Success Metrics

Clinical Success Rate
80.0%

Based on 12 completed trials

Completion Rate
80%(12/15)
Active Trials
0(0%)
Results Posted
100%(12 trials)
Terminated
3(19%)

Phase Distribution

Ph phase_4
2
13%
Ph phase_1
2
13%
Ph phase_3
5
31%
Ph phase_2
7
44%

Phase Distribution

2

Early Stage

7

Mid Stage

7

Late Stage

Phase Distribution16 total trials
Phase 1Safety & dosage
2(12.5%)
Phase 2Efficacy & side effects
7(43.8%)
Phase 3Large-scale testing
5(31.3%)
Phase 4Post-market surveillance
2(12.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.0%

12 of 15 finished

Non-Completion Rate

20.0%

3 ended early

Currently Active

0

trials recruiting

Total Trials

16

all time

Status Distribution
Completed(12)
Terminated(3)
Other(1)

Detailed Status

Completed12
Terminated3
unknown1

Development Timeline

Analytics

Development Status

Total Trials
16
Active
0
Success Rate
80.0%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (12.5%)
Phase 27 (43.8%)
Phase 35 (31.3%)
Phase 42 (12.5%)

Trials by Status

completed1275%
unknown16%
terminated319%

Recent Activity

0 active trials
Showing 5 of 16
completedphase_3

A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)

NCT06059846
completedphase_3

Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis

NCT05887908
completedphase_1

To Evaluate the Pharmacokinetics of XNW4107 in Healthy Adult Young Females and in Healthy Adult Elderly Males and Females.

NCT04801043
completedphase_2

Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections

NCT03445195
completedphase_2

A Study of Efficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections

NCT02321800
View all 16 trials

Clinical Trials (16)

Showing 16 of 16 trials
NCT06059846Phase 3

A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)

Completed
NCT05887908Phase 3

Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis

Completed
NCT04801043Phase 1

To Evaluate the Pharmacokinetics of XNW4107 in Healthy Adult Young Females and in Healthy Adult Elderly Males and Females.

Completed
NCT03445195Phase 2

Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections

Completed
NCT02321800Phase 2

A Study of Efficacy and Safety of Intravenous Cefiderocol (S-649266) Versus Imipenem/Cilastatin in Complicated Urinary Tract Infections

Completed
NCT01506271Phase 2

Study of the Safety, Tolerability, and Efficacy of Relebactam (MK-7655) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone to Treat Complicated Intra-Abdominal Infection [cIAI] (MK-7655-004)

Completed
NCT00515034Phase 2

A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumonia

Completed
NCT02452047Phase 3

Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) Versus Colistimethate Sodium+Imipenem+Cilastatin in Imipenem-Resistant Bacterial Infection (MK-7655A-013)

Completed
NCT00690378Phase 2

Comparative Study of NXL104/Ceftazidime Versus Comparator in Adults With Complicated Urinary Tract Infections

Completed
NCT01721408Phase 4

A Study To Determine The Efficacy And Safety Of Tigecycline Compared With Imipenem/Cliastatin to Treat Complicated Intra-Abdominal Infection

Completed
NCT01381549Phase 2

GSK2251052 in Complicated Urinary Tract Infection

Terminated
NCT00619710Phase 3

Complicated Skin and Skin Structure Infections

Completed
NCT02971423Phase 1

Evaluation of the Safety, Tolerability and Pharmacokinetics of Intravenous ETX2514 Administered in Healthy Subjects

Completed
NCT00589693Phase 3

To Compare Safety and Efficacy of Doripenem Versus Imipenem-Cilastatin in Patients With Ventilator-Associated Pneumonia

Terminated
NCT00707239Phase 2

Study Evaluating Safety and Efficacy of Tigecycline Versus Imipenem/Cilastatin Subjects With Hospital-Acquired Pneumonia

Terminated
NCT01356472Phase 4

Linezolid Alone or Combined With Carbapenem Against Methicillin-resistant Staphylococcus Aureus (MRSA) in Ventilator-associated Pneumonia

Unknown

All 16 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
16