197

Late Stage

Phase Distribution693 total trials
Early Phase 1First-in-human
3(0.4%)
Phase 1Safety & dosage
157(22.7%)
Phase 2Efficacy & side effects
323(46.6%)
Phase 3Large-scale testing
195(28.1%)
Phase 4Post-market surveillance
2(0.3%)
N/ANon-phased studies
13(1.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

79.7%

369 of 463 finished

Non-Completion Rate

20.3%

94 ended early

Currently Active

123

trials recruiting

Total Trials

698

all time

Status Distribution
Active(132)
Completed(369)
Terminated(94)
Other(103)

Detailed Status

Completed369
unknown100
Terminated70
Active, not recruiting64
Recruiting59
Withdrawn24

Development Timeline

Analytics

Development Status

Total Trials
698
Active
123
Success Rate
84.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (0.4%)
Phase 1157 (22.7%)
Phase 2323 (46.6%)
Phase 3195 (28.1%)
Phase 42 (0.3%)
N/A13 (1.9%)

Trials by Status

suspended30%
terminated7010%
withdrawn243%
active_not_recruiting649%
completed36953%
not_yet_recruiting91%
recruiting598%
unknown10014%

Recent Activity

Clinical Trials (698)

Showing 20 of 698 trialsScroll for more
NCT07409272Phase 3

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT04615013Phase 1

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Recruiting
NCT03161522Phase 2

Chemotherapy With or Without Radiation or Surgery in Treating Participants With Oligometastatic Esophageal or Gastric Cancer

Recruiting
NCT03776487Phase 2

Nivolumab, Ipilimumab and Chemoradiation in Treating Patients With Resectable Gastric Cancer

Active Not Recruiting
NCT04481204Phase 2

New and Emerging Therapies for the Treatment of Resectable, Borderline Resectable, or Locally Advanced Pancreatic Cancer, PIONEER-Panc Study

Active Not Recruiting
NCT06820463Phase 2

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT06654037Phase 1

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT02912559Phase 3

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Active Not Recruiting
NCT00217737Phase 3

Oxaliplatin, Leucovorin, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Active Not Recruiting
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting
NCT05379595Phase 1

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Recruiting
NCT03775265Phase 3

Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

Active Not Recruiting
NCT06696768Phase 1

Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

Recruiting
NCT06417476Phase 2

Short-course Radiotherapy or Long-course Chemoradiation Followed by mFOLFOXIRI Consolidation Chemotherapy for Organ Preservation in Low Rectal Cancer

Active Not Recruiting
NCT05564403Phase 2

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Active Not Recruiting
NCT02688712Phase 2

ExIST Study of LY2157299 (Galunisertib) in Rectal Cancer

Active Not Recruiting
NCT04929028Phase 2

Therapy Adapted for High Risk and Low Risk HIV-Associated Anal Cancer

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
698