Key Insights

Highlights

Success Rate

91% trial completion (above average)

Published Results

53 trials with published results (17%)

Research Maturity

158 completed trials (51% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

5.1%

16 terminated out of 312 trials

Success Rate

90.8%

+4.2% vs benchmark

Late-Stage Pipeline

25%

77 trials in Phase 3/4

Results Transparency

34%

53 of 158 completed with results

Key Signals

53 with results91% success16 terminated

Data Visualizations

Phase Distribution

239Total
Not Applicable (54)
Early P 1 (5)
P 1 (56)
P 2 (47)
P 3 (36)
P 4 (41)

Trial Status

Completed158
Unknown45
Recruiting37
Active Not Recruiting26
Terminated16
Not Yet Recruiting14

Trial Success Rate

90.8%

Benchmark: 86.6%

Based on 158 completed trials

Clinical Trials (312)

Showing 20 of 20 trials
NCT05459077Not ApplicableNot Yet Recruiting

Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression

NCT04150068Phase 2Active Not RecruitingPrimary

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With an Optimized Background Regimen (OBR) in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance

NCT06987318Phase 1Not Yet RecruitingPrimary

A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection

NCT06532656Phase 2Active Not RecruitingPrimary

Study of Bictegravir/Lenacapavir in Children and Adolescents With HIV-1

NCT07357584Phase 4RecruitingPrimary

Efficacy and Safety of Doravirine in the Rapid Initiation

NCT04553081Phase 4CompletedPrimary

2DR Versus 3DR in a Prospective Randomized Controlled Switch Trial

NCT05973825Not ApplicableRecruitingPrimary

Immuno-virological Evaluation of Persons Living With HIV (PLWH)

NCT07616739Phase 4RecruitingPrimary

Dolutegravir/Lamivudine in Treatment-Naïve Pregnant Women

NCT05668026Phase 1RecruitingPrimary

Administration of Venetoclax to Promote Apoptosis of HIV-infected Cells and Reduce the Size of the HIV Reservoir Among People Living With HIV on ART

NCT04255849Phase 3Active Not Recruiting

Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV

NCT06358885Not ApplicableActive Not RecruitingPrimary

IGHID 12230 - An Implementation Trial of an Experiential Brief Alcohol Intervention for HIV Prevention

NCT06337032Phase 4RecruitingPrimary

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

NCT07708727Phase 2RecruitingPrimary

Study of an Injectable Regimen of GS-3242 With Lenacapavir Compared to Biktarvy in People New to HIV-1 Treatment

NCT06843902Phase 2RecruitingPrimary

Improving Coronary Vascular Health in Women

NCT05314088Not ApplicableCompleted

Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging With HIV

NCT07645287Phase 2RecruitingPrimary

A Study of GS-3242 in Combination With Lenacapavir Versus Biktarvy in Virologically Suppressed People With HIV-1

NCT07743593Phase 3Not Yet Recruiting

Optimizing Care for Cryptococcal Antigenemia: Evaluation of Short Course Fluconazole and ART Timing Among CrAg+ Persons With Low Titers

NCT05652400CompletedPrimary

HIV Transmission in the Era of Scaling up Antiretroviral Therapy in Ethiopia

NCT06071767Phase 1SuspendedPrimary

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

NCT04553211Not ApplicableCompletedPrimary

Expedited Partner Therapy and the HIV Prevention Cascade

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