Pulmonary and Musculoskeletal Impairments in Parkinson's Patients

NCT07843667 | Completed

• 1 other identifier: Impairments in Parkinson
• Study Type: observational
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, the relationships between pain severity, chest mobility, cough strength, muscle strength, physical activity levels, and quality of life in Parkinson's disease patients will be investigated.

Conditions

Parkinson Disease

Keywords

pain; chest mobility; muscle strength; physical activity; quality of life

Outcome Measures

Primary Outcomes (1)

• Total quality of life score evaluated by Parkinson's Disease Questionnaire (PDQ-39) questionnaire.

  The status of quality of life was evaluated using Parkinson's Disease Questionnaire (PDQ-39) questionnaire. Parkinson's Disease Questionnaire-39 (PDQ39) is a 39-item quality of life questionnaire. Evaluation for each question item ranges from 0 (no problem) to 4 (constant problem). Low scores in total indicate an improvement in people's quality of life.

  through study completion, an average of 1 year

Secondary Outcomes (5)

• Cough Strength

  through study completion, an average of 1 year

• Daily average step count

  through study completion, an average of 1 year

• Hand grip strength

  through study completion, an average of 1 year

• Chest mobility

  through study completion, an average of 1 year

• Cognitive status

  through study completion, an average of 1 year

Study Arms (1)

Parkinson's disease group

This group will consist of individuals with Parkinson disease.

Other: Physical Evaluations of Individuals with Parkinson's Disease

Interventions

Physical Evaluations of Individuals with Parkinson's Disease OTHER

In this study, data regarding chest mobility, cough strength, muscle strength, physical activity, and quality of life-collected from Parkinson's patients via face-to-face interviews-will be analyzed. The data for all these assessments were collected in a single session lasting a maximum of approximately one hour. Step counts for each individual were tracked using a pedometer over a period of three days.

Parkinson's disease group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

At least 30 Parkinson's patients will be included in the analyses.

You may qualify if:

• Being over 18 years old,
• Volunteering to participate in the research,
• Being diagnosed with Parkinson's disease
• Comorbid conditions (such as hypertension, diabetes) are under control
• Being able to perceive assessments (Standardized Mini Mental Test score of 24 and above)
• Having the ability to ambulate and walk independently
• Being in stage 1 - 4 according to the Modified Hoehn-Yahr Scale

You may not qualify if:

• Sudden drug or dose change during the study period
• A history of any acute/chronic orthopedic, cardiovascular, pulmonary, psychiatric or neuromuscular disease that may prevent measurements from being made.
• Having had myocardial infarction and pulmonary embolism in the last 30 days,
• Having a history of additional neurological (stroke, head trauma, peripheral nerve diseases, brain and spinal cord tumors, etc.) diseases other than Parkinson's disease
• Having severe vision loss or vestibular dysfunction
• Patients with blood pressure values above 140/90 and below 90/50 in blood pressure measurements made before the study, with arrhythmia on ECG, with a history of shortness of breath and/or palpitation

Sponsors & Collaborators

• Izmir Democracy University: lead

Study Sites (1)

Izmir Democracy University

Izmir, 35140, Turkey (Türkiye)

Location

Related Publications (1)

• Shalash A, Roushdy T, Essam M, Fathy M, Dawood NL, Abushady EM, Elrassas H, Helmi A, Hamid E. Mental Health, Physical Activity, and Quality of Life in Parkinson's Disease During COVID-19 Pandemic. Mov Disord. 2020 Jul;35(7):1097-1099. doi: 10.1002/mds.28134. Epub 2020 Jun 7. No abstract available.

  PMID: 32428342 BACKGROUND

MeSH Terms

Conditions

Parkinson Disease; Pain; Motor Activity

Condition Hierarchy (Ancestors)

Parkinsonian Disorders; Basal Ganglia Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Movement Disorders; Synucleinopathies; Neurodegenerative Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Behavior

Study Officials

• GÜLŞAH BARĞI, Assoc Prof

  Izmir Democracy University

  STUDY DIRECTOR

• MERVE ŞAHİN

  Izmir Democracy University

  PRINCIPAL INVESTIGATOR

• ÖZLEM ÇİNAR ÖZDEMİR

  Abant Izzet Baysal University

  PRINCIPAL INVESTIGATOR

• YASEMİN ÜNAL

  Bandirma Health Practice and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: September 21, 2026
• First Posted: September 28, 2026
• Study Start: May 13, 2023
• Primary Completion: August 30, 2024
• Study Completion: December 30, 2024
• Last Updated: September 28, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)