Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Moderate Risk

Score: 50/100

Failure Rate

12.1%

4 terminated/withdrawn out of 33 trials

Success Rate

77.8%

-8.7% vs industry average

Late-Stage Pipeline

21%

7 trials in Phase 3/4

Results Transparency

43%

6 of 14 completed trials have results

Key Signals

8 recruiting6 with results

Enrollment Performance

Analytics

Phase 1
13(39.4%)
Phase 2
12(36.4%)
Phase 3
7(21.2%)
N/A
1(3.0%)
33Total
Phase 1(13)
Phase 2(12)
Phase 3(7)
N/A(1)

Activity Timeline

Global Presence

Loading network data...

Clinical Trials (33)

Showing 20 of 33 trials
NCT07218146Phase 3Recruiting

A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)

Role: lead

NCT06885281Phase 1Recruiting

A Study of ZL-1310 in Participants With Selected Solid Tumors

Role: lead

NCT07374848Phase 1Recruiting

Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

Role: lead

NCT07211776Phase 3Recruiting

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

Role: lead

NCT07235384Phase 1Recruiting

A Phase 1/1b Study to Evaluate Safety, Tolerability and Pharmacokinetics of ZL-1503 in Healthy Volunteers and Participants With Moderate to Severe Atopic Dermatitis

Role: lead

NCT05810948Phase 2Completed

A Study to Assess Effectiveness and Safety of Efgartigimod in Chinese Patients With Lupus Nephritis (ZL-1103-013)

Role: collaborator

NCT05919823Phase 3Completed

A Study to Assess the Efficacy and Safety of KarXT in Acutely Psychotic Hospitalized Chinese Adult Subjects With DSM-5 Schizophrenia

Role: collaborator

NCT06140836Phase 3Active Not Recruiting

A Study of Repotrectinib Versus Crizotinib in Participants With Locally Advanced or Metastatic Tyrosine Kinase Inhibitor (TKI)-naïve ROS1-positive Non-Small Cell Lung Cancer (NSCLC) (TRIDENT-3)

Role: collaborator

NCT06179069Phase 1Recruiting

A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

Role: lead

NCT03093116Phase 1Recruiting

A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

Role: collaborator

NCT04082364Phase 2Completed

Combination Margetuximab, Retifanlimab, Tebotelimab, and Chemotherapy Phase 2/3 Trial in HER2+ Gastric/GEJ Cancer

Role: collaborator

NCT04282980Phase 2Completed

A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST)

Role: lead

NCT04633122Phase 2Completed

A Study to Assess DCC-2618 and Sunitinib in Patients With Advanced GIST After Treatment With Imatinib

Role: lead

NCT04281576Not ApplicableCompleted

Effect of Tumor Treating Fields (TTFields, 150 KHz) Concomitant with Chemotherapy As First Line Treatment of Unresectable Gastroesophageal Junction or Gastric Adenocarcinoma

Role: collaborator

NCT04212221Phase 1Terminated

MGD013 Monotherapy and Combination With Brivanib Dose Escalation and Expansion Study in Advanced Liver Cancer Patients

Role: lead

NCT03694522Phase 2Completed

A Study of Bemarituzumab (FPA144) Combined With Modified FOLFOX6 (mFOLFOX6) in Gastric/Gastroesophageal Junction Cancer

Role: collaborator

NCT04653038Phase 1Terminated

A Study to Evaluate the Safety and Efficacy of MGD013 in Patients With Melanoma

Role: lead

NCT04716686Phase 2Recruiting

Niraparib Monotherapy as Maintain and Recurrent Treatment of Endometrial Serous Carcinoma

Role: collaborator

NCT05866354Phase 1Completed

To Evaluate Pharmacokinetics of Tisotumab Vedotin in Chinese Subjects With Metastatic or Recurrent Solid Malignancies

Role: lead

NCT04262804Phase 2Unknown

A Study to Evaluate the Efficacy and Safety of Margetuximab Plus Chemotherapy in the Treatment of Chinese Patients With HER2+ MBC

Role: lead