Success Metrics

Clinical Success Rate
83.6%

Based on 376 completed trials

Completion Rate
84%(376/450)
Active Trials
128(18%)
Results Posted
38%(141 trials)
Terminated
74(10%)

Phase Distribution

Ph phase_3
199
28%
Ph not_applicable
13
2%
Ph phase_4
2
0%
Ph early_phase_1
3
0%
Ph phase_1
165
23%
Ph phase_2
327
46%

Phase Distribution

168

Early Stage

327

Mid Stage

201

Late Stage

Phase Distribution709 total trials
Early Phase 1First-in-human
3(0.4%)
Phase 1Safety & dosage
165(23.3%)
Phase 2Efficacy & side effects
327(46.1%)
Phase 3Large-scale testing
199(28.1%)
Phase 4Post-market surveillance
2(0.3%)
N/ANon-phased studies
13(1.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

79.2%

376 of 475 finished

Non-Completion Rate

20.8%

99 ended early

Currently Active

128

trials recruiting

Total Trials

714

all time

Status Distribution
Active(138)
Completed(376)
Terminated(99)
Other(101)

Detailed Status

Completed376
unknown98
Terminated74
Recruiting64
Active, not recruiting64
Withdrawn25

Development Timeline

Analytics

Development Status

Total Trials
714
Active
128
Success Rate
83.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (0.4%)
Phase 1165 (23.3%)
Phase 2327 (46.1%)
Phase 3199 (28.1%)
Phase 42 (0.3%)
N/A13 (1.8%)

Trials by Status

completed37653%
not_yet_recruiting101%
suspended30%
recruiting649%
terminated7410%
unknown9814%
withdrawn254%
active_not_recruiting649%

Recent Activity

Clinical Trials (714)

Showing 20 of 714 trialsScroll for more
NCT03340896Phase 3

Trial of Laryngeal Preservation Comparing Induced CT Followed by RT vs CT Concomitant to RT

Active Not Recruiting
NCT06770582Phase 2

Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial

Recruiting
NCT07283939Not Applicable

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

Recruiting
NCT05564377Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Recruiting
NCT05677490Phase 3

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Recruiting
NCT07490301Phase 2

A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
NCT02912559Phase 3

Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair

Active Not Recruiting
NCT06078709Phase 2

Preoperative Hypofractionated Radiotherapy With FOLFOX for Esophageal or Gastroesophageal Junction Adenocarcinoma

Recruiting
NCT00588770Phase 3

Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Active Not Recruiting
NCT02997228Phase 3

Testing the Addition of Atezolizumab to Combination Chemotherapy or Atezolizumab Alone for Metastatic Colon or Rectal Cancer, the COMMIT Study

Active Not Recruiting
NCT05382559Phase 1

A Study of ASP3082 in Adults With Advanced Solid Tumors

Recruiting
NCT07566156Phase 3

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

Recruiting
NCT07848568Phase 1

Testing Safe Doses of Anti-Cancer Medicines, 5-Flurouracil (5-FU) and Tretinoin (ATRA), Added to the Usual Cancer Treatment of Ependymoma

Not Yet Recruiting
NCT07744126Phase 2

A Study to Assess Adverse Events, Change in Disease Activity and Optimal Dose of Intravenous (IV) Telisotuzumab Adizutecan With IV Pembrolizumab for First-Line Treatment of Adult Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Recruiting
NCT05329766Phase 2

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies

Active Not Recruiting
NCT05891171Phase 1

Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers

Active Not Recruiting
NCT06820463Phase 2

A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

Recruiting
NCT07844187Phase 1

TQB2922 Injection Given Under the Skin With Chemotherapy as Initial Treatment for Colorectal Cancer That Has Spread

Not Yet Recruiting
NCT07271355Phase 3

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

Recruiting
NCT07277270Phase 1

A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
714