NCT00031200

Brief Summary

To investigate the composition and nature of weight loss and weight maintenance during the Look AHEAD trial. Also, to model changes in resting energy expenditure and changes in cardiac structure and function associated with weight loss.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Sep 2001

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2001

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

February 27, 2002

Completed
1 day until next milestone

First Posted

Study publicly available on registry

February 28, 2002

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2007

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2007

Completed
Last Updated

July 29, 2016

Status Verified

January 1, 2008

Enrollment Period

5.4 years

First QC Date

February 27, 2002

Last Update Submit

July 28, 2016

Conditions

Cardiovascular DiseasesAtherosclerosisObesityDiabetes Mellitus, Non-insulin DependentHeart DiseasesMyocardial InfarctionDiabetes Mellitus

Eligibility Criteria

Age45 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
An estimated 140 obese, diabetic men and women, ages 45 or older. There will be 70 women (50%) and 20% minorities

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (2)

  • Gallagher D, Song MY. Evaluation of body composition: practical guidelines. Prim Care. 2003 Jun;30(2):249-65. doi: 10.1016/s0095-4543(03)00030-7.

    PMID: 14567146BACKGROUND

  • He Q, Horlick M, Thornton J, Wang J, Pierson RN Jr, Heshka S, Gallagher D. Sex-specific fat distribution is not linear across pubertal groups in a multiethnic study. Obes Res. 2004 Apr;12(4):725-33. doi: 10.1038/oby.2004.85.

    PMID: 15090643BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesAtherosclerosisObesityDiabetes Mellitus, Type 2Heart DiseasesMyocardial InfarctionDiabetes Mellitus

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular DiseasesOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsGlucose Metabolism DisordersMetabolic DiseasesEndocrine System DiseasesMyocardial IschemiaInfarctionIschemiaPathologic ProcessesNecrosis

Study Officials

  • Dympna Gallagher

    St. Luke's-Roosevelt Hospital Center

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

February 27, 2002

First Posted

February 28, 2002

Study Start

September 1, 2001

Primary Completion

February 1, 2007

Study Completion

February 1, 2007

Last Updated

July 29, 2016

Record last verified: 2008-01