Study on the Prevention of Weight Loss Through Physical Activity Among Nursing Home Residents
EAT-PA
2 other identifiers
interventional
596
1 country
1
Brief Summary
Appetite loss is frequent in institutionalized older adults. Physical activity is known for its benefits on appetite regulation but its effects in nursing home residents remain poorly investigated. This project will investigate the 6-month longitudinal relationships between daily physical activity time with appetite and bodyweight and how engaging in a 6-month regular exercise program can improve theses outcomes in older institutionalized older adults.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Sep 2026
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2026
CompletedFirst Submitted
Initial submission to the registry
September 10, 2026
CompletedFirst Posted
Study publicly available on registry
September 21, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 1, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
September 1, 2028
September 21, 2026
September 1, 2026
2 years
September 10, 2026
September 17, 2026
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Changes in bodyweight
It will be assessed by measuring the bodyweight (kg) seven times (initially and once a month). For the observational arm, it will be measured based on daily physical activity (min/day) as measured by activity trackers. For the interventional arm, it will be measured based on participation in the physical activity program (ratio of sessions attended to sessions scheduled) over a 6-months period.
6 months
Secondary Outcomes (15)
Changes in the score of the SNAQ questionnaire
6 months
Changes in the nutrition evaluation
6 months
Patients' healthcare consumption
6 months
Efficiency of the physical exercise program assessed using costs from the community's perspective and QALYs
6 months
Baseline blood concentrations of leptin, insulin, and GDF-15 at the inclusion
On inclusion
- +10 more secondary outcomes
Study Arms (2)
Interventional
EXPERIMENTALParticipants in the intervention group will take part in group physical exercise sessions for 6 months (groups of 5 persons).
Observational
OTHERParticipants will not receive any specific care. They will simply need to wear activity trackers on two separate occasions over the course of a week: from M0 to M0 + 1 week and from M6 to M6 + 1 week.
Interventions
The participants will partake in physical activity sessions twice a week for about 45-60 minutes each which will consist of exercises designed to improve mobility, motor skills, balance, strength and muscular endurance, as well as the cardiorespiratory system. All exercises will be tailored to each person's abilities and can be performed while sitting or standing.
The appetite will be evaluated by a self-assessment questionnaire SNAQ.
It will be assessed by the healthcare team of the patient at baseline and at the end of the study.
It will be evaluated by a self-assessment questionnaire EQ-5D-5L.
A blood test will be done at the beginning of the study to evaluate the blood concentrations of leptin, insulin and GDF-15.
It will be done at the end of the study (month 6) to evaluate the changes in blood concentrations of leptin, insulin and GDF-15.
The functional capacities will be assessed by : * Mini-Mental State Examination (MMSE) for cognition * Mini Nutritional Assessment (MNA) short form for nutrition * Whisper test for hearing * step-1 ICOPE question for vision * Short Physical Performance Battery (SPPB) and grip strength for mobility * Montgomery-Ã…sberg Depression Rating Scale (MADRS) and PHQ-2 for mood
the weight will be measured every month (kilogramm).
Eligibility Criteria
You may qualify if:
- For both the observational and interventional parts:
- Be a resident in a nursing home (EHPAD).
- Be affiliated with the social security system.
- Be aged 65 years or older.
- Have a GIR score \> 2.
- Be able to walk 4 meters (with a walking aid if necessary, but without human assistance).
- Provide written consent
- For the interventional part only:
- \- Be able to understand instructions for performing the exercises.
You may not qualify if:
- For both the observational and interventional parts:
- Unstable cardiovascular disease or any other health condition contraindicating physical exercise.
- End-of-life situation identified in the medical record.
- Planned relocation to another facility during the 6-month follow-up period.
- To be under legal protection or guardianship
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University Hospital
Toulouse, 31 059, France
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Caroline Berbon, PHD
University Hospital, Toulouse
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 10, 2026
First Posted
September 21, 2026
Study Start
September 1, 2026
Primary Completion (Estimated)
September 1, 2028
Study Completion (Estimated)
September 1, 2028
Last Updated
September 21, 2026
Record last verified: 2026-09
Data Sharing
- IPD Sharing
- Will not share