Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 25/100

Failure Rate

8.7%

34 terminated/withdrawn out of 393 trials

Success Rate

89.2%

+2.7% vs industry average

Late-Stage Pipeline

28%

109 trials in Phase 3/4

Results Transparency

52%

146 of 281 completed trials have results

Key Signals

25 recruiting146 with results26 terminated8 withdrawn

Enrollment Performance

Analytics

Phase 1
140(42.9%)
Phase 2
62(19.0%)
Phase 3
58(17.8%)
Phase 4
51(15.6%)
N/A
14(4.3%)
Early Phase 1
1(0.3%)
326Total
Phase 1(140)
Phase 2(62)
Phase 3(58)
Phase 4(51)
+2 more

Activity Timeline

Global Presence

Loading network data...

Clinical Trials (393)

Showing 20 of 393 trials
NCT07370649Recruiting

Long-Acting Cabotegravir and Rilpivirine in People Living With HIV-1 Subtype A6: A Real-World Retrospective Study

Role: collaborator

NCT07636928Phase 1Not Yet Recruiting

Mass Balance and Absolute Oral Bioavailability of [14C]VH4524184

Role: lead

NCT07616739Phase 4Not Yet Recruiting

Dolutegravir/Lamivudine in Treatment-Naïve Pregnant Women

Role: collaborator

NCT04484337Phase 1Completed

Study to Evaluate Pharmacokinetic (PK), Safety and Tolerability of Cabotegravir (CAB) 400 Milligrams Per Milliliter (mg/mL) Formulation in Healthy Adult Participants

Role: lead

NCT06694805Phase 3Recruiting

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

Role: lead

NCT05917509Phase 3Completed

A Study to Evaluate the Efficacy, Safety, Participant Choice and Preference of an Oral Once-daily Regimen or a Long-acting Injectable Regimen Every Two Months for Treatment of Human Immunodeficiency Virus (HIV-1) in Adults Who Have Not Previously Taken Antiretroviral Therapy

Role: lead

NCT05406583Phase 1Completed

A Study of the Safety, Tolerability, and Pharmacokinetics of Dolutegravir in Neonates Exposed to HIV-1

Role: collaborator

NCT07275606Phase 1Recruiting

A Study to Investigate Cabotegravir for Neonates Exposed to HIV-1

Role: lead

NCT07595042Phase 2Not Yet Recruiting

A Trial of Stratified Patient-Centered Treatment Regimens for Active TB (SPECTRA-TB)

Role: collaborator

NCT05911360Phase 3Completed

A Study to Evaluate Efficacy, Safety and Tolerability in Antiretroviral Therapy (ART)-Experienced Participants of at Least 50 Years of Age Living With Human Immunodeficiency Virus (HIV) With Virologic Suppression Who Switch to DTG/3TC FDC From BIC/FTC/TAF

Role: lead

NCT07202546Phase 2Recruiting

A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

Role: lead

NCT06310551Phase 1Recruiting

First Time in Human Study of Long Acting VH4524184 Formulations

Role: lead

NCT06451341Active Not Recruiting

IMplementation of CAB+RPV LA for People With HIV in Non-Metropolitan Areas

Role: collaborator

NCT06444620Phase 3Active Not Recruiting

B/F/TAF to DTG/3TC Switch Study

Role: collaborator

NCT04133012Not ApplicableCompleted

Cartography of Virologic Reservoir Related to Antiretroviral Concentrations in HIV-1 Chronic Patients Treated by a First Line Treatment Containing Dolutegravir and Associated Nucleoside / Nucleotide Reverse Transcriptase Inhibitors Backbone

Role: collaborator

NCT07525544Phase 1Not Yet Recruiting

A Study to Investigate the Safety and PK of VH4770359 in Healthy Participants

Role: lead

NCT01420523Phase 2Terminated

Evaluation of Raltegravir Plus Maraviroc Therapy in Controlled HIV Patients Presenting With Lipohypertrophy

Role: collaborator

NCT07053384Phase 1Active Not Recruiting

A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV

Role: lead

NCT07199335Phase 4Recruiting

Long-acting Cabotegravir Injectable Pre-exposure Prophylaxis for People Who Inject Drugs

Role: collaborator

NCT02720094Phase 2Completed

Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men

Role: collaborator