Clinical Presentation of Celiac Disease in Last 14 Years

NCT07842848 | Completed

• 1 other identifier: MD-203-2023
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to:

• To determine the pattern of clinical presentations of celiac disease (CD) over the past 10 - 14 years in Egyptian children.
• To study the various clinical presentation of CD in Egyptian children.
• To evaluate the pattern of CD in relation to different age groups in our children.
• To correlate between the clinical presentations of celiac disease and the upper GIT endoscopic findings.

Conditions

Clinical Presentation; Celiac Disease

Outcome Measures

Primary Outcomes (1)

• Pattern of Clinical Presentations of Pediatric Celiac Disease

  The percentage of children presenting with celiac disease will be determined.

  12 months post-procedure

Study Arms (1)

Study group

Children aged 6 months to 15 years diagnosed with celiac disease and followed at the Pediatric Gastroenterology Clinic of Cairo University Children's Hospital between January 2009 and December 2023. Clinical, laboratory, serological, endoscopic, and histopathological data will be retrospectively extracted from their medical records. Patients will be analyzed according to the period of diagnosis (2009-2011, 2012-2019, or 2020-2023) and age at diagnosis (\<2 years, 2-5 years, or \>5-15 years).

Other: Retrospective Medical Record Review

Interventions

Retrospective Medical Record Review OTHER

No therapeutic or diagnostic intervention will be administered as part of this study. Existing medical records will be retrospectively reviewed to collect demographic, clinical, laboratory, serological, endoscopic, and histopathological data relating to children diagnosed with celiac disease between January 2009 and December 2023.

Study group

Eligibility Criteria

• Age: 6 Months - 15 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children diagnosed with Celiac disease by clinical picture and laboratory investigations, following in pediatric gastroenterology clinic of Cairo University children's hospital in past 14 years

You may qualify if:

• Children in the age range from 6 months to 15 years diagnosed with Celiac disease.
• Any sex.

You may not qualify if:

• Age less than 6 months or more than 15 years.
• Patients or parents unwilling to share their personal, social and medical data or refuse to participate in the study.
• Celiac disease patients with other gastrointestinal or non-gastrointestinal diseases (e.g., inflammatory bowel disease) that might interfere with data interpretation.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Cairo University

Cairo, 12613, Egypt

Location

MeSH Terms

Conditions

Celiac Disease

Condition Hierarchy (Ancestors)

Malabsorption Syndromes; Intestinal Diseases; Gastrointestinal Diseases; Digestive System Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: PhD student

Study Record Dates

• First Submitted: September 21, 2026
• First Posted: September 25, 2026
• Study Start: March 1, 2024
• Primary Completion: December 1, 2025
• Study Completion: December 1, 2025
• Last Updated: September 25, 2026

Record last verified: 2026-09

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL
• Time Frame: After the end of study for one year.
• Access Criteria: The data will be available upon a reasonable request from the corresponding author.

Locations

EG (1)