Comparison of the Efficacy of Negative Pressure Wound Therapy Versus Moist Wound Dressing in Diabetic Foot Ulcer Patients
Sponsor study identifier
interventional
60
1 country
1
Study Start
November 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Primary Completion
May 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
June 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Diabetic foot ulcer is a common and disabling complication of diabetes mellitus. This randomized controlled trial will be conducted at Abbas Institute of Medical Sciences, Muzaffarabad to compare the efficacy of negative pressure wound therapy versus conventional moist wound dressing. A total of 60 patients aged 18-70 years with diabetic foot ulcer size greater than 3 cm will be randomly divided into two groups of 30 patients each. Group A will receive negative pressure wound therapy and Group B will receive moist wound dressing. Efficacy will be measured in terms of healing time and reduction in ulcer size after 4 weeks of treatment.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
October 21, 2026
Actual (reported)October 27, 2026
Actual (reported)November 2026
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
May 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
June 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Efficacy of Negative Pressure Wound Therapy versus Moist Wound Dressing
Efficacy defined as wound healing within 4 weeks and greater than 3 cm reduction in ulcer size. Ulcer size measured as product of two largest perpendicular diameters in cm\^2 . Healing time measured in days from application of first dressing to appearance of granulation tissue.
4 weeks
Reduction in ulcer size
4 weeks
NPWT applied with vacuum assisted closure device, 100-125 mmHg, changed every 48-72 hours for 4 weeks
Moist wound dressing with normal saline soaked gauze, changed daily for 4 weeks
NPWT will be applied using Vacuum Assisted Closure device at 100-125 mmHg pressure, dressing changed every 48-72 hours for 4 weeks
Moist wound dressing with normal saline soaked gauze, dressing changed daily for 4 weeks
Abbas Institute of Medical Sciences Muzaffarabad
Muzaffarabad, Azad Kashmir, 13100, Pakistan
Ahsan Ahmed, FCPS
Abbas Institute of Medical Sciences Muzaffarabad.
First Submitted
October 21, 2026
First Posted
October 27, 2026
Study Start
November 2026
Diabetes Related Foot Ulcers With Negative Pressure Wound Therapy
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Planned date reported by the registry; this milestone is not confirmed as achieved.
Primary Completion
May 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Study Completion
June 2027
EstimatedPlanned date reported by the registry; this milestone is not confirmed as achieved.
Last Updated
October 28, 2026
Record last verified: 2026-10
No plan to share individual participant data
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Source: ClinicalTrials.gov.
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