Success Metrics

Clinical Success Rate
79.0%

Based on 83 completed trials

Completion Rate
79%(83/105)
Active Trials
31(17%)
Results Posted
59%(49 trials)
Terminated
22(12%)

Phase Distribution

Ph not_applicable
5
3%
Ph early_phase_1
1
1%
Ph phase_4
2
1%
Ph phase_3
26
14%
Ph phase_1
44
24%
Ph phase_2
102
56%

Phase Distribution

45

Early Stage

102

Mid Stage

28

Late Stage

Phase Distribution180 total trials
Early Phase 1First-in-human
1(0.6%)
Phase 1Safety & dosage
44(24.4%)
Phase 2Efficacy & side effects
102(56.7%)
Phase 3Large-scale testing
26(14.4%)
Phase 4Post-market surveillance
2(1.1%)
N/ANon-phased studies
5(2.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

74.1%

83 of 112 finished

Non-Completion Rate

25.9%

29 ended early

Currently Active

31

trials recruiting

Total Trials

181

all time

Status Distribution
Active(39)
Completed(83)
Terminated(29)
Other(30)

Detailed Status

Completed83
unknown29
Recruiting22
Terminated22
Active, not recruiting9
Not yet recruiting8

Development Timeline

Analytics

Development Status

Total Trials
181
Active
31
Success Rate
79.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.6%)
Phase 144 (24.4%)
Phase 2102 (56.7%)
Phase 326 (14.4%)
Phase 42 (1.1%)
N/A5 (2.8%)

Trials by Status

withdrawn74%
suspended11%
not_yet_recruiting84%
completed8346%
active_not_recruiting95%
recruiting2212%
terminated2212%
unknown2916%

Recent Activity

Clinical Trials (181)

Showing 20 of 181 trialsScroll for more
NCT07829783Phase 3

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) and Pembrolizumab (MK-3475A) in Participants With Bladder Cancer (MK-2870-055)

Not Yet Recruiting
NCT07532902Phase 1

A Study of BMS-986504 With Standard-of-Care Therapy for People With Solid Tumor Cancer

Recruiting
NCT06730373Phase 2

First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2)

Recruiting
NCT07673887Phase 3

A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer

Recruiting
NCT06535607Phase 2

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

Recruiting
NCT07775287Phase 3

Study of Petosemtamab Plus Chemotherapy Versus Cetuximab or Bevacizumab Plus Chemotherapy in RAS and BRAF Wild Type, Recurrent, Unresectable or Metastatic Colorectal Cancer (LiGeR-CRC2)

Recruiting
NCT07024615Phase 1

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

Recruiting
NCT05945823Phase 2

Phase 2 Futibatinib in Combination With PD-1 Antibody Based Standard of Care in Solid Tumors

Active Not Recruiting
NCT03366155Phase 2

Hepatic Artery Infusion Pump Chemotherapy With Floxuridine and Dexamethasone in Combination With Systemic Chemotherapy for Patients With Colorectal Cancer Metastatic to the Liver

Completed
NCT04034173Phase 2

Optimal Anti-EGFR Treatment of mCRC Patients With Low-Frequency RAS Mutation

Terminated
NCT07474727Phase 2

A Phase II Study of AMT-676 Combination Therapies in Advanced Colorectal Cancer

Recruiting
NCT03615326Phase 3

Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Advanced Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (MK-3475-811/KEYNOTE-811)

Completed
NCT04949256Phase 3

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) Plus Chemotherapy in Participants With Metastatic Esophageal Carcinoma (MK-7902-014/E7080-G000-320/LEAP-014).

Terminated
NCT06741644Phase 1

A Phase I/II Study of CS2009 in Participants With Advanced Solid Tumors

Recruiting
NCT04083599Phase 1

GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors

Active Not Recruiting
NCT04776655Phase 3

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

Active Not Recruiting
NCT04210115Phase 3

Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Who Are Receiving Chemotherapy and Radiation Therapy (MK-3475-975/KEYNOTE-975)

Completed
NCT07056777Phase 1

Evaluation of the Preliminary Efficacy and Safety of DR30206 in Combination With Standard Therapy in Patients With Gastrointestinal Cancer

Recruiting
NCT04150640Phase 2

Oxaliplatin and Liposomal Irinotecan (Plus Trastuzumab for HER2-positive Disease) in Advanced Esophageal and Gastric Adenocarcinoma

Recruiting
NCT03872947Phase 1

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
181