Degenerative Disc Disease
253
32
44
109
Key Insights
Highlights
Success Rate
78% trial completion
Published Results
34 trials with published results (13%)
Research Maturity
109 completed trials (43% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 72/100
12.3%
31 terminated out of 253 trials
77.9%
-8.7% vs benchmark
9%
22 trials in Phase 3/4
31%
34 of 109 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 109 completed trials
Clinical Trials (253)
Biologic Injection For Adults With Lumbar Disc Herniation
"Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nulcectomy" (LOPAIN2)
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
A Phase 3 Study of AGA111 in Patients With Degenerative Disc Disease Undergoing Lumbar Interbody Fusion
Clinical Outcome Measure at Stryker Spine
Efficacy and Safety of Rexlemestrocel-L Combined With HA* in Participants With Moderate to Severe Chronic Low Back Pain
ASCEND: A Clinical Trial to Evaluate the Safety and Effectiveness of VIA Disc NP, a Supplement for Degenerated Intervertebral Discs
OssDsign® Spine Registry Study ("Propel")
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Study to Determine the Safety and Tolerability of TG-C in Subjects With Back Pain Due to Degenerative Disc Disease
LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF)
Carbofix Pedicle Screw System: Evaluation of the Clinical and Radiographic Outcomes of the Use of a Carbon Fiber Device Compared to Titanium Devices in Patients Undergoing Spinal Arthrodesis for Degenerative Spinal Diseases
Long-term Assessment of BDyn Dynamic Stabilization Device in Patients With Lumbar Degenerative Disc Disease
Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease
Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
The European Robotic Spinal Instrumentation (EUROSPIN) Study
Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical
Anterior Cervical Disectomy And Fusion Using The Tritanium® C Anterior Cervical Cage For One Or Two-Levels