Self-Management Therapy for Youth With Schizophrenia

NCT00000387 | Completed Phase 3

• 2 other identifiers: R01MH056580DSIR CT-S
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to test the effectiveness of a family-centered, community-based, self-management intervention (Self-Management Therapy) for adolescents with schizophrenia. The study will test the intervention's effectiveness in improving the adolescents' behavior, thinking, mood, and use of substances such as drugs and alcohol. The study also will look at the effects of the patient on the family. The intervention involves training in recognizing symptoms of schizophrenia and in stress management, problem-solving, and social skills. Parents and siblings are included to gain knowledge and skills to support the adolescents. The Self-Management Therapy intervention is administered in small multiple-family groups in 12 sessions over 7-1/2 months. The effects of the intervention on the patient and his/her family are assessed prior to treatment, after 6 sessions, after 12 sessions, and in a follow-up visit 6 months after completion of sessions. A child may be eligible for this study if he/she: Is 15 to 19 years old and has been diagnosed with schizophrenia.

Conditions

Schizophrenia

Keywords

Adolescence; Family; Female; Human; Male; Schizophrenia; Self Care; Community Health Services

Outcome Measures

Primary Outcomes (1)

• Increase in CAFAS level of functioning for all adolescents.

  Over the course of 14 months

Secondary Outcomes (1)

• Increase in family functioning for families in the treatment group according to the designated family respondent.

  Over the course of 14 months

Study Arms (2)

A,1,III

EXPERIMENTAL

Behavioral intervention - Self management therapy

Behavioral: Self-management therapy

A,2,III

ACTIVE COMPARATOR

Regular treatment

Behavioral: Self-management therapy

Interventions

Self-management therapy BEHAVIORAL

Behavioral

A,1,III; A,2,III

Eligibility Criteria

• Age: 15 Years - 19 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Patients must have:
• Schizophrenia as diagnosed according to DSM-IV criteria when screened by a mental health professional using the K-SADS and the DISA.

Sponsors & Collaborators

• National Institute of Mental Health (NIMH): lead

Study Sites (1)

University of Washington

Seattle, Washington, 98195, United States

Location

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Officials

• Karen G. Schepp, PhD

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: NIH

Study Record Dates

• First Submitted: November 2, 1999
• First Posted: November 3, 1999
• Study Start: April 1, 1998
• Primary Completion: January 1, 2005
• Study Completion: January 1, 2005
• Last Updated: December 28, 2007

Record last verified: 2007-12

Locations

US (1)