Key Insights

Highlights

Success Rate

50% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 60/100

Termination Rate

13.3%

2 terminated out of 15 trials

Success Rate

50.0%

-36.5% vs benchmark

Late-Stage Pipeline

7%

1 trials in Phase 3/4

Results Transparency

100%

2 of 2 completed with results

Key Signals

2 with results50% success

Data Visualizations

Phase Distribution

15Total
P 1 (6)
P 2 (8)
P 3 (1)

Trial Status

Recruiting5
Unknown4
Completed2
Terminated2
Active Not Recruiting1
Not Yet Recruiting1

Trial Success Rate

50.0%

Benchmark: 86.5%

Based on 2 completed trials

Clinical Trials (15)

Showing 15 of 15 trials
NCT07452458Phase 3Not Yet Recruiting

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

NCT04396860Phase 2Completed

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

NCT06186401Phase 1Recruiting

Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells

NCT06504381Phase 1Recruiting

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

NCT05236036Phase 1Active Not Recruiting

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

NCT05879250Phase 2Recruiting

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

NCT06991101Phase 2Recruiting

Ruxolitinib With Radiation and Temozolomide Compared to Radiation and Temozolomide for Newly Diagnosed Glioblastoma

NCT03107780Phase 1Terminated

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

NCT05909618Phase 2Recruiting

Crizanlizumab Alone or in Combination With Nivolumab for Glioblastoma and Melanoma With Brain Metastases

NCT03452930Phase 1Completed

Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

NCT03250299Phase 1Terminated

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

NCT05694416Phase 2UnknownPrimary

Etoposide Plus Cisplatin Compared With Temozolomide in Patients With Glioblastoma

NCT05033587Phase 2UnknownPrimary

Study of AK105 With Anlotinib and Radiotherapy Adjuvant Therapy in MGMT Unmethylated Newly Diagnosed Glioblastoma.

NCT04725214Phase 2UnknownPrimary

Anlotinib Combined With STUPP for MGMT Nonmethylated Glioblastoma

NCT04224441Phase 2Unknown

Repurposing Chlorpromazine in the Treatment of Glioblastoma

Showing all 15 trials

Research Network

Activity Timeline