Pulmonary Rehabilitation for COPD Patients: Can Performance Predict Exacerbation?

NCT05492149 | Completed

• 1 other identifier: 2022-A00210-43
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of pulmonary rehabilitation is to improve exercise capacity and reduce dyspnoea. As well as improving the patient's overall condition, pulmonary rehabilitation provides a means to monitor the patient regularly. During physical exercise, the increased activity of the muscle system increases cardiac and respiratory output. If the patient's respiratory status deteriorates, as occurs, for example, before the onset of an exacerbation, exercise capacity could be reasonably expected to reduce. The investigators hypothesised, therefore, that changes in the physical capacity of patients with COPD during a rehabilitation session could provide a predictive indication regarding the risk of occurrence of exacerbation.

Conditions

COPD; COPD Exacerbation; Pulmonary Rehabilitation

Outcome Measures

Primary Outcomes (1)

• Correlation between the decrease of performance during pulmonary rehabilitation session and the occurrence of pulmonary exacerbation.

  The change in performance rehabilitation of patients between the last session will be screen when a patients will be admitted to hospital for a COPD exacerbation.

  From admission to the program or first documented session ; to completion of the pulmonary rehabilitation program or occurrence of an exacerbation, up to 104 weeks.

Secondary Outcomes (1)

• Correlation between the decrease of performance during pulmonary rehabilitation session and the COPD Assessment Test (CAT) questionnaire score.

  Through study completion, at every pulmonary rehabilitation session ; to completion of the pulmonary rehabilitation program or occurrence of an exacerbation, up to 104 weeks.

Study Arms (1)

Pulmonary rehabilitation group

Patients referred for a pulmonary rehabilitation program will be follow up.

Other: Performance follow-up

Interventions

Performance follow-up OTHER

Diary performance during rehabilitation will be collected and a CAT questionnaire will be completed by the patient.

Pulmonary rehabilitation group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

COPD patients who referred to a pulmonary rehabilitation program

You may qualify if:

• Adult patients
• COPD patients

You may not qualify if:

• Patients who not performed not at least 5 sessions of the pulmonary rehabilitation program
• Occurence of an adverse event that prevents further rehabilitation
• Exacerbation in the previous month

Sponsors & Collaborators

• Groupe Hospitalier du Havre: lead

Study Sites (1)

Groupe Hospitalier du Havre

Montivilliers, Groupe Hospitalier Du Havre, 76290, France

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 26, 2022
• First Posted: August 8, 2022
• Study Start: September 1, 2022
• Primary Completion: September 1, 2024
• Study Completion: December 1, 2024
• Last Updated: January 21, 2026

Record last verified: 2026-01

Locations

FR (1)