Success Metrics

Clinical Success Rate
89.3%

Based on 25 completed trials

Completion Rate
89%(25/28)
Active Trials
2(6%)
Results Posted
48%(12 trials)
Terminated
3(9%)

Phase Distribution

Ph phase_3
8
23%
Ph phase_4
9
26%
Ph not_applicable
5
14%
Ph early_phase_1
1
3%
Ph phase_1
2
6%
Ph phase_2
7
20%

Phase Distribution

3

Early Stage

7

Mid Stage

17

Late Stage

Phase Distribution32 total trials
Early Phase 1First-in-human
1(3.1%)
Phase 1Safety & dosage
2(6.3%)
Phase 2Efficacy & side effects
7(21.9%)
Phase 3Large-scale testing
8(25.0%)
Phase 4Post-market surveillance
9(28.1%)
N/ANon-phased studies
5(15.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

78.1%

25 of 32 finished

Non-Completion Rate

21.9%

7 ended early

Currently Active

2

trials recruiting

Total Trials

35

all time

Status Distribution
Active(2)
Completed(25)
Terminated(7)
Other(1)

Detailed Status

Completed25
Withdrawn4
Terminated3
Recruiting2
unknown1

Development Timeline

Analytics

Development Status

Total Trials
35
Active
2
Success Rate
89.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (3.1%)
Phase 12 (6.3%)
Phase 27 (21.9%)
Phase 38 (25.0%)
Phase 49 (28.1%)
N/A5 (15.6%)

Trials by Status

unknown13%
terminated39%
withdrawn411%
completed2571%
recruiting26%

Recent Activity

2 active trials
Showing 5 of 35
terminatedphase_4

Diuretic Use in Hemodialysis Patients With Residual Renal Function

NCT05915286
completedearly_phase_1

Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.

NCT06287580
recruitingphase_4

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

NCT05593055
recruitingphase_4

CaOx Stone Prevention

NCT07225764
completed

Genetics of Hypertension Associated Treatments (GenHAT)

NCT00006294
View all 35 trials

Clinical Trials (35)

Showing 20 of 35 trialsScroll for more
NCT05915286Phase 4

Diuretic Use in Hemodialysis Patients With Residual Renal Function

Terminated
NCT06287580Early Phase 1

Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension.

Completed
NCT05593055Phase 4

Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

Recruiting
NCT07225764Phase 4

CaOx Stone Prevention

Recruiting
NCT00006294

Genetics of Hypertension Associated Treatments (GenHAT)

Completed
NCT02665117Not Applicable

Preventing Metabolic Side Effects of Thiazide Diuretics With KMgCitrate

Completed
NCT05275907Phase 4

Mechanism of Hypertension Treatments in Liver Transplant Recipients (BLOCK LTR-HTN)

Withdrawn
NCT05222191Phase 2

Spironolactone in CKD Enabled by Chlorthalidone: PILOT

Unknown
NCT02841280Phase 2

Chlorthalidone in Chronic Kidney Disease

Completed
NCT02711670Not Applicable

Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium

Completed
NCT04757532Phase 1

Study of Exposure to Substances Prohibited by the World Anti-Doping Agency in Healthy Volunteers.

Completed
NCT03325114Phase 2

Safety and Efficacy of Chlorthalidone in Type 1 Diabetes

Terminated
NCT03923933Phase 2

Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial

Completed
NCT02357004Not Applicable

Mechanisms of Refractory Hypertension (Carvedilol)

Withdrawn
NCT02236520Phase 2

Tissue Sodium in Pre-hypertensive Patients

Completed
NCT01083017

Resistant Arterial Hypertension Cohort Study

Completed
NCT03560804Not Applicable

Use of Impedance Cardiography and Applanation Tonometry for Prediction of the Antihypertensive Effect of Two Drugs

Completed
NCT01203852Phase 4

Pharmacogenomic Evaluation of Antihypertensive Responses 2

Completed
NCT01748123Phase 4

EBMtrialcentral- Comparing Initial Diuretic Therapies Using a Collaborative Network

Withdrawn
NCT02644395Phase 3

Thiazide Diuretics for Hypertension in Kidney Transplant Recipients Using Tacrolimus

Completed

Drug Details

Intervention Type
DRUG
Total Trials
35