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Published trial results

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Drug Portfolio

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Trial Phases

Phase 14
Phase 28
Phase 33

Trial Status

Completed12
Terminated2
Other1

Role Distribution

Other Roles15

Activity Timeline

Clinical Trials (15)

NCT04598542Phase 1Completed
Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers
Drug-Drug Interaction
StudydirectorStart date: 2020-10-13
NCT03706521Phase 2Terminated
MRI Study to Evaluate the Safety and Efficacy of SM04690 for Knee Osteoarthritis
Knee Osteoarthritis
StudydirectorStart date: 2019-03-11

Showing 10 of 15 trials

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CO
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Clinical Trials (15)

Showing 15 of 15 trials

NCT04598542Phase 1StudyDirector

Drug-Drug Interaction Study of Lorecivivint and Triamcinolone Acetonide in Healthy Volunteers

Drug-Drug Interaction
Completed
NCT04385303Phase 3StudyDirector

Patient-Reported Outcomes in Evaluating Lorecivivint (SM04690) for Moderate to Severe Knee Osteoarthritis (STRIDES-1)

Knee Osteoarthritis
Completed
NCT03928184Phase 3StudyDirector

Patient-Reported and Radiographic Outcomes in Evaluating Lorecivivint (SM04690) for the Treatment of Knee Osteoarthritis

Knee Osteoarthritis
Completed
NCT03706521Phase 2StudyDirector

MRI Study to Evaluate the Safety and Efficacy of SM04690 for Knee Osteoarthritis

Knee Osteoarthritis
Terminated
NCT03727022Phase 2StudyDirector

Safety and Bone Health Study of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis

Knee Osteoarthritis
Completed
NCT03742518Phase 2/3StudyDirector

A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia

Androgenetic Alopecia
Completed
NCT03502434Phase 1StudyDirector

A Repeat Insult Patch Test (RIPT) Study Evaluating the Sensitization Potential of Topical SM04755 Solution in Healthy Volunteers

Tendinopathy
Completed
NCT03246399Phase 1StudyDirector

A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease

Degenerative Disc Disease
Terminated
NCT03122860Phase 2StudyDirector

A Study Evaluating the Safety and Efficacy of SM04690 for the Treatment of Moderately to Severely Symptomatic Knee Osteoarthritis

Knee Osteoarthritis
Completed
NCT03229291Phase 1StudyDirector

A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of SM04755 Following Topical Administration to Healthy Subjects

Tendinopathy
Completed
NCT02951026StudyDirector

An Observational Study Evaluating the Safety, Tolerability, and Efficacy of Treatment of SM04690 or Placebo Previously Injected in the Target Knee Joint of Subjects With Moderately to Severely Symptomatic Osteoarthritis

Osteoarthritis
Completed
NCT02536833Phase 2StudyDirector

A Study Evaluating the Safety, Tolerability, and Efficacy of SM04690 Injected in the Target Knee Joint of Moderately to Severely Symptomatic Osteoarthritis Subjects

Osteoarthritis
Completed
NCT02275351Phase 2StudyDirector

A Study of the Safety, Tolerability, and Efficacy of Topical SM04554 Solution in Male Subjects With Androgenetic Alopecia (AGA)

Androgenetic Alopecia
Completed
NCT02503137Phase 2StudyDirector

A Study of SM04554 Applied Topically to the Scalp of Male Subjects With Androgenetic Alopecia Analyzed by Biopsy of the Scalp Prior To and Post Dosing

Androgenetic Alopecia
Completed
NCT03591926Phase 2StudyDirector

A Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of SM04646 Inhalation Solution in Subjects With Idiopathic Pulmonary Fibrosis (IPF)

Idiopathic Pulmonary Fibrosis
Withdrawn

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