Comparison of Two Psychotherapy Treatments for Depressed Women With a History of Sexual Abuse
Interpersonal Psychotherapy for Depressed Women With Sexual Abuse Histories
2 other identifiers
interventional
70
1 country
1
Brief Summary
This study will compare the effectiveness of individual versus interpersonal psychotherapy in treating depressed women with a history of sexual abuse.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for phase_1 depression
Started May 2003
Longer than P75 for phase_1 depression
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2003
CompletedFirst Submitted
Initial submission to the registry
November 21, 2005
CompletedFirst Posted
Study publicly available on registry
November 22, 2005
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2007
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2007
CompletedJanuary 3, 2014
December 1, 2013
4.3 years
November 21, 2005
December 31, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Hamilton Rating Scale for Depression
Measured at pre-treatment and Weeks 10, 24, and 36
Beck Depression Inventory
Measured at pre-treatment and Weeks 10, 24, and 36
Structured Clinical Interview for DSM-IV Diagnoses
Measured at pre-treatment and Weeks 10, 24, and 36
Secondary Outcomes (3)
Social Adjustment Scale
Measured at pre-treatment and Weeks 10, 24, and 36
Medical Outcomes Survey
Measured at pre-treatment and Weeks 10, 24, and 36
Post Traumatic Stress Disorder (PTSD) Symptom Scale
Measured at pre-treatment and Weeks 10, 24, and 36
Study Arms (2)
Interpersonal Psychotherapy (IPT)
EXPERIMENTALInterpersonal Psychotherapy
Individual Psychotherapy
ACTIVE COMPARATORIndividual Psychotherapy
Interventions
Interpersonal Psychotherapy
Eligibility Criteria
You may qualify if:
- Meets DSM-IV criteria for unipolar major depressive disorder
- History of childhood sexual abuse before the age of 18
- Seeking outpatient psychotherapy treatment in a community mental health center
You may not qualify if:
- Meets DSM-IV criteria for major depression with psychotic features, bipolar disorder, schizophrenia, or mental retardation
- Active alcohol or substance abuse within 3 months of study entry date
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Rochester Medical Center
Rochester, New York, 14642, United States
Related Publications (7)
Talbot NL, Conwell Y, O'Hara MW, Stuart S, Ward EA, Gamble SA, Watts A, Tu X. Interpersonal psychotherapy for depressed women with sexual abuse histories: a pilot study in a community mental health center. J Nerv Ment Dis. 2005 Dec;193(12):847-50. doi: 10.1097/01.nmd.0000188987.07734.22.
PMID: 16319710RESULTTalbot NL, Chaudron LH, Ward EA, Duberstein PR, Conwell Y, O'Hara MW, Tu X, Lu N, He H, Stuart S. A randomized effectiveness trial of interpersonal psychotherapy for depressed women with sexual abuse histories. Psychiatr Serv. 2011 Apr;62(4):374-80. doi: 10.1176/ps.62.4.pss6204_0374.
PMID: 21459988RESULTSmith PN, Gamble SA, Cort NA, Ward EA, He H, Talbot NL. Attachment and alliance in the treatment of depressed, sexually abused women. Depress Anxiety. 2012 Feb;29(2):123-30. doi: 10.1002/da.20913. Epub 2011 Nov 7.
PMID: 22065593RESULTSmith PN, Gamble SA, Cort NA, Ward EA, Conwell Y, Talbot NL. The relationships of attachment style and social maladjustment to death ideation in depressed women with a history of childhood sexual abuse. J Clin Psychol. 2012 Jan;68(1):78-87. doi: 10.1002/jclp.20852. Epub 2011 Nov 28.
PMID: 22125120RESULTCankaya B, Talbot NL, Ward EA, Duberstein PR. Parental sexual abuse and suicidal behaviour among women with major depressive disorder. Can J Psychiatry. 2012 Jan;57(1):45-51. doi: 10.1177/070674371205700108.
PMID: 22296967RESULTYou S, Talbot NL, He H, Conner KR. Emotions and suicidal ideation among depressed women with childhood sexual abuse histories. Suicide Life Threat Behav. 2012 Jun;42(3):244-54. doi: 10.1111/j.1943-278X.2012.00086.x. Epub 2012 Mar 12.
PMID: 22409700RESULTCort NA, Gamble SA, Smith PN, Chaudron LH, Lu N, He H, Talbot NL. Predictors of treatment outcomes among depressed women with childhood sexual abuse histories. Depress Anxiety. 2012 Jun;29(6):479-86. doi: 10.1002/da.21942. Epub 2012 May 8.
PMID: 22570264RESULT
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Nancy L. Talbot, PhD
University of Rochester
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
November 21, 2005
First Posted
November 22, 2005
Study Start
May 1, 2003
Primary Completion
August 1, 2007
Study Completion
August 1, 2007
Last Updated
January 3, 2014
Record last verified: 2013-12