Success Metrics

Clinical Success Rate
76.0%

Based on 79 completed trials

Completion Rate
76%(79/104)
Active Trials
60(31%)
Results Posted
95%(75 trials)
Terminated
25(13%)

Phase Distribution

Ph phase_1
63
32%
Ph phase_2
82
42%
Ph not_applicable
14
7%
Ph phase_3
27
14%
Ph early_phase_1
4
2%

Phase Distribution

67

Early Stage

82

Mid Stage

27

Late Stage

Phase Distribution190 total trials
Early Phase 1First-in-human
4(2.1%)
Phase 1Safety & dosage
63(33.2%)
Phase 2Efficacy & side effects
82(43.2%)
Phase 3Large-scale testing
27(14.2%)
N/ANon-phased studies
14(7.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

70.5%

79 of 112 finished

Non-Completion Rate

29.5%

33 ended early

Currently Active

60

trials recruiting

Total Trials

196

all time

Status Distribution
Active(66)
Completed(79)
Terminated(33)
Other(18)

Detailed Status

Completed79
Active, not recruiting38
Terminated25
Recruiting22
unknown14
Withdrawn8

Development Timeline

Analytics

Development Status

Total Trials
196
Active
60
Success Rate
76.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 14 (2.1%)
Phase 163 (33.2%)
Phase 282 (43.2%)
Phase 327 (14.2%)
N/A14 (7.4%)

Trials by Status

recruiting2211%
unknown147%
active_not_recruiting3819%
suspended42%
withdrawn84%
not_yet_recruiting63%
completed7940%
terminated2513%

Recent Activity

Clinical Trials (196)

Showing 20 of 196 trialsScroll for more
NCT04671667Phase 2

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recruiting
NCT00967863Not Applicable

Radiation Therapy in Treating Patients Receiving Hormone Therapy for Prostate Cancer (GETUG-AFU 18)

Active Not Recruiting
NCT03811002Phase 3

Testing the Addition of a New Immunotherapy Drug, Atezolizumab (MPDL3280A), to the Usual Chemoradiation (CRT) Therapy Treatment for Limited Stage Small Cell Lung Cancer (LS-SCLC)

Active Not Recruiting
NCT07061977Phase 3

Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

Recruiting
NCT06860594Phase 1

Testing the Addition of an Anti-Cancer Drug, Triapine, to the Usual Radiation Therapy for Recurrent Glioblastoma or Astrocytoma

Recruiting
NCT06568172Phase 3

Testing the Addition of an Immunotherapy Drug, Cemiplimab (REGN2810), Plus Surgery to the Usual Surgery Alone for Treating Advanced Skin Cancer

Suspended
NCT01810913Phase 2

Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer

Suspended
NCT03811015Phase 3

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Active Not Recruiting
NCT02595879Phase 1

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

Active Not Recruiting
NCT05384756Phase 1

TMLI and Alemtuzumab for Treatment of Sickle Cell Disease

Active Not Recruiting
NCT03180502Phase 2

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

Active Not Recruiting
NCT04615013Phase 1

NBTXR3, Chemotherapy, and Radiation Therapy for the Treatment of Esophageal Cancer

Recruiting
NCT03796767Phase 2

Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer

Completed
NCT05388773Phase 2

Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx Cancer

Recruiting
NCT06368817Phase 2

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

Recruiting
NCT05075980Phase 2

Intensity Modulated Proton or X-Ray Therapy After Surgery for Treatment of Head and Neck Cancer, the HEADLIGHT Study

Active Not Recruiting
NCT07579195Phase 1

Consolidative Therapy After EV + Pembrolizumab in Muscle Invasive Bladder Cancer, REINFORCE Trial

Not Yet Recruiting
NCT04158141Phase 3

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Terminated
NCT04166318Phase 2

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Active Not Recruiting
NCT02635009Phase 2

Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Limited Stage or Extensive Stage Small Cell Lung Cancer

Completed

Drug Details

Intervention Type
RADIATION
Total Trials
196