Key Insights

Highlights

Success Rate

85% trial completion

Published Results

14 trials with published results (8%)

Research Maturity

81 completed trials (44% of total)

Clinical Risk Assessment

Based on trial outcomes

Moderate Risk

Score: 52/100

Termination Rate

7.7%

14 terminated out of 183 trials

Success Rate

85.3%

-1.3% vs benchmark

Late-Stage Pipeline

13%

24 trials in Phase 3/4

Results Transparency

17%

14 of 81 completed with results

Key Signals

14 with results85% success14 terminated

Data Visualizations

Phase Distribution

112Total
Not Applicable (83)
P 1 (1)
P 2 (4)
P 3 (10)
P 4 (14)

Trial Status

Completed81
Unknown56
Recruiting19
Terminated14
Active Not Recruiting4
Not Yet Recruiting4

Trial Success Rate

85.3%

Benchmark: 86.6%

Based on 81 completed trials

Clinical Trials (183)

Showing 20 of 20 trials
NCT05703919Phase 4RecruitingPrimary

Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease

NCT04320342Phase 3Completed

A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD

NCT05687396Not ApplicableCompletedPrimary

Virtual Reality in COPD Exacerbation

NCT03464695Not ApplicableCompletedPrimary

Automated Oxygen Delivery by O2matic to Patients Admitted With an Exacerbation in COPD

NCT07791992Withdrawn

Combination of High-flow Nasal Oxygen (Optiflow) and Vibrating Membrane Nebuliser (Aerogen) in the Pre-hospital Setting - Before/After Study

NCT07721922Phase 4Not Yet RecruitingPrimary

Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Patients Presenting to the Emergency Department With Acute Exacerbation of COPD (ECOPD)

NCT05854901Not ApplicableCompletedPrimary

PCT-guided Treatment Regarding Antibiotic Use for Acute COPD Exacerbations

NCT06118632TerminatedPrimary

Physiological and Environmental Data in a Remote Setting to Predict Exacerbation Events in Patients With Chronic Obstructive Pulmonary Disease

NCT07554352RecruitingPrimary

Early Detection of COPD Exacerbations Using Home Monitoring Device

NCT04655170Phase 4CompletedPrimary

Feasibility, Safety and Efficacy of Nebulized Long-Acting Bronchodilators (Formoterol and Revefenacin) vs. Short-Acting Bronchodilators (Albuterol and Ipratropium) in Hospitalized Patients With AECOPD

NCT07351929Not ApplicableActive Not RecruitingPrimary

Emotional-distress-based Integrated Care Programme in Patients With an Acute Exacerbation of COPD

NCT04234360Phase 3TerminatedPrimary

Eosinophil-driven Corticotherapy for Patients Hospitalized for COPD Exacerbation

NCT04669743Not ApplicableActive Not Recruiting

Innate Immunity in Ozone-induced Airway Inflammation in COPD

NCT04860375Not ApplicableRecruiting

Multidisciplinary Management of Severe COPD

NCT04789057Phase 4Active Not Recruiting

Atorvastatin Effect on Reduction of COPD Exacerbations

NCT05825014RecruitingPrimary

Predicting Adverse Outcomes Using Machine Learning of COPD Patients in Hong Kong

NCT04223050Phase 4TerminatedPrimary

Comparing Mortality for Low vs High Peripheral Oxygen Saturation in COPD-patients With Acute Exacerbation

NCT05819164Not ApplicableCompletedPrimary

Comparison of Multiple Oxygenation Targets With Different Oximeters in Chronic Obstructive Pulmonary Disease (COPD) and Non-COPD Patients- Impact on Oxygen Flows

NCT07076290Phase 1Not Yet Recruiting

A Repeat Ascending Dosing Study of the Safety and Clinical Activity of R-3750 in Patients With Mild to Moderate COPD

NCT04481555Phase 4Completed

Eosinophil-guided Reduction of Inhaled Corticosteroids

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