Acute-On-Chronic Liver Failure
83
15
16
17
Key Insights
Highlights
Success Rate
85% trial completion
Clinical Risk Assessment
Based on trial outcomes
High Risk
Score: 62/100
3.6%
3 terminated out of 83 trials
85.0%
-1.5% vs benchmark
8%
7 trials in Phase 3/4
12%
2 of 17 completed with results
Key Signals
Data Visualizations
Phase Distribution
Trial Status
Trial Success Rate
Benchmark: 86.5%
Based on 17 completed trials
Clinical Trials (83)
Efficacy, Safety and Tolerability of VS-01 in Adult Patients With Acute-on-Chronic Liver Failure and Ascites (UNVEIL-IT)®
Chinese Phase II Trail of AS1501 in Acute-on-chronic Liver Failure (ACLF) Patients
Comparison of Blood Products Required Using Two Different ROTEM Cut-offs Before Invasive Procedures in Cirrhosis and Acute on Chronic Liver Failure (ACLF) Patients With Severe Coagulopathy
Efficacy and Safety of BMSCs (CG-BM1) for ACLF Patients
The Effects of Double Plasma Molecular Adsorption System in Acute on Chronic Liver Failure Patients
Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5%
COOLEY- Study: aCute On chrOnic Liver failurE Using the cYtosorb Device
Efficacy and Safety of Cytokine Adsorption and Plasma Exchange in Patients With ACLF and Sepsis
Pharmacokinetic Study on G1090N (Nitazoxanide) Capsules in Healthy Volunteers
Risk Factors Affecting MSC Efficacy in ACLF Patients
F573 for Injection for the Treatment of Liver Injury/Failure
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Phase I Study on Safety and Efficacy of Mesenchymal Stem-Cell (MSC) Therapy in Non-Viral Acute-on-Chronic Liver Failure (ACLF)
National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem Cell Therapy in Non-viral Acute on Chronic Liver Failure (ACLF) Patient- Phase-II Trial
National Collaborative Centre for Hepatic Regenerative Medicine (NC-CHRM): Evaluating Mesenchymal Stem-Cell (MSC) Therapy in Non-viral Acute on Chronic Liver Failure (ACLF) Patients - Phase-III Trial
A-TANGO Phase 2 Study
Micro-encapsulated Hepatocyte Intraperitoneal Transplantation in Liver Failure Adults
Anti-fungal Strategies in Acute-on-Chronic Liver Failure Patients
Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF)
Phase I Trial of QH-1A Hybrid Bio-Artificial Liver With Ex Vivo Blood-Purifying MSCs in Acute-on-Chronic Liver Failure