NCT00001192

Brief Summary

This study will allow researchers to use various types of tests to evaluate cognitive and sensory functions. These tests, referred to as "batteries" will evaluate attention, executive functions, general intellectual functioning, language, memory, motor functions, orientation, personality, selected sensory and perceptual functions, vigilance (alertness), and visual-spatial functions. Children and adult patient will receive different test batteries. The goals of this research study are to;

  1. 1.Create descriptions based on the performance of each patient on the test batteries. Then use this information to relate patient behavior to their neurophysiological, neuroradiological, and biochemical descriptions.
  2. 2.Define subgroups of patients based on their neurobehavior in order to decrease the variability of psychiatric diagnoses, treatments, and prognoses.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 1983

Longer than P75 for all trials

Geographic Reach
3 countries

7 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 18, 1983

Completed
16.1 years until next milestone

First Submitted

Initial submission to the registry

November 3, 1999

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 4, 1999

Completed
7.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 20, 2006

Completed
Last Updated

July 2, 2017

Status Verified

December 20, 2006

First QC Date

November 3, 1999

Last Update Submit

June 30, 2017

Conditions

Keywords

Executive FunctionsLanguageAttentionVisual-Spatial AbilityMemoryMotor BehaviorIntelligencePersonalityVisual and Auditory FunctioningHand and Eye DominanceNormal VolunteerNeuropsychiatric Disorders

Eligibility Criteria

AgeUp to 95 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Patients.
  • Normal volunteers.

You may not qualify if:

  • Subjects over 95 years of age.
  • Subjects with a history of alcohol or drug abuse, psychopathology, or central nervous system pathology, other than that which defines group membership, may be excluded.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

Childrens National Medical Center

Washington D.C., District of Columbia, United States

Location

National Institutes of Health Clinical Center, 9000 Rockville Pike

Bethesda, Maryland, 20892, United States

Location

Henry Ford Health Systems

Detroit, Michigan, 48202, United States

Location

Mt. Sinai Medical Center

New York, New York, 10029-0574, United States

Location

Columbia University

New York, New York, 10032-3784, United States

Location

Genethon

Every Cedex, France

Location

Mosco Research Institute of Psychiatry

Moscow, Russia

Location

Related Publications (1)

  • Johnstone EC, Owens DG, Bydder GM, Colter N, Crow TJ, Frith CD. The spectrum of structural brain changes in schizophrenia: age of onset as a predictor of cognitive and clinical impairments and their cerebral correlates. Psychol Med. 1989 Feb;19(1):91-103. doi: 10.1017/s0033291700011053.

    PMID: 2727213BACKGROUND

MeSH Terms

Conditions

Anxiety DisordersCraniocerebral TraumaMood DisordersSchizophreniaSeizuresLanguageMotor Activity

Condition Hierarchy (Ancestors)

Mental DisordersTrauma, Nervous SystemNervous System DiseasesWounds and InjuriesSchizophrenia Spectrum and Other Psychotic DisordersNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsCommunicationBehavior

Study Design

Study Type
observational
Sponsor Type
NIH

Study Record Dates

First Submitted

November 3, 1999

First Posted

November 4, 1999

Study Start

October 18, 1983

Study Completion

December 20, 2006

Last Updated

July 2, 2017

Record last verified: 2006-12-20

Locations