NCT00005547

Brief Summary

To investigate the role of chronic infection as a risk factor for vascular disease in a study of Native Americans. The primary focus is on the two most common agents Chlamydia pneumoniae and cytomegalovirus with a secondary emphasis on Helicobacter pylori.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Timeline
Completed

Started Apr 1999

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 1999

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2000

Completed
1 day until next milestone

First Posted

Study publicly available on registry

May 26, 2000

Completed
3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2003

Completed
Last Updated

February 18, 2016

Status Verified

January 1, 2005

First QC Date

May 25, 2000

Last Update Submit

February 17, 2016

Conditions

Cardiovascular DiseasesCoronary DiseaseCerebrovascular AccidentHeart DiseasesMyocardial InfarctionInfectionChlamydia InfectionsCytomegalovirus InfectionsHelicobacter InfectionsAtherosclerosis

Eligibility Criteria

AgeUp to 100 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
No eligibility criteria

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

Related Publications (1)

  • Best LG, Davidson M, North KE, MacCluer JW, Zhang Y, Lee ET, Howard BV, DeCroo S, Ferrell RE. Prospective analysis of mannose-binding lectin genotypes and coronary artery disease in American Indians: the Strong Heart Study. Circulation. 2004 Feb 3;109(4):471-5. doi: 10.1161/01.CIR.0000109757.95461.10. Epub 2004 Jan 19.

    PMID: 14732744BACKGROUND

MeSH Terms

Conditions

Cardiovascular DiseasesCoronary DiseaseStrokeHeart DiseasesMyocardial InfarctionInfectionsChlamydia InfectionsCytomegalovirus InfectionsHelicobacter InfectionsAtherosclerosis

Condition Hierarchy (Ancestors)

Myocardial IschemiaVascular DiseasesCerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosisChlamydiaceae InfectionsGram-Negative Bacterial InfectionsBacterial InfectionsBacterial Infections and MycosesSexually Transmitted Diseases, BacterialSexually Transmitted DiseasesCommunicable DiseasesGenital DiseasesUrogenital DiseasesHerpesviridae InfectionsDNA Virus InfectionsVirus DiseasesArteriosclerosisArterial Occlusive Diseases

Study Officials

  • Michael Davidson

    Medlantic Research Institute

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

May 25, 2000

First Posted

May 26, 2000

Study Start

April 1, 1999

Study Completion

June 1, 2003

Last Updated

February 18, 2016

Record last verified: 2005-01