Degenerative Disc Disease
251
30
41
109
Key Insights
Highlights
Success Rate
78% trial completion
Published Results
34 trials with published results (14%)
Research Maturity
109 completed trials (43% of total)
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 72/100
12.0%
30 terminated out of 251 trials
78.4%
-8.1% vs benchmark
9%
22 trials in Phase 3/4
31%
34 of 109 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 109 completed trials
Clinical Trials (251)
OssDsign® Spine Registry Study ("Propel")
Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease
Biologic Injection For Adults With Lumbar Disc Herniation
The European Robotic Spinal Instrumentation (EUROSPIN) Study
Post-Market Clinical Follow-Up Study on the Safety and Performance of Ennovate® Cervical
Anterior Cervical Disectomy And Fusion Using The Tritanium® C Anterior Cervical Cage For One Or Two-Levels
Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion
"Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nulcectomy" (LOPAIN2)
Adaptix RCT Evaluating Adaptix™ Versus PEEK Cages
MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion
Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease
Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery
Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury
Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain
Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty
Erector Spinae Plane Block vs Local Infiltration Following Fusion Surgery
Study of the ReGelTec HYDRAFIL System
A Clinical Study to Evaluate Safety and Performance of PEEK-OPTIMA™ HA Enhanced.
A Phase 3 Study of AGA111 in Patients With Degenerative Disc Disease Undergoing Lumbar Interbody Fusion