Success Metrics

Clinical Success Rate
83.9%

Based on 370 completed trials

Completion Rate
84%(370/441)
Active Trials
125(18%)
Results Posted
37%(138 trials)
Terminated
71(10%)

Phase Distribution

Ph phase_3
198
28%
Ph phase_2
323
46%
Ph phase_4
2
0%
Ph early_phase_1
3
0%
Ph phase_1
160
23%
Ph not_applicable
13
2%

Phase Distribution

163

Early Stage

323

Mid Stage

200

Late Stage

Phase Distribution699 total trials
Early Phase 1First-in-human
3(0.4%)
Phase 1Safety & dosage
160(22.9%)
Phase 2Efficacy & side effects
323(46.2%)
Phase 3Large-scale testing
198(28.3%)
Phase 4Post-market surveillance
2(0.3%)
N/ANon-phased studies
13(1.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

79.4%

370 of 466 finished

Non-Completion Rate

20.6%

96 ended early

Currently Active

125

trials recruiting

Total Trials

704

all time

Status Distribution
Active(135)
Completed(370)
Terminated(96)
Other(103)

Detailed Status

Completed370
unknown100
Terminated71
Active, not recruiting63
Recruiting62
Withdrawn25

Development Timeline

Analytics

Development Status

Total Trials
704
Active
125
Success Rate
83.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (0.4%)
Phase 1160 (22.9%)
Phase 2323 (46.2%)
Phase 3198 (28.3%)
Phase 42 (0.3%)
N/A13 (1.9%)

Trials by Status

withdrawn254%
recruiting629%
active_not_recruiting639%
not_yet_recruiting101%
suspended30%
unknown10014%
completed37053%
terminated7110%

Recent Activity

Clinical Trials (704)

Showing 20 of 704 trialsScroll for more
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT06820463Phase 2

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Recruiting
NCT01154920Phase 2

Paclitaxel, Carboplatin and Cetuximab (PCC) With Cetuximab, Docetaxel, Cisplatin and Fluorouracil (C-TPF) in Previously Untreated Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma

Active Not Recruiting
NCT07490301Phase 2

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT05365581Phase 1

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

Recruiting
NCT07214298Phase 1

Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT07566156Phase 3

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

Recruiting
NCT07579195Phase 1

Consolidative Therapy After EV + Pembrolizumab in Muscle Invasive Bladder Cancer, REINFORCE Trial

Not Yet Recruiting
NCT05379595Phase 1

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

Recruiting
NCT05355701Phase 1

A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.

Recruiting
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting
NCT07619313Phase 1

AB801 in Combination With Chemotherapy and Immunotherapy for the Treatment of Patients With Borderline Resectable, Locally Advanced or Metastatic Cholangiocarcinoma or Pancreatic Cancer

Not Yet Recruiting
NCT05253651Phase 3

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

Recruiting
NCT06696768Phase 1

Clinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal Cancer

Recruiting
NCT00492999Phase 2

Hepatic Arterial Infusion With Floxuridine and Dexamethasone Combined With Combination Chemotherapy in Treating Patients With Colorectal Cancer That Has Spread to the Liver

Active Not Recruiting
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting
NCT03899155Phase 2

Pan Tumor Rollover Study

Recruiting
NCT07456852Phase 1

Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy

Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
704