Key Insights

Highlights

Success Rate

80% trial completion

Clinical Risk Assessment

Based on trial outcomes

High Risk

Score: 62/100

Termination Rate

3.0%

1 terminated out of 33 trials

Success Rate

80.0%

-6.5% vs benchmark

Late-Stage Pipeline

9%

3 trials in Phase 3/4

Results Transparency

0%

0 of 4 completed with results

Key Signals

80% success

Data Visualizations

Phase Distribution

25Total
Not Applicable (3)
P 1 (10)
P 2 (9)
P 3 (3)

Trial Status

Recruiting21
Completed4
Active Not Recruiting4
Not Yet Recruiting3
Terminated1

Trial Success Rate

80.0%

Benchmark: 86.5%

Based on 4 completed trials

Clinical Trials (33)

Showing 20 of 20 trials
NCT06319027Phase 2RecruitingPrimary

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

NCT07452458Phase 3Not Yet RecruitingPrimary

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

NCT04145115Phase 2Active Not Recruiting

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

NCT04528680Phase 1Active Not Recruiting

Ultrasound-based Blood-brain Barrier Opening and Albumin-bound Paclitaxel and Carboplatin for Recurrent Glioblastoma

NCT06419946Phase 3RecruitingPrimary

Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma

NCT07468136Phase 1Not Yet Recruiting

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

NCT07301268Phase 2RecruitingPrimary

GI-102 Alone or With Pembrolizumab Before Surgery for Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma

NCT04197934Phase 1Active Not Recruiting

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

NCT06047379Phase 1Recruiting

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

NCT05236036Phase 1Active Not Recruiting

Mycophenolate Mofetil in Combination With Standard of Care for the Treatment of Glioblastoma

NCT06095375Phase 1CompletedPrimary

Regorafenib With Temozolomide With or Without RT in MGMT-Methylated, IDH Wild-type GBM Patients

NCT05879250Phase 2RecruitingPrimary

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

NCT06359379Phase 2TerminatedPrimary

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

NCT04945148Phase 2RecruitingPrimary

Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy Temozolomide

NCT07091864Not ApplicableRecruitingPrimary

Continuous Glucose Monitoring for the Management of Hyperglycemia in Patients With Glioblastoma

NCT07223034Phase 1Recruiting

A Study of 177Lu-PSMA-617 in People With Gliomas

NCT05929495Phase 2RecruitingPrimary

Phase 2, Open-label, Single-arm Study on the Use of Metformin as Adjunctive Therapy in High-grade Glioma

NCT05375318Completed

BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels

NCT05879367Phase 1RecruitingPrimary

Evaluation of Eflornithine Plus Temozolomide in Patients With Newly Diagnosed Glioblastoma or Astrocytoma

NCT05941234Not ApplicableRecruitingPrimary

Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence in Glioblastoma

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