Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

High Risk

Score: 80/100

Failure Rate

27.6%

8 terminated/withdrawn out of 29 trials

Success Rate

69.2%

-17.3% vs industry average

Late-Stage Pipeline

21%

6 trials in Phase 3/4

Results Transparency

11%

2 of 18 completed trials have results

Key Signals

2 with results7 terminated

Enrollment Performance

Analytics

Phase 2
13(48.1%)
Phase 1
7(25.9%)
Phase 3
5(18.5%)
N/A
1(3.7%)
Phase 4
1(3.7%)
27Total
Phase 2(13)
Phase 1(7)
Phase 3(5)
N/A(1)
+1 more

Activity Timeline

Global Presence

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Clinical Trials (29)

Showing 20 of 29 trials
NCT00457678Phase 2Withdrawn

Second Line Therapy to Treat Age-related Macular Degeneration (AMD) for Patients Not Responding Well to Lucentis Therapy by Itself

Role: collaborator

NCT02575430Completed

Natural History Study in Inherited Retinal Disease Subjects Caused by Mutations in RPE65 or LRAT

Role: lead

NCT00242580Phase 3Completed

A Safety and Efficacy Study Comparing the Combination Treatments of Verteporfin Therapy Plus One of Two Different Doses of Intravitreal Triamcinolone Acetonide and the Verteporfin Therapy Plus Intravitreal Pegaptanib

Role: collaborator

NCT01999764Phase 2Completed

Evaluation of the Effects of Oral QLT091001 in Adults With Impaired Dark Adaptation

Role: lead

NCT01543906Phase 1Completed

Oral QLT091001 in Retinitis Pigmentosa (RP) Subjects With an Autosomal Dominant Mutation in Retinal Pigment Epithelial 65 Protein (RPE65)

Role: lead

NCT01521793Phase 1Completed

Repeated Treatments of QLT091001 in Subjects With Leber Congenital Amaurosis or Retinitis Pigmentosa (Extension of Study RET IRD 01)

Role: lead

NCT01037036Phase 2Completed

A Study of the L-PPDS With Adjunctive Xalatan® Eye Drops in Subjects With OH or OAG

Role: collaborator

NCT00007969Phase 1Completed

Photodynamic Therapy in Treating Patients With Stage III or Stage IV Melanoma

Role: lead

NCT00821002Phase 2Completed

A Phase 2 Study of Punctal Placement of the Latanoprost Punctal Plug Delivery System (L-PPDS)

Role: collaborator

NCT01014052Phase 1Completed

Safety/Proof of Concept Study of Oral QLT091001 in Subjects With Leber Congenital Amaurosis (LCA) or Retinitis Pigmentosa (RP) Due to Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) Mutations

Role: lead

NCT00077012Phase 1Completed

Dose Escalation Study With QLT0074 for Benign Prostatic Hyperplasia

Role: lead

NCT00042315Phase 3Terminated

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of Tariquidar + Vinorelbine as First-Line Therapy in Non-Small Cell Lung Cancer (NSCLC)

Role: lead

NCT00048633Phase 2Completed

Phase II Study to Evaluate Tariquidar (XR9576), a Selective MDR-1 Inhibitor, in Chemotherapy Resistant Advanced Breast Cancer

Role: lead

NCT00042302Phase 3Terminated

A Double-Blind, Randomized, Placebo-Controlled, Multicenter, Phase III Study of Tariquidar + Paclitaxel/Carboplatin as First-Line Therapy in Non-Small Cell Lung Cancer (NSCLC)

Role: lead

NCT00376701Phase 2Completed

Combination Therapy for Age-Related Macular Degeneration.

Role: collaborator

NCT00492284Phase 2Completed

Reduced Fluence Visudyne-Anti-VEGF-Dexamethasone In Combination for AMD Lesions (RADICAL)

Role: lead

NCT00381602Phase 2Terminated

A Phase II, Randomized, Cross-Over, Vehicle-Controlled, Double-Blind, Multicenter Study of the Safety, Pharmacodynamics, and Preliminary Efficacy of GHRP-1/AG in Subjects With ESRD on Hemodialysis

Role: lead

NCT00049959Phase 3Terminated

Two Studies to Determine if Verteporfin PDT is Effective & Safe in Treating Multiple Basal Cell Carcinoma of the Skin.

Role: lead

NCT01253954Unknown

A Multicenter Observational Study of Invasive Candida Infections Among ICU Patients in China

Role: collaborator

NCT00390208Phase 2Completed

Triple Therapy - PDT Plus IVD and Intravitreal Ranibizumab Versus Lucentis Monotherapy to Treat Age-Related Macular Degeneration

Role: collaborator