Key Insights

Highlights

Success Rate

65% trial completion

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 49/100

Termination Rate

16.2%

6 terminated out of 37 trials

Success Rate

64.7%

-21.8% vs benchmark

Late-Stage Pipeline

11%

4 trials in Phase 3/4

Results Transparency

45%

5 of 11 completed with results

Key Signals

5 with results65% success

Data Visualizations

Phase Distribution

21Total
Not Applicable (15)
Early P 1 (1)
P 2 (1)
P 3 (3)
P 4 (1)

Trial Status

Completed11
Unknown10
Recruiting7
Terminated6
Not Yet Recruiting2
Withdrawn1

Trial Success Rate

64.7%

Benchmark: 86.5%

Based on 11 completed trials

Clinical Trials (37)

Showing 20 of 20 trials
NCT06498960Not ApplicableRecruitingPrimary

Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

NCT05910944RecruitingPrimary

European Study of Prodromal iNPH

NCT04471740Not ApplicableRecruitingPrimary

Normal Pressure Hydrocephalus and Sleep Apnea

NCT06724029Recruiting

Neurosurgical Outcome Network

NCT07103681RecruitingPrimary

White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH)

NCT06857136Completed

The Role of the Glymphatic System Avaluated Thourgh mr Imaging in the Diagnosis and Management of NPH

NCT02016352Not ApplicableCompletedPrimary

Cerebrospinal Fluid Proteome in Hydrocephalus

NCT01815775Early Phase 1CompletedPrimary

Predictive Value of Flow MRI in Normal Pressure Hydrocephalus Surgery

NCT07172841Not ApplicableNot Yet Recruiting

Non-invasive Diagnostics of Shunt Obstruction in Adult Hydrocephalus

NCT06426004Not ApplicableNot Yet RecruitingPrimary

Addressing Health Disparities in Normal Pressure Hydrocephalus (NPH) in Maryland

NCT04020198Terminated

A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies

NCT06629168Completed

The Usage of Telemetric Prechamber Sensor Reservoir in Management of Normal Pressure Hydrocephalus. Comparisson of Benefit for Patients with Implanted Telemetric Prechamber Sensor Reservoir.

NCT06528964Recruiting

Proteinopathies Expression in Skin of Neurodegenerative Disorders

NCT06722768RecruitingPrimary

Identifying Gait Changes From a CSF Tap Test Using a Smart Insole in iNPH

NCT03521518TerminatedPrimary

CPT-3 in Normal Pressure Hydrocephalus

NCT05562596UnknownPrimary

Normal Pressure Hydrocephalus Biomarkers Investigation

NCT03826056Not ApplicableCompleted

Neurology Inpatient Clinical Education Trial

NCT03269201Unknown

Brain Network Activation in Patients With Movement Disorders

NCT00613886Not ApplicableTerminatedPrimary

Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus

NCT04434053Not ApplicableUnknownPrimary

Adjustable Gravitational vs. Adjustable Differential Pressure Valves in iNPH

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