Comparative Effects of Post Isometric Relaxation and Reciprocal Inhibition in Individuals With Cervicogenic Headache.
1 other identifier
interventional
46
1 country
1
Brief Summary
This study aims to compare the effects of Post Isometric Relaxation (PIR) and Reciprocal Inhibition (RI) in individuals with cervicogenic headache, a secondary headache originating from dysfunction of the cervical spine, particularly the upper cervical segments. Cervicogenic headache is characterized by unilateral head and neck pain, restricted cervical mobility, muscle tightness, and functional limitations that negatively affect daily activities and quality of life. The study will employ a randomized controlled trial involving 46 participants aged 18-45 years who meet the inclusion criteria. Participants will be randomly allocated into two groups: Group A will receive Post Isometric Relaxation, while Group B will receive Reciprocal Inhibition. Both groups will also receive a standard physiotherapy protocol consisting of hot packs, cervical isometric exercises, and C1-C2 Sustained Natural Apophyseal Glides (SNAGs), administered three times per week for four weeks. Pain intensity, functional disability, and cervical range of motion will be assessed before and after the intervention using the Numeric Pain Rating Scale (NPRS), Neck Disability Index (NDI), and goniometric measurements, respectively. By comparing these two muscle energy techniques, the study seeks to determine which intervention is more effective in reducing pain, improving cervical mobility, and enhancing functional outcomes, thereby providing evidence to support clinical decision-making and optimize physiotherapy management for individuals with cervicogenic headache.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Feb 2026
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 12, 2026
CompletedFirst Submitted
Initial submission to the registry
September 18, 2026
CompletedFirst Posted
Study publicly available on registry
September 24, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 18, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 18, 2027
September 24, 2026
September 1, 2026
10 months
September 18, 2026
September 18, 2026
Conditions
Outcome Measures
Primary Outcomes (3)
Head Pain
Pain intensity will be assessed using the Numeric Pain Rating Scale(NPRS).The NPRS is an 11-point self reported scale ranging from 0 to 10,where 0 indicates no pain and 10 reprents the worst pain.
Baseline and after 4 weeks of intervention
Cervical Range of Motion
Cervical range of motion (ROM) will be assessed as an outcome measure using a goniometer. The assessment will be performed before the intervention and after completion of the treatment protocol to determine changes in cervical mobility. The cervical movements assessed will include flexion, extension, right and left lateral flexion, and right and left rotation. The participant will be positioned appropriately, and the goniometer will be aligned according to the anatomical landmarks for each movement. The available cervical ROM will be measured in degrees and recorded on the data collection form. Goniometry has demonstrated good reliability for assessing cervical ROM, with reported intraclass correlation coefficients (ICC) ranging from 0.79 to 0.98.
Baseline and after 4 weeks of treatment
Neck Disability
Neck disability will be assessed as an outcome measure using the Neck Disability Index (NDI). The NDI is a valid and reliable self-report questionnaire designed to evaluate the level of disability associated with neck pain and its effects on daily activities. It consists of 10 items covering pain intensity, personal care, lifting, reading, headaches, concentration, work, driving, sleeping, and recreation. Each item is scored from 0 to 5, with higher scores indicating greater disability. The total score ranges from 0 to 50 and is used to determine the severity of functional disability. A score of 0-4 indicates no disability, 5-14 mild disability, 15-24 moderate disability, 25-34 severe disability, and 35 or more complete disability.
Baseline and after 4 weeks of treatment
Study Arms (2)
Group A Post Isometric Relaxation
EXPERIMENTALGroup B Reciprocal Inhibition
EXPERIMENTALInterventions
Post Isometric Relaxation (PIR) is a muscle energy technique used to reduce pain, decrease muscle tightness, and improve cervical mobility in individuals with cervicogenic headache. The technique is based on the principle that muscle tone temporarily decreases after a gentle isometric contraction, allowing the muscle to be stretched more effectively. During the intervention, the therapist positions the affected muscle at its resistance barrier and asks the patient to perform a 10-second isometric contraction against therapist-applied resistance. After relaxation, a gentle passive stretch is applied to achieve a new range of motion. The procedure is repeated 3-5 times for each targeted muscle, including the upper trapezius, levator scapulae, suboccipital, and sternocleidomastoid muscles.
Reciprocal Inhibition (RI) is a muscle energy technique used to reduce muscle tightness, relieve pain, and improve cervical range of motion by utilizing the neurological principle of reciprocal inhibition. During the technique, the therapist positions the patient appropriately and instructs the patient to perform a gentle 10-second isometric contraction of the antagonist muscle against therapist-applied resistance. This contraction inhibits the activity of the tight agonist muscle, resulting in decreased muscle tone and facilitating relaxation. Following the contraction, the therapist applies a gentle passive stretch to the affected muscle to achieve a new range of motion. The technique is repeated 3-5 times for each targeted muscle to improve flexibility and cervical function.
Eligibility Criteria
You may qualify if:
- Patients are diagnosed according to ICH criteria.
- Age 18-45 years.
- Both Genders (Male and Female).
- Headache \> 3 months.
- Unilateral neck pain and associated headache.
- Headache is precipitated by neck movements or sustained positions.
- Restricted upper cervical segmental mobility.
- Positive cervical flexion rotation test, restriction greater than 10°.
You may not qualify if:
- History of head and neck trauma.
- Neoplasm.
- Cognitive disability.
- Inherited disorders such as scoliosis and torticollis.
- Other chronic pain syndrome (i.e.: fibromyalgia, systematic inflammatory disease).
- History of recent surgery of cervical spine.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Foundation University College of Physical Therapy
Islamabad, Punjab Province, 44000, Pakistan
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 18, 2026
First Posted
September 24, 2026
Study Start
February 12, 2026
Primary Completion (Estimated)
December 18, 2026
Study Completion (Estimated)
January 18, 2027
Last Updated
September 24, 2026
Record last verified: 2026-09