Key Insights

Highlights

Success Rate

92% trial completion (above average)

Published Results

48 trials with published results (16%)

Research Maturity

150 completed trials (49% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 40/100

Termination Rate

4.3%

13 terminated out of 305 trials

Success Rate

92.0%

+5.5% vs benchmark

Late-Stage Pipeline

24%

74 trials in Phase 3/4

Results Transparency

32%

48 of 150 completed with results

Key Signals

48 with results92% success13 terminated

Data Visualizations

Phase Distribution

233Total
Not Applicable (54)
Early P 1 (5)
P 1 (55)
P 2 (45)
P 3 (34)
P 4 (40)

Trial Status

Completed150
Unknown48
Recruiting37
Active Not Recruiting30
Not Yet Recruiting14
Terminated13

Trial Success Rate

92.0%

Benchmark: 86.5%

Based on 150 completed trials

Clinical Trials (305)

Showing 20 of 20 trials
NCT05004038Phase 2CompletedPrimary

BCG Vaccination Effect on Latent Reservoir Size in Treated HIV-1 Infection:

NCT04883255Early Phase 1RecruitingPrimary

Cannabis Use, Cognition, and the Endocannabinoid System in HIV

NCT06630286Phase 3Active Not RecruitingPrimary

Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People With HIV-1

NCT05584397Enrolling By InvitationPrimary

Comparing Immune Activation and Latent HIV Reservoir Size Between People Living With HIV on Tenofovir-containing Versus NRTI-free ART

NCT04174755Not ApplicableRecruiting

Semaglutide's Efficacy in Achieving Weight Loss for Those With HIV

NCT05890963Phase 1Active Not RecruitingPrimary

10E8.4/iMab Bispecific Antibody and VRC07-523LS Monoclonal Antibody in HIV-infected Adults

NCT06749054Phase 2RecruitingPrimary

Evaluation of Long-Acting Lenacapavir for the Treatment of HIV-1 in Treatment-experienced Adolescents and Children

NCT05660980Phase 1RecruitingPrimary

Study of Oral and Long-Acting Injectable Cabotegravir and Rilpivirine in Virologically Suppressed Children Living With HIV-1, Two to Less Than 12 Years of Age

NCT06544733Phase 2Active Not RecruitingPrimary

Study of Oral Weekly Lepetegravir (Formerly GS-1720) and Lenacapavir Pacfosacil (Formerly GS-4182) Versus Biktarvy in People With HIV-1 Who Are Virologically Suppressed

NCT07055451Phase 1Active Not RecruitingPrimary

Study of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Newborns Exposed to HIV

NCT06613685Phase 2TerminatedPrimary

Study of Oral Weekly GS-1720 and GS-4182 Compared With Biktarvy in People With HIV-1 Who Have Not Been Treated

NCT06444620Phase 3Active Not RecruitingPrimary

B/F/TAF to DTG/3TC Switch Study

NCT05471076Phase 1Active Not RecruitingPrimary

Trial to Evaluate the Safety and Immunogenicity of Priming Regimens of 426c.Mod.Core-C4b and Optional Boost Regimen With HIV Trimer BG505 SOSIP.GT1.1 gp140, Both Adjuvanted With 3M-052-AF + Alum in Healthy, Adult Participants Without HIV

NCT03825536Phase 4CompletedPrimary

Effect of Methamphetamine on Residual Latent HIV Disease Study

NCT05459077Not ApplicableNot Yet Recruiting

Addressing Barriers to Anti-hypertensive Medication Adherence Among PLWH Who Have Achieved Viral Suppression

NCT07293559RecruitingPrimary

Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States

NCT06337032Phase 4RecruitingPrimary

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

NCT04150068Phase 2Active Not RecruitingPrimary

Study to Evaluate the Safety and Efficacy of Lenacapavir (GS-6207) in Combination With an Optimized Background Regimen (OBR) in Heavily Treatment Experienced Participants Living With HIV-1 Infection With Multidrug Resistance

NCT05869643Phase 2RecruitingPrimary

A Clinical Trial of STP0404 in Adults With HIV-1 Infection

NCT07001319Phase 1RecruitingPrimary

Study of GS-3242 in Participants With HIV-1; Substudy-05

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