Key Insights

Highlights

Success Rate

83% trial completion

Published Results

55 trials with published results (18%)

Research Maturity

187 completed trials (60% of total)

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

12.4%

39 terminated out of 314 trials

Success Rate

82.7%

-3.8% vs benchmark

Late-Stage Pipeline

14%

44 trials in Phase 3/4

Results Transparency

29%

55 of 187 completed with results

Key Signals

55 with results83% success39 terminated

Data Visualizations

Phase Distribution

270Total
Not Applicable (43)
Early P 1 (1)
P 1 (101)
P 2 (81)
P 3 (34)
P 4 (10)

Trial Status

Completed187
Unknown44
Terminated39
Recruiting15
Withdrawn14
Active Not Recruiting10

Trial Success Rate

82.7%

Benchmark: 86.6%

Based on 187 completed trials

Clinical Trials (314)

Showing 20 of 20 trials
NCT05103358Phase 2Completed

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

NCT07114601Phase 1Recruiting

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

NCT07213804Phase 3Recruiting

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

NCT07174336Phase 3Recruiting

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

NCT07218380Phase 3Recruiting

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

NCT07824856Phase 2Not Yet Recruiting

Local Ablation Plus Systemic Therapy for Metachronous Liver and/or Lung Oligometastases From Nasopharyngeal Carcinoma

NCT05573893Recruiting

PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan

NCT06119581Phase 3Recruiting

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

NCT00781612Phase 2Active Not RecruitingPrimary

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

NCT06460961Phase 1CompletedPrimary

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

NCT02892305Active Not Recruiting

Hepatic Resection for Metastatic Pancreatic Cancer

NCT05614739Phase 1Recruiting

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

NCT04886804Phase 1Active Not RecruitingPrimary

Beamion LUNG-1: A Study to Test Different Doses of Zongertinib in People With Different Types of Advanced Cancer (Solid Tumours With Changes in the HER2 Gene)

NCT07151586Phase 2Not Yet Recruiting

Testing Two Different Drugs (Sacituzumab-govitecan and Trastuzumab-deruxtecan) Combinations Prescribed in an Alterning Pattern to Patients With Metastatic or Locally Advanced Triple-negative Breast Cancer

NCT07697989Not Yet Recruiting

Pluvicto Real-world Investigation in Survival in Metastatic CRPC

NCT04975308Phase 3Active Not Recruiting

A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer

NCT00317720Phase 1Completed

Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 (HER-2) Overexpressing Breast Cancer

NCT05288166Phase 3Active Not Recruiting

A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer)

NCT07675057Unknown

Expanded Access for Vepugratinib (LY3866288) in Participants With Fibroblast Growth Factor Receptor 3 (FGFR3) Altered Solid Tumors

NCT07046923Phase 1Recruiting

A Study of LY4175408 in Participants With Advanced Cancer

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