Success Metrics

Clinical Success Rate
82.9%

Based on 29 completed trials

Completion Rate
83%(29/35)
Active Trials
6(14%)
Results Posted
69%(20 trials)
Terminated
6(14%)

Phase Distribution

Ph phase_1
16
37%
Ph phase_3
5
12%
Ph phase_2
14
33%
Ph not_applicable
1
2%
Ph phase_4
2
5%

Phase Distribution

16

Early Stage

14

Mid Stage

7

Late Stage

Phase Distribution38 total trials
Phase 1Safety & dosage
16(42.1%)
Phase 2Efficacy & side effects
14(36.8%)
Phase 3Large-scale testing
5(13.2%)
Phase 4Post-market surveillance
2(5.3%)
N/ANon-phased studies
1(2.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

82.9%

29 of 35 finished

Non-Completion Rate

17.1%

6 ended early

Currently Active

6

trials recruiting

Total Trials

43

all time

Status Distribution
Active(6)
Completed(29)
Terminated(6)
Other(2)

Detailed Status

Completed29
Terminated6
Active, not recruiting3
Recruiting3
unknown2

Development Timeline

Analytics

Development Status

Total Trials
43
Active
6
Success Rate
82.9%
Most Advanced
Phase 4

Trials by Phase

Phase 116 (42.1%)
Phase 214 (36.8%)
Phase 35 (13.2%)
Phase 42 (5.3%)
N/A1 (2.6%)

Trials by Status

completed2967%
active_not_recruiting37%
recruiting37%
terminated614%
unknown25%

Recent Activity

Clinical Trials (43)

Showing 20 of 43 trialsScroll for more
NCT03297606Phase 2

Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR)

Recruiting
NCT04971226Phase 3

A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP

Active Not Recruiting
NCT04877522Phase 4

Asciminib Roll-over Study

Recruiting
NCT03654768Phase 2

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Active Not Recruiting
NCT04258943Phase 1

Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia

Active Not Recruiting
NCT03831776Phase 2

Long-acting Low Dose Ropeginterferon for Chronic Myeloid Leukemia Treated With Bosutinib From Diagnosis

Completed
NCT06423911Phase 3

Study of Olverembatinib (HQP1351) in Patients With CP-CML

Recruiting
NCT03106779Phase 3

Study of Efficacy of CML-CP Patients Treated With ABL001 Versus Bosutinib, Previously Treated With 2 or More TKIs

Completed
NCT03854903Phase 1

WI231696: Bosutinib, Palbocicilib and Fulvestrant for HR+HER2- Advanced Breast Cancer Refractory to a CDK4/6 Inhibitor

Completed
NCT05032690Phase 1

Evaluation of the Relative Bioavailability of Bosutinib Capsules Under Fed Condition and Estimation of Food Effect on Orally Administered Bosutinib Capsule

Completed
NCT02501330

Safety And Efficacy Of Bosutinib

Completed
NCT05286528

Study to Evaluate Chronic Myeloid Leukemia Treatment Landscape and Real-life Treatment Outcomes in Hungary: Analysis of National Health Insurance Fund Database

Completed
NCT02546375

A Study To Describe The Real World Use Of Bosutinib In The UK And Netherlands

Completed
NCT02311998Phase 1

Phase I/II Study of Bosutinib in Combination With Inotuzumab Ozogamicin in CD22-positive PC Positive ALL and CML

Completed
NCT05363488

Retrospective Observational Research Study to Describe the Real World Use of Bosutinib in a Single Centre in Scotland

Completed
NCT02810990Phase 2

Bosutinib in Elderly Chronic Myeloid Leukemia

Completed
NCT03885830

Precision Dosing of Tyrosine Kinase Inhibitors in CML Patients

Completed
NCT02921477Phase 1

Study for the Use of TKIs for Treatment of Cognitive Decline Due to Degenerative Dementias

Unknown
NCT01903733Not Applicable

Bosutinib Treatment Extension Study Only For Subjects With Chronic Myeloid Leukemia (CML) Who Have Previously Participated In Bosutinib Studies B1871006 Or B1871008

Completed
NCT03023319Phase 1

Bosutinib in Combination With Pemetrexed in Patients With Selected Metastatic Solid Tumors

Completed

Drug Details

Intervention Type
DRUG
Total Trials
43