Success Metrics

Clinical Success Rate
80.8%

Based on 84 completed trials

Completion Rate
81%(84/104)
Active Trials
29(16%)
Results Posted
57%(48 trials)
Terminated
20(11%)

Phase Distribution

Ph phase_3
24
13%
Ph early_phase_1
1
1%
Ph phase_2
102
57%
Ph not_applicable
5
3%
Ph phase_4
2
1%
Ph phase_1
44
25%

Phase Distribution

45

Early Stage

102

Mid Stage

26

Late Stage

Phase Distribution178 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
44(24.7%)
Phase 2Efficacy & side effects
102(57.3%)
Phase 3Large-scale testing
24(13.5%)
Phase 4Post-market surveillance
2(1.1%)
N/ANon-phased studies
5(2.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.7%

84 of 111 finished

Non-Completion Rate

24.3%

27 ended early

Currently Active

29

trials recruiting

Total Trials

179

all time

Status Distribution
Active(38)
Completed(84)
Terminated(27)
Other(30)

Detailed Status

Completed84
unknown29
Recruiting20
Terminated20
Not yet recruiting9
Active, not recruiting9

Development Timeline

Analytics

Development Status

Total Trials
179
Active
29
Success Rate
80.8%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.6%)
Phase 144 (24.7%)
Phase 2102 (57.3%)
Phase 324 (13.5%)
Phase 42 (1.1%)
N/A5 (2.8%)

Trials by Status

unknown2916%
recruiting2011%
not_yet_recruiting95%
completed8447%
active_not_recruiting95%
terminated2011%
withdrawn74%
suspended11%

Recent Activity

Clinical Trials (179)

Showing 20 of 179 trialsScroll for more
NCT04776655Phase 3

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

Active Not Recruiting
NCT07673887Phase 3

A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer

Recruiting
NCT04210115Phase 3

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

Completed
NCT04949256Phase 3

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014)

Completed
NCT07024615Phase 1

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

Recruiting
NCT06741644Phase 1

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

Recruiting
NCT04083599Phase 1

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Active Not Recruiting
NCT06535607Phase 2

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

Recruiting
NCT07056777Phase 1

Evaluation of the Preliminary Efficacy and Safety of DR30206 in Combination With Standard Therapy in Patients With Gastrointestinal Cancer

Recruiting
NCT07532902Phase 1

A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

Recruiting
NCT04150640Phase 2

Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric Adenocarcinoma

Recruiting
NCT03872947Phase 1

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Active Not Recruiting
NCT04607421Phase 3

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Active Not Recruiting
NCT05235542Phase 1

A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors

Completed
NCT02710734Phase 2

Risk Enabled Therapy After Initiating Neoadjuvant Chemotherapy for Bladder Cancer (RETAIN)

Completed
NCT04662710Phase 3

Efficacy and Safety of Lenvatinib (E7080/MK-7902) Plus Pembrolizumab (MK-3475) Plus Chemotherapy in Participants With Advanced/Metastatic Gastroesophageal Adenocarcinoma (MK-7902-015/E7080-G000-321/LEAP-015)

Completed
NCT07484724Phase 2

A Study Evaluating the Safety and Efficacy of JS212 Combination Therapy in Patients With Advanced Esophageal Squamous Cell Carcinoma

Recruiting
NCT02143219Phase 2

Efficacy and Tolerance Evaluation in FOLFIRINOX Dose Adjusted in Elderly Patients With a Metastatic Pancreatic Cancer

Completed
NCT05945823Phase 2

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

Active Not Recruiting
NCT07474727Phase 2

A Phase II Study of AMT-676 Combination Therapies in Advanced Colorectal Cancer

Not Yet Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
179