Success Metrics

Clinical Success Rate
77.3%

Based on 377 completed trials

Completion Rate
77%(377/488)
Active Trials
129(17%)
Results Posted
64%(242 trials)
Terminated
111(15%)

Phase Distribution

Ph early_phase_1
6
1%
Ph phase_2
370
50%
Ph phase_1
248
34%
Ph phase_3
81
11%
Ph not_applicable
16
2%
Ph phase_4
3
0%

Phase Distribution

254

Early Stage

370

Mid Stage

84

Late Stage

Phase Distribution724 total trials
Early Phase 1First-in-human
6(0.8%)
Phase 1Safety & dosage
248(34.3%)
Phase 2Efficacy & side effects
370(51.1%)
Phase 3Large-scale testing
81(11.2%)
Phase 4Post-market surveillance
3(0.4%)
N/ANon-phased studies
16(2.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.9%

377 of 517 finished

Non-Completion Rate

27.1%

140 ended early

Currently Active

129

trials recruiting

Total Trials

739

all time

Status Distribution
Active(145)
Completed(377)
Terminated(140)
Other(77)

Detailed Status

Completed377
Terminated111
Recruiting79
unknown73
Active, not recruiting50
Withdrawn29

Development Timeline

Analytics

Development Status

Total Trials
739
Active
129
Success Rate
77.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 16 (0.8%)
Phase 1248 (34.3%)
Phase 2370 (51.1%)
Phase 381 (11.2%)
Phase 43 (0.4%)
N/A16 (2.2%)

Trials by Status

active_not_recruiting507%
recruiting7911%
not_yet_recruiting152%
enrolling_by_invitation10%
terminated11115%
suspended41%
unknown7310%
completed37751%
withdrawn294%

Recent Activity

Clinical Trials (739)

Showing 20 of 739 trialsScroll for more
NCT07247110Phase 1

A Clinical Study of MK-4716 in People With Certain Solid Tumors (MK-4716-001)

Recruiting
NCT07672483Phase 1

IL-12 Genetically Engineered Myeloid Cells in Participants With Relapsed, Refractory Solid Tumors

Not Yet Recruiting
NCT07644559Phase 2

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

Recruiting
NCT07209111Phase 2

A Clinical Study of Calderasib (MK-1084) in People With Advanced Solid Tumors (MK-1084-014)

Recruiting
NCT00265850Phase 3

Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer

Completed
NCT06997497Phase 3

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

Recruiting
NCT07286149Phase 1

A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F)

Recruiting
NCT07659795Phase 2

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

Recruiting
NCT07042295Phase 2

Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System

Recruiting
NCT06589804Phase 3

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

Recruiting
NCT07746141Phase 1

A First-in-Human Study Investigating BG-85738 Alone or in Combination With Other Antitumor Agents in Patients With Advanced or Metastatic Solid Tumors With Rat Sarcoma Virus (RAS) Mutations

Not Yet Recruiting
NCT05863195Phase 3

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

Recruiting
NCT06908031Phase 2

SCRT+mFOLFOX6+PD-1 Antibody and Targeted Therapy for High-Risk pMMR/MSS Rectal Cancer

Completed
NCT07702032Phase 3

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer

Recruiting
NCT06358430Phase 1

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Active Not Recruiting
NCT03258554Phase 2

Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin

Completed
NCT06102902Phase 1

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

Suspended
NCT06750094Phase 3

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Recruiting
NCT06662786Phase 3

A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer

Recruiting
NCT05217446Phase 2

A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer

Active Not Recruiting

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
739