Technical Evaluation of Cardiovascular Magnetic Resonance Imaging and Spectroscopy
2 other identifiers
observational
400
1 country
1
Brief Summary
Magnetic resonance imaging (MRI) and spectroscopy are diagnostic tools that create high quality images of the human body without the use of X-ray (radiation). MRI uses different levels of magnetic fields to create images of the body and organs. Occasionally, researchers will give patients undergoing a MRI an injection of a contrast substance. The contrast substance works by brightening areas of the magnetic resonance image. In this study researchers plan to use magnetic resonance imaging with contrast substances and exercise on normal volunteers in order to evaluate different aspects of its performance. Information gathered from this study may be used to develop more specific research studies involving MRI....
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 1999
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 22, 1999
CompletedFirst Submitted
Initial submission to the registry
November 3, 1999
CompletedFirst Posted
Study publicly available on registry
November 4, 1999
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 3, 2009
CompletedStudy Completion
Last participant's last visit for all outcomes
August 3, 2009
CompletedJuly 2, 2017
August 3, 2009
10.5 years
November 3, 1999
June 30, 2017
Conditions
Keywords
Eligibility Criteria
You may qualify if:
- Any normal volunteer above the age 18 who is capable of giving informed consent will be included.
You may not qualify if:
- A subject will be excluded if he/she has a contradiction to MR scanning.
- Brain aneurysm clip
- Implanted neural stimulator
- Implanted cardiac pacemaker implanted defibrillator
- Cochlear implant
- Ocular foreign body (e.g. metal shavings)
- Insulin pump
- Pregnant women (when uncertain, subjects will undergo urine or blood testing).
- Kidney
- Paralyzed hemidiaphragm
- Morbid obesity
- Claustrophobia
- Any condition in the PI's judgement which present unncessary risk
- Lactating women
- Subjects with hemoglobinopathies
- +4 more criteria
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Suburban Hospital
Bethesda, Maryland, 20814, United States
Related Publications (3)
Frank JA, Mattay VS, Duyn J, Sobering G, Barrios FA, Zigun J, Sexton R, Kwok P, Woo J, Moonen C, et al. Measurement of relative cerebral blood volume changes with visual stimulation by 'double-dose' gadopentetate-dimeglumine-enhanced dynamic magnetic resonance imaging. Invest Radiol. 1994 Jun;29 Suppl 2:S157-60. doi: 10.1097/00004424-199406001-00052. No abstract available.
PMID: 7928216BACKGROUNDMattay VS, Weinberger DR, Barrios FA, Sobering GS, Kotrla KJ, van Gelderen P, Duyn JH, Sexton RH, Moonen CT, Frank JA. Brain mapping with functional MR imaging: comparison of gradient-echo--based exogenous and endogenous contrast techniques. Radiology. 1995 Mar;194(3):687-91. doi: 10.1148/radiology.194.3.7862963.
PMID: 7862963BACKGROUNDNiendorf HP, Dinger JC, Haustein J, Cornelius I, Alhassan A, Clauss W. Tolerance data of Gd-DTPA: a review. Eur J Radiol. 1991 Jul-Aug;13(1):15-20. doi: 10.1016/0720-048x(91)90049-2.
PMID: 1889423BACKGROUND
MeSH Terms
Conditions
Study Design
- Study Type
- observational
- Sponsor Type
- NIH
Study Record Dates
First Submitted
November 3, 1999
First Posted
November 4, 1999
Study Start
February 22, 1999
Primary Completion
August 3, 2009
Study Completion
August 3, 2009
Last Updated
July 2, 2017
Record last verified: 2009-08-03