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Published trial results

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Drug Portfolio

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Trial Phases

Phase 112
Phase 22
Phase 39

Trial Status

Completed18
Terminated4
Other1

Role Distribution

Other Roles23

Activity Timeline

Clinical Trials (20)

NCT03315143Phase 3Terminated
Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk
Chronic Kidney DiseasesHeart FailureType 2 Diabetes Mellitus
StudydirectorStart date: 2017-12-19

Showing 10 of 20 trials

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Collaboration Network

1 collaborators·0 connections
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CO
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Clinical Trials (23)

Showing 20 of 23 trials

NCT03521934Phase 3StudyDirector

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Heart FailureType 2 Diabetes Mellitus
Terminated
NCT03386344Phase 3StudyDirector

Efficacy and Bone Safety of Sotagliflozin 400 and 200 mg Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control

Type 2 Diabetes Mellitus
Terminated
NCT03315143Phase 3StudyDirector

Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk

Chronic Kidney DiseasesHeart FailureType 2 Diabetes Mellitus
Terminated
NCT03292653Phase 2StudyDirector

Safety, Tolerability and Pharmacodynamic Activity of Sotagliflozin in Hemodynamically Stable Participants With Worsening Heart Failure

Cardiac Failure Aggravated
Terminated
NCT03332771Phase 3StudyDirector

Efficacy and Safety of Sotagliflozin Versus Glimepiride and Placebo in Participants With Type 2 Diabetes Mellitus That Are Taking Metformin Monotherapy

Type 2 Diabetes Mellitus
Completed
NCT03423446Phase 1StudyDirector

Study to Evaluate the Pharmacokinetics of Telotristat Ethyl in Subjects With Severe Hepatic Impairment

Hepatic Impairment
Completed
NCT03302845Phase 1StudyDirector

A Phase 1 Study to Evaluate the Effects of Omeprazole and Famotidine on the Absorption of Telotristat Ethyl in Healthy Subjects

Drug-drug Interaction
Completed
NCT03285594Phase 3StudyDirector

Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking Insulin Alone or With Other Oral Antidiabetic Agents

Type 2 Diabetes Mellitus
Completed
NCT03242018Phase 3StudyDirector

A Study to Evaluate Safety and Effects of Sotagliflozin 400 and 200 mg on Glucose Control in Participants With Type 2 Diabetes, Severe Impairment of Kidney Function and Inadequate Blood Sugar Control

Chronic Kidney Disease Stage 4Type 2 Diabetes Mellitus
Completed
NCT03242252Phase 3StudyDirector

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control

Chronic Kidney Disease Stage 3Type 2 Diabetes Mellitus
Completed
NCT02926937Phase 3StudyDirector

Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus Not Currently Treated With Antidiabetic Therapy

Type 2 Diabetes Mellitus
Completed
NCT02926950Phase 3StudyDirector

Efficacy and Safety of Sotagliflozin Versus Placebo in Patients With Type 2 Diabetes Mellitus on Background of Metformin

Type 2 Diabetes Mellitus
Completed
NCT02647918Phase 1StudyDirector

Study to Evaluate Sotagliflozin in Subjects With Varying Degrees of Renal Function

HealthyRenal Impairment
Completed
NCT02459899Phase 2StudyDirector

Dose-ranging Study in Patients With Type 1 Diabetes Mellitus

Type 1 Diabetes Mellitus
Completed
NCT02147808Phase 1StudyDirector

A Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Midazolam in Healthy Subjects

Drug Interactions
Completed
NCT02155205Phase 1StudyDirector

A Thorough QT Study of Telotristat Etiprate

QT Interval
Completed
NCT02157558Phase 1StudyDirector

An Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Fexofenadine in Healthy Subjects

Drug Interactions
Completed
NCT02157584Phase 1StudyDirector

An Open-Label Food Effect Study of Telotristat Etiprate

Healthy
Completed
NCT02195635Phase 1StudyDirector

Phase 1, Open-label, Drug-drug Interaction Study With Octreotide Acetate Injection and Telotristat Etiprate in Healthy Subjects

Drug Interactions
Completed
NCT02300350Phase 1StudyDirector

DDI Study With Multiple-dose LX4211 and Single Dose Digoxin

Healthy
Completed