NCT00051207

Brief Summary

This 6-month study, with a 3-month follow up period, will compare the effectiveness of new and traditional psychotherapies for depression with panic or anxiety symptoms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
36

participants targeted

Target at P25-P50 for phase_1 depression

Timeline
Completed

Started Nov 2002

Typical duration for phase_1 depression

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2002

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 7, 2003

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 8, 2003

Completed
2.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2005

Completed
Last Updated

June 25, 2013

Status Verified

December 1, 2007

First QC Date

January 7, 2003

Last Update Submit

June 21, 2013

Conditions

Keywords

Mood DisordersPsychotherapyComorbidity

Interventions

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • DSM-IV diagnosis of major depression with co-existing panic or anxiety symptoms.

You may not qualify if:

  • History of manic episode(s). Patients who have had hypomanic episodes in the past will be accepted into the study, provided they meet other admission criteria and are not presenting in a current hypomanic or mixed episode.
  • History of schizophrenia or schizoaffective disorder.
  • Organic affective syndrome.
  • Unspecified functional psychosis.
  • Anorexia nervosa or bulimia nervosa. Patients meeting criteria for an eating disorder not otherwise specified will not be excluded.
  • Chronic drug or alcohol abuse/dependence within the past 2 years. Patients with abuse related to episodes will not be excluded.
  • DSM-IV criteria for borderline or antisocial personality disorder. Patients who meet criteria for other Axis II disorders will not be excluded.
  • Inpatient treatment due to suicide risk or psychotic symptoms.
  • Index episode secondary to the effect of medically prescribed drugs.
  • Significant or untreated medical illness, including cardiovascular disorder, renal or liver disease, epilepsy, untreated hypertension, or unstabilized endocrine disease.
  • Medical illness that would interfere with the best treatment strategy for the potential participant.
  • Current treatment with an antidepressant. Patients on a stable dose of anxiolytics for at least 3 months prior to study participation who are able to maintain this dosage throughout the study will not be excluded.
  • Pregnant and breast-feeding women will be accepted into the study, but will not be prescribed adjunctive medications.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Western Psychiatric Institute and Clinic - Depression and Manic Depression Program

Pittsburgh, Pennsylvania, 15213, United States

Location

MeSH Terms

Conditions

DepressionAnxiety DisordersPanic DisorderMood Disorders

Interventions

Interpersonal Psychotherapyadenylate isopentenyltransferase

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorMental Disorders

Intervention Hierarchy (Ancestors)

PsychotherapyBehavioral Disciplines and Activities

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

January 7, 2003

First Posted

January 8, 2003

Study Start

November 1, 2002

Study Completion

August 1, 2005

Last Updated

June 25, 2013

Record last verified: 2007-12

Locations