Key Insights

Highlights

Success Rate

70% trial completion

Published Results

25 trials with published results (24%)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 37/100

Termination Rate

14.6%

15 terminated out of 103 trials

Success Rate

70.0%

-16.6% vs benchmark

Late-Stage Pipeline

16%

16 trials in Phase 3/4

Results Transparency

71%

25 of 35 completed with results

Key Signals

25 with results70% success15 terminated

Data Visualizations

Phase Distribution

84Total
Not Applicable (21)
Early P 1 (4)
P 1 (20)
P 2 (23)
P 3 (13)
P 4 (3)

Trial Status

Completed35
Recruiting19
Terminated15
Unknown13
Not Yet Recruiting10
Active Not Recruiting9

Trial Success Rate

70.0%

Benchmark: 86.6%

Based on 35 completed trials

Clinical Trials (103)

Showing 20 of 20 trials
NCT05944237Phase 1Recruiting

HTL0039732 in Participants With Advanced Solid Tumours

NCT06833073Phase 2RecruitingPrimary

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

NCT07566156Phase 3Recruiting

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

NCT05007106Phase 2Completed

MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

NCT04658862Phase 3Active Not RecruitingPrimary

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

NCT07735793Not Yet RecruitingPrimary

A Study of Radical Cystectomy in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) and Muscle Invasive Bladder Cancer (MIBC) in Korea

NCT04640623Phase 2Active Not RecruitingPrimary

A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy

NCT07218380Phase 3Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

NCT07804056Phase 3RecruitingPrimary

A Study to Investigate the Efficacy and Safety of Alpha1H as a Neoadjuvant Therapy in Participants With Low- to Intermediate-Risk/Low-Grade Papillary Non-Muscle Invasive Bladder Cancer

NCT07827612Phase 2Not Yet RecruitingPrimary

A Study of Vepugratinib (LY3866288) in Adults With Non-Muscle Invasive Bladder Cancer and Upper Tract Urothelial Cancer

NCT05014139Phase 1TerminatedPrimary

A Study of Intravesical Enfortumab Vedotin For Treatment of Patients With Non-muscle Invasive Bladder Cancer (NMIBC)

NCT07222488Phase 1Recruiting

A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

NCT03661320Phase 3CompletedPrimary

A Study to Compare Chemotherapy Alone Versus Chemotherapy Plus Nivolumab or Nivolumab and BMS-986205, Followed by Continued Therapy After Surgery With Nivolumab or Nivolumab and BMS-986205 in Participants With Muscle Invasive Bladder Cancer

NCT07189793Phase 2Not Yet RecruitingPrimary

Toripalimab ± Sequential Intravesical Gemcitabine-Mitomycin C for BCG-Unresponsive/-Intolerant High-Risk NMIBC: Open-Label Randomized Phase 2 Study

NCT07784387RecruitingPrimary

A Study to Characterize High-Risk Non-Muscle-Invasive Bladder Cancer Participants in Portugal

NCT05567185Phase 1Active Not RecruitingPrimary

A Study of Erdafitinib Intravesical Delivery System in Japanese Participants With Bladder Cancer

NCT03258593Phase 1CompletedPrimary

Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)

NCT05614739Phase 1RecruitingPrimary

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

NCT03459846Phase 2Active Not RecruitingPrimary

A Study of Durvalumab Alone and Durvalumab+Olaparib in Advanced, Platinum-Ineligible Bladder Cancer (BAYOU)

NCT06960577Phase 3RecruitingPrimary

Perioperative Durvalumab With Neoadjuvant ddMVAC or Gemcitabine/Cisplatin in Patients With Muscle-invasive Bladder Cancer (NIAGARA-2)

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