Key Highlights

Risk & Performance

Pipeline Risk Assessment

Pipeline Risk Assessment

Based on historical performance

Low Risk

Score: 5/100

Failure Rate

0.0%

0 terminated/withdrawn out of 24 trials

Success Rate

100.0%

+13.5% vs industry average

Late-Stage Pipeline

38%

9 trials in Phase 3/4

Results Transparency

96%

22 of 23 completed trials have results

Key Signals

22 with results

Enrollment Performance

Analytics

Phase 2
11(45.8%)
Phase 3
6(25.0%)
Phase 1
4(16.7%)
Phase 4
3(12.5%)
24Total
Phase 2(11)
Phase 3(6)
Phase 1(4)
Phase 4(3)

Activity Timeline

Global Presence

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Clinical Trials (24)

Showing 20 of 24 trials
NCT02319837Phase 3Active Not Recruiting

Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK)

Role: collaborator

NCT02003924Phase 3Completed

Safety and Efficacy Study of Enzalutamide in Patients With Nonmetastatic Castration-Resistant Prostate Cancer

Role: collaborator

NCT02677896Phase 3Completed

A Study of Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus ADT in Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC)

Role: collaborator

NCT02288247Phase 3Completed

A Study to Assess the Benefit of Treatment Beyond Progression With Enzalutamide in Men Who Are Starting Treatment With Docetaxel After Worsening of Their Prostate Cancer When Taking Enzalutamide Alone

Role: collaborator

NCT02091960Phase 2Completed

A Study to Assess the Efficacy and Safety of Enzalutamide With Trastuzumab in Patients With Human Epidermal Growth Factor Receptor 2 Positive (HER2+), Androgen Receptor Positive (AR+) Metastatic or Locally Advanced Breast Cancer

Role: collaborator

NCT01889238Phase 2Completed

Safety and Efficacy Study of Enzalutamide in Patients With Advanced, Androgen Receptor-Positive, Triple Negative Breast Cancer

Role: collaborator

NCT01650194Phase 2Completed

A Study to Determine Safety and Tolerability of Enzalutamide (MDV3100) in Combination With Abiraterone Acetate in Bone Metastatic Castration-Resistant Prostate Cancer Patients

Role: collaborator

NCT02116582Phase 4Completed

A Study to Evaluate Enzalutamide After Abiraterone in Metastatic Castration-Resistant Prostate Cancer

Role: collaborator

NCT02799745Phase 2Completed

A Randomized Study of Enzalutamide in Patients With Localized Prostate Cancer Undergoing Active Surveillance

Role: collaborator

NCT01288911Phase 2Completed

A Study of Enzalutamide Versus Bicalutamide in Castrate Men With Metastatic Prostate Cancer

Role: collaborator

NCT01534052Phase 2Completed

A Study to Assess the Safety of Continued Administration of MDV3100 in Subjects With Prostate Cancer Who Showed Benefit From Prior Exposure to MDV3100

Role: collaborator

NCT01977651Phase 4Completed

A Study to Evaluate the Potential Increased Risk of Seizures Among Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients Treated With Enzalutamide

Role: collaborator

NCT01284920Phase 1Completed

A Study of MDV3100 to Evaluate Safety, Tolerability, Pharmacokinetics and Efficacy of in Prostate Cancer Patients

Role: collaborator

NCT02124668Phase 2Completed

A Study to Monitor the Safety of Enzalutamide in Patients With Progressive Castration-Resistant Prostate Cancer Previously Treated With Docetaxel-Based Chemotherapy

Role: collaborator

NCT01995513Phase 4Completed

Safety Study of Continued Enzalutamide Treatment In Prostate Cancer Patients

Role: collaborator

NCT02384382Phase 2Completed

A Positron Emission Tomography/Computed Tomography (PET/CT) Bone Imaging Study in Patients Receiving Enzalutamide for Castration-Resistant Prostate Cancer (CRPC)

Role: collaborator

NCT01212991Phase 3Completed

A Safety and Efficacy Study of Oral MDV3100 in Chemotherapy-Naive Patients With Progressive Metastatic Prostate Cancer

Role: collaborator

NCT00510718Phase 1Completed

A Phase 1 Study of MDV3100 in Patients With Castration-Resistant (Hormone-Refractory) Prostate Cancer

Role: collaborator

NCT01597193Phase 1Completed

Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer

Role: collaborator

NCT01565928Phase 1Completed

Safety and Tolerability Study of MDV3100 in Combination With Docetaxel in Men With Advanced Prostate Cancer

Role: collaborator