Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

8.8%

35 terminated/withdrawn out of 398 trials

Success Rate

89.0%

+2.4% vs industry average

Late-Stage Pipeline

28%

111 trials in Phase 3/4

Results Transparency

53%

151 of 283 completed trials have results

Key Signals

26 recruiting151 with results27 terminated8 withdrawn

Enrollment Performance

Analytics

Phase 1
142(42.9%)
Phase 2
63(19.0%)
Phase 3
60(18.1%)
Phase 4
51(15.4%)
N/A
14(4.2%)
Early Phase 1
1(0.3%)
331Total
Phase 1(142)
Phase 2(63)
Phase 3(60)
Phase 4(51)
+2 more

Activity Timeline

Global Presence

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Clinical Trials (398)

Showing 20 of 398 trials
NCT06646562Phase 4Active Not Recruiting

Long Acting Cabotegravir Plus Rilpivirine in People Living With HIV-1 Aged ≥ 60 Years for 24 Months.

Role: collaborator

NCT06694805Phase 3Active Not Recruiting

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

Role: lead

NCT05514509Phase 4Completed

A Study Evaluating Implementation Strategies for the Delivery of APRETUDE for Black cis-and Transgender Women in United States EHE Territories

Role: lead

NCT07053384Phase 1Active Not Recruiting

A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV

Role: lead

NCT07650916Phase 3Recruiting

A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed

Role: lead

NCT05549726Phase 4Completed

SEARCH CAB LA Dynamic Choice HIV Prevention Study Extension

Role: collaborator

NCT04553081Phase 4Completed

2DR Versus 3DR in a Prospective Randomized Controlled Switch Trial

Role: collaborator

NCT07616739Phase 4Recruiting

Dolutegravir/Lamivudine in Treatment-Naïve Pregnant Women

Role: collaborator

NCT03449706Recruiting

Accurate Staging of Immuno-virological Dynamics During Acute HIV Infection

Role: collaborator

NCT03635788Phase 3Completed

The LATITUDE Study: Long-Acting Therapy to Improve Treatment SUccess in Daily LifE

Role: collaborator

NCT07822477Phase 1Not Yet Recruiting

A Study to Investigate Safety, Tolerability and Pharmacokinetics of VH5356136 in Adult Participants Without HIV

Role: lead

NCT07818915Phase 1Not Yet Recruiting

A Study to Investigate Pharmacokinetics (PK), Safety, and Tolerability of VH4367310 in Healthy Adult Participants

Role: lead

NCT07816250Phase 2Not Yet Recruiting

A Phase 2b Study Evaluating VH4011499 Capsid Inhibitor Long-Acting Injectable Plus Cabotegravir in Treatment Naïve Adults (CINERGY)

Role: lead

NCT06497465Phase 3Recruiting

Dolutegravir/Lamivudine Dual Therapy for ART-naïve People With HIV and TB Receiving Rifampin-based TB Treatment

Role: collaborator

NCT04880785Phase 2Completed

Lamivudine/Dolutegravir in Virologically Suppressed Subjects With Expected or Confirmed Resistance to Lamivudine

Role: collaborator

NCT04518228Terminated

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

Role: collaborator

NCT02362503Phase 3Active Not Recruiting

Attachment Inhibitor Comparison in Heavily Treatment Experienced Patients

Role: lead

NCT07595042Phase 2Not Yet Recruiting

A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)

Role: collaborator

NCT07393659Phase 3Recruiting

A Continued Access Study for Participants Transitioning From ViiV Healthcare-sponsored or ViiV Healthcare-collaborative Parent Studies for HIV Treatment

Role: lead

NCT06310551Phase 1Recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

Role: lead