NCT06164548

Brief Summary

Detect the prevalence of celiac disease in children with unexplained short stature attended at Assiut University Children Hospital.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2024

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 2, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 11, 2023

Completed
1 month until next milestone

Study Start

First participant enrolled

January 15, 2024

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2024

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 31, 2025

Completed
Last Updated

December 11, 2023

Status Verified

December 1, 2023

Enrollment Period

12 months

First QC Date

December 2, 2023

Last Update Submit

December 2, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Celiac Disease Among Egyptian Children With Unexplained Short Stature

    Detect prevalence of celiac disease in children presented with unexplained short stature

    Baseline

Eligibility Criteria

Age2 Years - 18 Years
Sexall
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Children aged between 2-18 years with undetectable causes of short stature

You may qualify if:

  • (1) Children aged between 2-18 years with undetectable causes of short stature whose height was \< -2 SDfor the ageandsexaccording to Z score growth references for Egyptianchildrenand adolescent growth reference and Control DiseaseCenter(CDC) charts. (2) Short children not previously screened for Celiac disease.

You may not qualify if:

  • Short children with demonstrable cause such as:
  • (1) Familial and constitutional short stature. (2) Chronic illness. (3) Disproportionate short stature. (4) Short stature of endocrinal origin (eg, growth hormone deficiency). (5) Turner syndrome. (6) Short stature with significant congenital anomalies. (7) Patients on gluten free diet.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (5)

  • Voss LD, Mulligan J, Betts PR, Wilkin TJ. Poor growth in school entrants as an index of organic disease: the Wessex growth study. BMJ. 1992 Dec 5;305(6866):1400-2. doi: 10.1136/bmj.305.6866.1400.

    PMID: 1486305BACKGROUND
  • Ertekin V, Selimoglu MA, Kardas F, Aktas E. Prevalence of celiac disease in Turkish children. J Clin Gastroenterol. 2005 Sep;39(8):689-91. doi: 10.1097/01.mcg.0000174026.26838.56.

    PMID: 16082278BACKGROUND
  • Ahmed ML, Allen AD, Sharma A, Macfarlane JA, Dunger DB. Evaluation of a district growth screening programme: the Oxford Growth Study. Arch Dis Child. 1993 Sep;69(3):361-5. doi: 10.1136/adc.69.3.361.

    PMID: 7692826BACKGROUND
  • Itzlinger A, Branchi F, Elli L, Schumann M. Gluten-Free Diet in Celiac Disease-Forever and for All? Nutrients. 2018 Nov 18;10(11):1796. doi: 10.3390/nu10111796.

    PMID: 30453686BACKGROUND
  • Jericho H, Sansotta N, Guandalini S. Extraintestinal Manifestations of Celiac Disease: Effectiveness of the Gluten-Free Diet. J Pediatr Gastroenterol Nutr. 2017 Jul;65(1):75-79. doi: 10.1097/MPG.0000000000001420.

    PMID: 28644353BACKGROUND

MeSH Terms

Conditions

Celiac Disease

Condition Hierarchy (Ancestors)

Malabsorption SyndromesIntestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Central Study Contacts

Esraa Atef Shehataa

CONTACT

Shereen Mansour Galal, As.Professor

CONTACT

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
71515,Assiut

Study Record Dates

First Submitted

December 2, 2023

First Posted

December 11, 2023

Study Start

January 15, 2024

Primary Completion

December 31, 2024

Study Completion

March 31, 2025

Last Updated

December 11, 2023

Record last verified: 2023-12