Success Metrics

Clinical Success Rate
77.8%

Based on 14 completed trials

Completion Rate
78%(14/18)
Active Trials
8(29%)
Results Posted
100%(14 trials)
Terminated
4(14%)

Phase Distribution

Ph phase_3
13
46%
Ph early_phase_1
1
4%
Ph phase_2
6
21%
Ph phase_1
4
14%
Ph phase_4
3
11%

Phase Distribution

5

Early Stage

6

Mid Stage

16

Late Stage

Phase Distribution27 total trials
Early Phase 1First-in-human
1(3.7%)
Phase 1Safety & dosage
4(14.8%)
Phase 2Efficacy & side effects
6(22.2%)
Phase 3Large-scale testing
13(48.1%)
Phase 4Post-market surveillance
3(11.1%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

77.8%

14 of 18 finished

Non-Completion Rate

22.2%

4 ended early

Currently Active

8

trials recruiting

Total Trials

28

all time

Status Distribution
Active(9)
Completed(14)
Terminated(4)
Other(1)

Detailed Status

Completed14
Recruiting7
Terminated4
unknown1
Active, not recruiting1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
28
Active
8
Success Rate
77.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (3.7%)
Phase 14 (14.8%)
Phase 26 (22.2%)
Phase 313 (48.1%)
Phase 43 (11.1%)

Trials by Status

unknown14%
completed1450%
active_not_recruiting14%
not_yet_recruiting14%
recruiting725%
terminated414%

Recent Activity

Clinical Trials (28)

Showing 20 of 28 trialsScroll for more
NCT06618976Phase 4

Antithrombotic Activities of Sotagliflozin vs. Empagliflozin

Completed
NCT07547878Phase 4

Simultaneous Starting of the 4 Guideline Directed CKD Therapies (RAPID-CKD)

Active Not Recruiting
NCT06217302Phase 3

Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease

Recruiting
NCT06481891Phase 3

A Study to Evaluate the Efficacy and Safety of Sotagliflozin in Symptomatic Obstructive and Non-obstructive Hypertrophic Cardiomyopathy

Recruiting
NCT06433050Early Phase 1

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy

Recruiting
NCT06510894

Diagnostic Utility of SGLT1/2 Inhibition to Facilitate Myocardial Glucose Suppression

Recruiting
NCT06435156Phase 2

Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes

Recruiting
NCT05562063Phase 4

Sotagliflozin in Heart Failure With Preserved Ejection Fraction (HFpEF) Patients

Completed
NCT06147232Phase 2

Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxia

Not Yet Recruiting
NCT06082063Phase 3

Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes

Recruiting
NCT05696366Phase 1

Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 Diabetes

Recruiting
NCT03521934Phase 3

Effect of Sotagliflozin on Cardiovascular Events in Participants With Type 2 Diabetes Post Worsening Heart Failure (SOLOIST-WHF Trial)

Terminated
NCT03315143Phase 3

Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk

Terminated
NCT03242018Phase 3

A Study to Evaluate Safety and Effects of Sotagliflozin 400 and 200 mg on Glucose Control in Participants With Type 2 Diabetes, Severe Impairment of Kidney Function and Inadequate Blood Sugar Control

Completed
NCT03242252Phase 3

Safety and Efficacy Study of Sotagliflozin on Glucose Control in Participants With Type 2 Diabetes, Moderate Impairment of Kidney Function, and Inadequate Blood Sugar Control

Completed
NCT03386344Phase 3

Efficacy and Bone Safety of Sotagliflozin 400 and 200 mg Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control

Terminated
NCT03351478Phase 3

Efficacy and Safety of Sotagliflozin Versus Placebo and Empagliflozin in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking a DPP4 Inhibitor Alone or With Metformin

Completed
NCT03285594Phase 3

Efficacy and Safety of Sotagliflozin Versus Placebo in Participants With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control While Taking Insulin Alone or With Other Oral Antidiabetic Agents

Completed
NCT03292653Phase 2

Safety, Tolerability and Pharmacodynamic Activity of Sotagliflozin in Hemodynamically Stable Participants With Worsening Heart Failure

Terminated
NCT02459899Phase 2

Dose-ranging Study in Patients With Type 1 Diabetes Mellitus

Completed

Drug Details

Intervention Type
DRUG
Total Trials
28