Success Metrics

Clinical Success Rate
47.4%

Based on 9 completed trials

Completion Rate
47%(9/19)
Active Trials
14(33%)
Results Posted
156%(14 trials)
Terminated
10(23%)

Phase Distribution

Ph not_applicable
1
2%
Ph phase_3
1
2%
Ph phase_1
7
16%
Ph phase_2
33
77%

Phase Distribution

7

Early Stage

33

Mid Stage

1

Late Stage

Phase Distribution42 total trials
Phase 1Safety & dosage
7(16.7%)
Phase 2Efficacy & side effects
33(78.6%)
Phase 3Large-scale testing
1(2.4%)
N/ANon-phased studies
1(2.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

47.4%

9 of 19 finished

Non-Completion Rate

52.6%

10 ended early

Currently Active

14

trials recruiting

Total Trials

43

all time

Status Distribution
Active(15)
Completed(9)
Terminated(10)
Other(9)

Detailed Status

Recruiting13
Terminated10
Completed9
unknown9
Not yet recruiting1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
43
Active
14
Success Rate
47.4%
Most Advanced
Phase 3

Trials by Phase

Phase 17 (16.7%)
Phase 233 (78.6%)
Phase 31 (2.4%)
N/A1 (2.4%)

Trials by Status

completed921%
not_yet_recruiting12%
terminated1023%
recruiting1330%
unknown921%
active_not_recruiting12%

Recent Activity

Clinical Trials (43)

Showing 20 of 43 trialsScroll for more
NCT07434843Phase 2

PH 2 Pemigatinib in SDH-deficient GIST

Recruiting
NCT06728410Phase 2

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

Recruiting
NCT06906562Phase 2

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Recruiting
NCT06302621Phase 1

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

Recruiting
NCT06439485Phase 1

Phase I/II Trial of Pemigatinib in Combination With Atezolizumab and Bevacizumab for Treatment of Advanced Cholangiocarcinoma With FGFR2 Fusion

Recruiting
NCT05267106Phase 2

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Glioblastoma or Other Primary Central Nervous System Tumors Harboring Activating FGFR1-3 Alterations

Terminated
NCT04659616Phase 1

Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia

Recruiting
NCT04463771Phase 2

Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy.

Active Not Recruiting
NCT06300528Phase 2

Pemigatinib in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphomas

Recruiting
NCT03498521Phase 2

A Phase II Randomized Study Comparing the Efficacy and Safety of Targeted Therapy or Cancer Immunotherapy Versus Platinum-Based Chemotherapy in Patients With Cancer of Unknown Primary Site

Completed
NCT03011372Phase 2

A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement - (FIGHT-203)

Completed
NCT03822117Phase 2

Efficacy and Safety of Pemigatinib in Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR Mutations or Translocations (FIGHT-207)

Terminated
NCT04003610Phase 2

Pemigatinib + Pembrolizumab vs Pemigatinib Alone vs Standard of Care for Urothelial Carcinoma (FIGHT-205)

Terminated
NCT03914794Phase 2

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

Completed
NCT06389799Phase 2

A Phase 2, Open Label Study of PEmigatinib and REtifanlimab in Advanced Dedifferentiated LIposarcoma (PERELI)

Recruiting
NCT03656536Phase 3

A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma

Terminated
NCT02924376Phase 2

Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202)

Completed
NCT02872714Phase 2

A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Urothelial Carcinoma - (FIGHT-201)

Completed
NCT05253807Phase 2

Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer With an FGFR Alteration

Completed
NCT06653777Phase 2

Efficacy of Pemigatinib in Patients With Solid Tumors Characterized by an Alteration of the Gene FGFR in Tumor Cells

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
43