Success Metrics

Clinical Success Rate
83.4%

Based on 371 completed trials

Completion Rate
83%(371/445)
Active Trials
125(18%)
Results Posted
38%(141 trials)
Terminated
74(10%)

Phase Distribution

Ph not_applicable
13
2%
Ph early_phase_1
3
0%
Ph phase_1
161
23%
Ph phase_3
198
28%
Ph phase_4
2
0%
Ph phase_2
325
46%

Phase Distribution

164

Early Stage

325

Mid Stage

200

Late Stage

Phase Distribution702 total trials
Early Phase 1First-in-human
3(0.4%)
Phase 1Safety & dosage
161(22.9%)
Phase 2Efficacy & side effects
325(46.3%)
Phase 3Large-scale testing
198(28.2%)
Phase 4Post-market surveillance
2(0.3%)
N/ANon-phased studies
13(1.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.9%

371 of 470 finished

Non-Completion Rate

21.1%

99 ended early

Currently Active

125

trials recruiting

Total Trials

707

all time

Status Distribution
Active(135)
Completed(371)
Terminated(99)
Other(102)

Detailed Status

Completed371
unknown99
Terminated74
Active, not recruiting65
Recruiting60
Withdrawn25

Development Timeline

Analytics

Development Status

Total Trials
707
Active
125
Success Rate
83.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (0.4%)
Phase 1161 (22.9%)
Phase 2325 (46.3%)
Phase 3198 (28.2%)
Phase 42 (0.3%)
N/A13 (1.9%)

Trials by Status

withdrawn254%
recruiting608%
suspended30%
active_not_recruiting659%
not_yet_recruiting101%
unknown9914%
terminated7410%
completed37152%

Recent Activity

Clinical Trials (707)

Showing 20 of 707 trialsScroll for more
NCT06269978Phase 1

Intraperitoneal Oxaliplatin and Fluorouracil for the Treatment of Patients With Peritoneal Metastases From Colorectal Cancer

Active Not Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT07744126Phase 2

A Study to Assess Adverse Events, Change in Disease Activity and Optimal Dose of Intravenous (IV) Telisotuzumab Adizutecan With IV Pembrolizumab for First-Line Treatment of Adult Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Not Yet Recruiting
NCT07566156Phase 3

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

Recruiting
NCT07748611Phase 2

SMAD4 Tailored Neoadjuvant Therapy for the Treatment of Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma, SMART-PANC Trial

Not Yet Recruiting
NCT07283939Not Applicable

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

Recruiting
NCT05677490Phase 3

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Recruiting
NCT04999761Phase 1

AB122 Platform Study

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT05863195Phase 3

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Recruiting
NCT02912559Phase 3

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Active Not Recruiting
NCT07490301Phase 2

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT06820463Phase 2

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Recruiting
NCT00588770Phase 3

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Active Not Recruiting
NCT03775265Phase 3

Chemoradiotherapy With or Without Atezolizumab in Treating Patients With Localized Muscle Invasive Bladder Cancer

Active Not Recruiting
NCT05564403Phase 2

Study of Chemotherapy, With or Without Binimetinib in Advanced Biliary Tract Cancers in 2nd Line Setting (A ComboMATCH Treatment Trial)

Active Not Recruiting
NCT06654037Phase 1

Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer

Recruiting
NCT05568095Phase 3

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body

Active Not Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
707