Success Metrics

Clinical Success Rate
89.1%

Based on 834 completed trials

Completion Rate
89%(834/936)
Active Trials
106(8%)
Results Posted
43%(359 trials)
Terminated
102(8%)

Phase Distribution

Ph early_phase_1
38
3%
Ph phase_1
213
16%
Ph not_applicable
148
11%
Ph phase_2
298
23%
Ph phase_3
276
21%
Ph phase_4
305
23%

Phase Distribution

251

Early Stage

298

Mid Stage

581

Late Stage

Phase Distribution1278 total trials
Early Phase 1First-in-human
38(3.0%)
Phase 1Safety & dosage
213(16.7%)
Phase 2Efficacy & side effects
298(23.3%)
Phase 3Large-scale testing
276(21.6%)
Phase 4Post-market surveillance
305(23.9%)
N/ANon-phased studies
148(11.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

84.9%

834 of 982 finished

Non-Completion Rate

15.1%

148 ended early

Currently Active

106

trials recruiting

Total Trials

1,311

all time

Status Distribution
Active(148)
Completed(834)
Terminated(148)
Other(181)

Detailed Status

Completed834
unknown180
Terminated102
Recruiting80
Withdrawn46
Not yet recruiting36

Development Timeline

Analytics

Development Status

Total Trials
1311
Active
106
Success Rate
89.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 138 (3.0%)
Phase 1213 (16.7%)
Phase 2298 (23.3%)
Phase 3276 (21.6%)
Phase 4305 (23.9%)
N/A148 (11.6%)

Trials by Status

unknown18014%
withdrawn464%
active_not_recruiting262%
completed83464%
enrolling_by_invitation60%
recruiting806%
not_yet_recruiting363%
suspended10%
terminated1028%

Recent Activity

Clinical Trials (1,311)

Showing 20 of 1,311 trialsScroll for more
NCT06377696Phase 2

Remote Cognitive Assessment and Wearable Device While Assessing the Impact of Metformin in Patients With History of Cranial Radiation Therapy

Active Not Recruiting
NCT06924658Phase 2

Metformin in Safety and Efficacy in Gouty Patients

Recruiting
NCT06813924Phase 1

A Research Study of the Effect of Etavopivat on Other Drugs in Healthy Participants

Completed
NCT07585396Phase 2

Inositol in Letrozol Resistant PCOS Women

Completed
NCT05183204Phase 2

Paxalisib With a High Fat, Low Carb Diet and Metformin for Glioblastoma

Completed
NCT02365597Phase 2

An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer

Active Not Recruiting
NCT07815808Phase 3

Cardioprotective Effect of Empagliflozin in Breast Cancer Patients

Not Yet Recruiting
NCT02040376Phase 3

Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma

Completed
NCT02969798Not Applicable

Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

Recruiting
NCT07811011Phase 2

Efficacy of Vildagliptin Versus Metformin in Patients With Polycystic Ovary Syndrome

Not Yet Recruiting
NCT00814372Phase 2

Evaluate Safety and Effectiveness of MBX-102 in Type 2 Diabetes Patients With Poor Glycemic Control on Metformin

Terminated
NCT06995339Phase 2

Comparative Clinical and Biochemical Study Evaluating the Effectiveness of Metformin Versus Febuxostat on Gouty Obese Non-Diabetic Patients

Completed
NCT03617458Phase 2

Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension

Completed
NCT03603912Phase 4

Targeting Risk Interventions and Metformin for Atrial Fibrillation (TRIM-AF)

Active Not Recruiting
NCT07811856Phase 4

Effects of Metformin and Theory-Based Education in Women With Polycystic Ovary Syndrome

Completed
NCT03424005Phase 1

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

Recruiting
NCT07810998Phase 2

Efficacy of Dapagliflozin Versus Metformin in Polycystic Ovary Syndrome

Not Yet Recruiting
NCT03006172Phase 1

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

Active Not Recruiting
NCT05580250Phase 1

A Study of LY3526318 in Healthy Male Japanese Participants

Withdrawn
NCT07520110Phase 3

Metformin to Attenuate Progressive Respiratory Decline in Idiopathic Pulmonary Fibrosis

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,311