Success Metrics

Clinical Success Rate

92.6%

Based on 25 completed trials

Completion Rate

93%(25/27)

Active Trials

2(6%)

Results Posted

48%(12 trials)

Terminated

2(6%)

Phase Distribution

Ph not_applicable

14%

Ph phase_4

26%

Ph phase_1

Ph early_phase_1

Ph phase_3

23%

Ph phase_2

20%

Phase Distribution

Early Stage

Mid Stage

Late Stage

Phase Distribution32 total trials

Early Phase 1First-in-human

1(3.1%)

Phase 1Safety & dosage

2(6.3%)

Phase 2Efficacy & side effects

7(21.9%)

Phase 3Large-scale testing

8(25.0%)

Phase 4Post-market surveillance

9(28.1%)

N/ANon-phased studies

5(15.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

80.6%

25 of 31 finished

Non-Completion Rate

19.4%

6 ended early

Currently Active

trials recruiting

Total Trials

all time

Status Distribution

Active(2)

Completed(25)

Terminated(6)

Other(2)

Detailed Status

Completed25

Withdrawn4

Terminated2

Recruiting2

unknown1

Suspended1

Development Timeline

Analytics

Development Status

Total Trials

Active

Success Rate

92.6%

Most Advanced

Phase 4

Trials by Phase

Early Phase 11 (3.1%)

Phase 12 (6.3%)

Phase 27 (21.9%)

Phase 38 (25.0%)

Phase 49 (28.1%)

N/A5 (15.6%)

Trials by Status

terminated26%

completed2571%

unknown13%

withdrawn411%

recruiting26%

suspended13%

Recent Activity

2 active trials

Showing 5 of 35

completedearly_phase_1

Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.

NCT06287580

recruitingphase_4

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

NCT05593055

recruitingphase_4

Clinical Trials (35)

Showing 20 of 35 trialsScroll for more

NCT06287580Early Phase 1

Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.

Completed

NCT05593055Phase 4

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

Recruiting

NCT07225764Phase 4

CaOx Stone Prevention

Recruiting

NCT05915286Phase 4

Diuretic Use in Hemodialysis Patients With Residual Renal Function

Suspended

NCT00006294

Genetics of Hypertension Associated Treatments (GenHAT)

Completed

NCT02665117Not Applicable

Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Completed

NCT05275907Phase 4

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

Withdrawn

NCT05222191Phase 2

Spironolactone in CKD Enabled by Chlorthalidone: PILOT

Unknown

NCT02841280Phase 2

Chlorthalidone in Chronic Kidney Disease

Completed

NCT02711670Not Applicable

Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium

Completed

NCT04757532Phase 1

Study of Exposure to Substances Prohibited by the World Anti-Doping Agency in Healthy Volunteers.

Completed

NCT03325114Phase 2

Safety and Efficacy of Chlorthalidone in Type 1 Diabetes

Terminated

NCT03923933Phase 2

Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial

Completed

NCT02357004Not Applicable

Mechanisms of Refractory Hypertension (Carvedilol)

Withdrawn

NCT02236520Phase 2

Tissue Sodium in Pre-hypertensive Patients

Completed

NCT01083017

Resistant Arterial Hypertension Cohort Study

Completed

NCT03560804Not Applicable

Use of Impedance Cardiography and Applanation Tonometry for Prediction of the Antihypertensive Effect of Two Drugs

Completed

NCT01203852Phase 4

Pharmacogenomic Evaluation of Antihypertensive Responses 2

Completed

NCT01748123Phase 4

EBMtrialcentral- Comparing Initial Diuretic Therapies Using a Collaborative Network

Withdrawn

NCT02644395Phase 3

Thiazide Diuretics for Hypertension in Kidney Transplant Recipients Using Tacrolimus

Completed

Drug Details

Intervention Type: DRUG
Total Trials: 35